Biomechanics and Mechanobiology of Aneurysms, Tim McGloughlin

Автор: Chien
Название: Molecular and Cellular Mechanobiology
ISBN: 1493956159 ISBN-13(EAN): 9781493956159
Издательство: Springer
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Цена: 21661.00 р.
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Описание: This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.

Автор: Parachuri, V. Rao, Adhyapak, Srilakshmi M.
Название: Ventricular Geometry in Post-Myocardial Infarction Aneurysms
ISBN: 1447128605 ISBN-13(EAN): 9781447128601
Издательство: Springer
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Цена: 22359.00 р.
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Описание: The topic of heart failure although extensively researched and reported, has several gray areas. This is especially seen in determining strategies for combating advanced heart failure. The global burden of ischemic heart disease is increasing at an alarming rate to almost pandemic proportions. Even in the presence of state-of the art technology for prompt and successful coronary reperfusion, the population progressing to ischemic cardiomyopathy is substantial. The treatment strategies for ischemic cardiomyopathy do not always ensure optimal clinical results, the reasons for which are varied. The proper patient selection is vital as is the tailoring of suitable therapy. The approach is thus multi-pronged, of which surgical ventricular restoration (SVR) has a definite role. Despite various randomized studies like the STICH-hypothesis 2, where there was a huge selection bias, with patients subjected to an erroneous technique of SVR, with inadequate ventricular remodelling assessment. The present need is to understand the unique anatomy of the left ventricle, its function and perturbations with the onset of heart failure, in order to plan therapeutic strategies to restore near normal anatomy and function. A study of the hemodynamics in ischemic cardiomyopathy is essential, as it differs in certain aspects from other causes of heart failure like idiopathic dilated cardiomyopathy and valvular heart diseases. Since information on these aspects are scattered in various scholarly articles, a concise source in the form of a book would be appropriate and useful for both cardiologists and cardiac surgeons. This project represents a concise review of normal and abnormal cardiac anatomy and physiology, the evolution of SVR to EVLPP with validation of near normal ventricular restoration, plus act as a reference guide for cardiac surgeons with interest in SVR.

Автор: Karol Miller
Название: Biomechanics of the Brain
ISBN: 1461428289 ISBN-13(EAN): 9781461428282
Издательство: Springer
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Цена: 15672.00 р.
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Описание: With contributions from scientists at major institutions, this book presents an introduction to brain anatomy for engineers and scientists. It provides, for the first time, a comprehensive resource in the field of brain biomechanics.

Автор: Tzung K Hsiai
Название: Hemodynamics And Mechanobiology Of Endothelium
ISBN: 9814280410 ISBN-13(EAN): 9789814280419
Издательство: World Scientific Publishing
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Цена: 19008.00 р.
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Описание: The investigation of vascular biology and cardiovascular medicine is made possible by the use of tissue engineering, nanotechnology and stem cell research. This book represents a paradigm shift from the traditional static model of investigation of oxidative biology to the dynamic model of vascular oxidative stress.