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Clinical Applications of Immunomics, Andras Falus


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Цена: 27950.00р.
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Автор: Andras Falus
Название:  Clinical Applications of Immunomics
ISBN: 9781493900541
Издательство: Springer
Классификация:



ISBN-10: 1493900544
Обложка/Формат: Paperback
Страницы: 300
Вес: 0.46 кг.
Дата издания: 2008
Серия: Immunomics Reviews:
Язык: English
Издание: 2009 ed.
Иллюстрации: Xvi, 275 p.
Размер: 234 x 156 x 16
Читательская аудитория: General (us: trade)
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Innate immunity is one the most evolutionally conserved systems, designed to protect the organism from viruses and bacterial infections, stress and many other types of attacks from the outside world. During the past decade, the capacity of molecular biology and information technology to produce and analyse data have grown exponentially, rapidly reforming many aspects of immunology research in the post-genomics era. As a result, scientific understanding of signalling networks governing the innate immunity response in human tissues and other organisms has evolved beyond recognition, compared to even just a decade ago. Many strategies have been designed over the years to identify novel proteins, which have a crucial role in innate immunity responses by regulating particular signalling pathways. These projects had many advantages, including the definition of novel drug targets, as exemplified by the recent success of anti-TNF therapy, as well as leading to a better, system-wide understanding of the molecular control of innate immunity. In the past few years, a new concept, Immunomics, has been adopted to define an emerging, multidisciplinary field of research (Schonbach, 2003). Although rapid progress has been made to identify the proteins playing pivotal roles in the innate immunity–related signalling pathways (for example, TIR signalling pathways), the catalogue of proteins with a key regulatory function identified and studied is far from completed. Novel proteins need to be char- terised to gain a more comprehensive picture of how signalling networks are regulated.
Дополнительное описание: Integrative Systems Approaches to Study Innate Immunity.- Immunomics: At the Forefront of Innate Immunity Research.- Epitope-Based Immunome-Derived Vaccines: A Strategy for Improved Design and Safety.- Immunodeficiencies and Immunome: Diseases and Informa



Clinical Applications for Next Generation Sequencing

Автор: Urszula Demkow
Название: Clinical Applications for Next Generation Sequencing
ISBN: 0128017392 ISBN-13(EAN): 9780128017395
Издательство: Elsevier Science
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Цена: 12462.00 р.
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Описание:

Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments.

Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients.

The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia.

Acute Phase Proteins Molecular Biology, Biochemistry, and Clinical Applications

Автор: Mackiewicz
Название: Acute Phase Proteins Molecular Biology, Biochemistry, and Clinical Applications
ISBN: 0849369134 ISBN-13(EAN): 9780849369131
Издательство: Taylor&Francis
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Цена: 88044.00 р.
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Описание: This book covers major aspects of acute phase proteins (APP) starting with molecular mechanisms regulating their synthesis and ending with their functional significance. It is helpful for immunologists, biochemists, molecular biologists, cellular biologists, and clinical chemists.

Metabolomics: From Fundamentals to Clinical Applications

Автор: Alessandra Sussulini
Название: Metabolomics: From Fundamentals to Clinical Applications
ISBN: 3319476556 ISBN-13(EAN): 9783319476551
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine.

Hepatitis C Virus Disease / Immunobiology and Clinical Applications

Автор: Jirillo Emilio
Название: Hepatitis C Virus Disease / Immunobiology and Clinical Applications
ISBN: 0387713751 ISBN-13(EAN): 9780387713755
Издательство: Springer
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Цена: 25155.00 р.
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Описание: Innate immunity in Type C Hepatitis.- Mechanisms of Interferon Action and Resistance: Lessons learned from cell cultures studies.- Immunological Parameters Determining the Outcome of Hepatitis C Virus Infection.- The Effects of Interferon-Alpha Therapy on Immune Response and Outcome.- Microbial Components Associated with HCV Disease Interfere with Response to Interferon-alpha/Ribavarin Treatment.- IFN-induced Effector Proteins and HCV Replication.- Treatment of Chronic Hepatitis C with Various Genotypes.- IFNs in HCV infection: Biological and Clinical Considerations.- Clinical application of IFN-based therapy for HCV.- HCV therapy in difficult-to-treat patients.- Effects of IFN-alpha/Ribavirin Treatment on HCV Disease and Related Progression.    

The IGF System / Molecular Biology, Physiology, and Clinical Applications

Автор: Rosenfeld Ron G., Roberts Charles T.
Название: The IGF System / Molecular Biology, Physiology, and Clinical Applications
ISBN: 0896036928 ISBN-13(EAN): 9780896036925
Издательство: Springer
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Цена: 43100.00 р.
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Описание: Influential researchers comprehensively survey the basic and clinical aspects of the insulin-like growth factor system. Their state-of-the-art synthesis of a broad range of IGF research illuminates the interplay among ligands, receptors, and binding proteins, each exerting both the local and systemic effects that constitute this complex system. The book examines in detail not only the molecular biology, the biological actions, and the physiology of the various IGF systems, but also the clinical aspects of the IGF system, ultimately producing a useful paradigm for the investigation of related hormone, growth factor, and cytokine signaling systems. The IGF System: Molecular Biology, Physiology, and Clinical Applications is the first extended treatment of the IGF system in many years and is designed to serve as the new standard reference-of-choice for all basic and clinical investigators, as well as practicing physicians treating a range of human diseases, including cancer, diabetes, and neurodegenerative disorders.

Bioinformatics for Immunomics

Автор: Darren D.R. Flower; Matthew Davies; Shoba Ranganat
Название: Bioinformatics for Immunomics
ISBN: 1461424852 ISBN-13(EAN): 9781461424857
Издательство: Springer
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Цена: 30039.00 р.
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Описание: This fourth volume of a series is dedicated to advances in immunomics. The focus is on systemic and integrative approaches in basic and clinical immunology, immunoinformatics, and immunologically relevant instrumentation and high-throughput screening methods.


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