Gene Therapy for Autoimmune and Inflammatory Diseases, Yuti Chernajovsky; Paul D. Robbins
Автор: Ian R. Mackay Название: The Autoimmune Diseases, ISBN: 0123849292 ISBN-13(EAN): 9780123849298 Издательство: Elsevier Science Рейтинг: Цена: 25791.00 р. Наличие на складе: Поставка под заказ.
Описание: Since publication of the 4th Edition of The Autoimmune Diseases in 2006, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels and includes expanded coverage of autoinflammatory disease and autoimmune responses to tumors.
Автор: Heinz-Peter Schulthei?; Michel Noutsias (Eds.) Название: Inflammatory cardiomyopathy (dcmi) - pathogenesis and therapy ISBN: 3764383518 ISBN-13(EAN): 9783764383510 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Поставка под заказ.
Описание: Cardiomyopathy (CM) is one of the most frequent causes of heart failure. There are many different causes of the disease, therefore many different kinds of cardiomyopathies exist. This work focuses on inflammatory CM, belonging to the Dilated Cardiomyopathies (DCMi). It covers epidemiology, pathology, immunology, diagnosis and treatment strategies.
Автор: Vollenhoven Ronald Van Название: Clinical Therapy Research in the Inflammatory Diseases ISBN: 9814656321 ISBN-13(EAN): 9789814656320 Издательство: World Scientific Publishing Рейтинг: Цена: 11246.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This unique textbook provides information on the dramatic advances taking place in the field of inflammatory (autoimmune) diseases and their therapies.
Описание: Inflammatory disorders of the nervous system, although individually uncommon, collectively make up 10-20% of acute paediatric neurology presentations and many are potentially treatable Provides a detailed and comprehensive summary of the childhood diseases that are caused by the immune system and their treatments .
Автор: Nussinovitch, Udi Название: The Heart in Rheumatic, Autoimmune and Inflammatory Diseases ISBN: 0128032677 ISBN-13(EAN): 9780128032671 Издательство: Elsevier Science Рейтинг: Цена: 21054.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives.
This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe.
A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases.
Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches.
Presents an up-to-date "level of evidence" and "strengths of recommendations" for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.
Описание: This practical collection examines methodologies originating from the benefits of genome-wide approaches to studying epigenetics, which has opened the emerging field of epigenomics. Focusing on the areas of cancer, inflammatory and autoimmune disorders, chapters discuss three main components of the epigenome and their role in the regulation of gene expression and present a detailed method section specific to studying each component, including data analyses, troubleshooting, and feasibility in different experimental settings. The main topics are high-throughput and targeted methods for DNA methylation analysis, nucleosome position mapping, studying epigenetic effects of gut microbiota, optical imaging for detection of epigenetic aberrations in living cells, methods for microRNA, and histone code profiling. Written for the Methods in Pharmacology and Toxicology series, the book includes the kind of detail and implementation advice to encourage success in the lab.
Authoritative and easily applicable, Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases aims to provide pharmacologists, molecular biologists, bioinformaticians, and toxicologists with a vital background on epigenetics and state-of-the-art techniques in epigenomics.
Автор: Parnham Название: Compendium of Inflammatory Diseases ISBN: 3764385308 ISBN-13(EAN): 9783764385309 Издательство: Springer Рейтинг: Цена: 139754.00 р. Наличие на складе: Поставка под заказ.
Описание: Inflammation has become one of the most exciting and rewarding areas of medical research. Recent years have seen a revolution in our understanding of how blood and tissue cells interact and of the intracellular mechanisms controlling their activation. This has revealed the underlying inflammatory pathology of many diseases and provided multiple new targets for anti-inflammatory and immunomodulatory therapy. The Encyclopedia of Inflammatory Diseases will cover the following areas: * Inflammatory Processes and Cells * Inflammatory Diseases * Mediators of Inflammation * Pharmacology of Inflammation Since inflammatory diseases and their therapy cover a broad range of scientific and medical fields, the encyclopedia will be co-edited by four international experts, a clinician and three researchers from the disciplines of immunology, biochemistry, and pharmacology, in this way providing students, basic and clinical scientists and practitioners in academia, hospitals and industry with valuable interlinked information. This living project will serve as a reliable and comprehensive data pool for everybody working in inflammation research. Owing to its dynamic nature, it will grow with time and future editions, becoming an indispensible source of information for academia, clinical practitioners and industry.
Автор: Gupta Название: Anti-inflammatory Nutraceuticals and Chronic Diseases ISBN: 3319413325 ISBN-13(EAN): 9783319413327 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume focuses on anti-inflammatory nutraceuticals and their role in various chronic diseases. Food and Drug Administration (FDA) approved drugs such as steroids, non-steroidal anti-inflammatory drugs (NSAIDS), statins and metformin have been shown to modulate inflammatory pathways, but their long-term intake has been associated with numerous side effects. This means that there is enormous potential for dietary agents that can modulate inflammatory pathways in humans. Leading experts describe the latest research on the role of anti-inflammatory nutraceuticals in preventing and treating chronic diseases.
Автор: Heinz-Peter Schultheiss; Joachim-Friedrich Kapp; G Название: Chronic Viral and Inflammatory Cardiomyopathy ISBN: 3642421431 ISBN-13(EAN): 9783642421433 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Overview on Chronic Viral Cardiomyopathy/Chronic Myocarditis.-Unsolved Medical Issues and New Targets for Further Research in Viral Myocarditis and Dilated Cardiomyopathy.- Frontiers in Viral Diagnostics.- Is Virus Persistence a Determinant for Disease Progression?- Parvovirus B19 - The Causative Agent of Dilated Cardiomyopathy or an Harmless Passenger of the Human Myocard?- Parvovirus B19: A New Emerging Pathogenic Agent of Inflammatory Cardiomyopathy.- Role of Hepatitis C Virus in Cardiomyopathies.-Recent Insights into the Role of Host Innate and Acquired Immunity Responses.- The Significance of Autoimmunity in Myocarditis.- The Roles of Immunity and Autoimmunity in Chronic Heart Failure.- Clinical Implications of Anti-Cardiac Immunity in Dilated Cardiomyopathy.- Inflammation and Cardiac Remodeling During Viral Myocarditis.- Is There a Virus Specific Matrix Destruction in the Course of Disease in Dilated Cardiomyopathy?- New Non-Invasive Approaches for the Diagnosis of Cardiomyopathy: MRI.-New Therapeutics Targets in Chronic Viral Cardiomyopathy.-Anti-Viral Treatment in Patients with Virus-Induced Cardiomyopathy.- Immunosuppressive Treatment of Chronic Non-Viral Myocarditis.-Immunoabsorption in Dilated Cardiomyopathy
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