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RNA Metabolism in Trypanosomes, Albrecht Bindereif


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Цена: 21661.00р.
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Автор: Albrecht Bindereif
Название:  RNA Metabolism in Trypanosomes
ISBN: 9783642433252
Издательство: Springer
Классификация:






ISBN-10: 3642433251
Обложка/Формат: Paperback
Страницы: 274
Вес: 0.43 кг.
Дата издания: 2012
Серия: Nucleic Acids and Molecular Biology
Язык: English
Издание: 2012 ed.
Иллюстрации: Vi, 274 p.
Размер: 234 x 156 x 15
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Trypanosomes are unicellular protozoa of ancient evolutionary origin that are responsible for several tropical diseases, such as African sleeping sickness. Over the last few decades, research in trypanosome biology has revealed many unique and fascinating features, many of which have helped to establish new paradigms in other biological systems. This applies in particular to studies in gene expression and regulation, which benefit enormously from the trypanosome genome projects and from the new genome-wide approaches recently introduced in trypanosome research. This volume covers the most important aspects of biosynthesis, processing, and functions of RNA in trypanosomes, ranging from transcription to RNA editing, mRNA splicing/translation/turnover, processing of transfer and ribosomal RNA, RNA interference, and current transcriptome-wide analyses. Recent progress in RNA-focused research in trypanosomatids promises to yield novel insights into trypanosome-specific features, as well as to reveal in the process new potential therapeutic strategies for combating these parasitic diseases.
Дополнительное описание: RNA Polymerases and Transcription Factors of Trypanosomes.- SL RNA biogenesis in kinetoplastids: a long and winding road.- Pre-mRNA splicing in Trypanosoma brucei: factors, mechanisms, and regulation.- mRNA turnover in trypanosomes.- tRNA biogenesis and p



Molecular Biology of RNA

Автор: Elliott Michael
Название: Molecular Biology of RNA
ISBN: 0199288372 ISBN-13(EAN): 9780199288373
Издательство: Oxford Academ
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Цена: 6493.00 р.
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Описание: Molecular Biology of RNA provides a broad survey of RNA structure and function. Describing the life cycle of an RNA, it reveals how hugely diverse gene products stem from a relatively modest gene pool. It also describes how RNA molecules have a range of biological functions beyond messenger RNA, including catalysts and regulatory molecules.

RNA Interference from Biology to Therapeutics

Автор: Howard
Название: RNA Interference from Biology to Therapeutics
ISBN: 1461447437 ISBN-13(EAN): 9781461447436
Издательство: Springer
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Цена: 28734.00 р.
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Описание: This volume addresses the role of different RNAi molecules in cellular processes as rational for diagnostic and therapeutic approaches. It covers RNAi therapeutic design to optimize siRNA potency and reduce off-target effects.

RNA Exosome

Автор: Jensen
Название: RNA Exosome
ISBN: 1441978402 ISBN-13(EAN): 9781441978400
Издательство: Springer
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Цена: 22359.00 р.
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Описание: Assembling work by prominent researchers in the field of RNA exosomes, this excellent introduction to the fascinating protein complex provides a comprehensive account of the proteins` many functions as well as a historical account of the field`s development.

Rna interference

Название: Rna interference
ISBN: 3540751564 ISBN-13(EAN): 9783540751564
Издательство: Springer
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Цена: 28734.00 р.
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Описание: In the last few years the major effect that RNAi has had in invertebrate systems is beginning to take hold in mammalian systems through both single gene knockdown experiments and genome-scale screens. Through the introduction of RNAi, mammalian systems have finally gained admittance to the pantheon of model genetic systems.

RNA Interference Technology

Автор: Appasani
Название: RNA Interference Technology
ISBN: 0521205174 ISBN-13(EAN): 9780521205177
Издательство: Cambridge Academ
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Цена: 8870.00 р.
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Описание: RNA Interference (RNAi) technology has rapidly become one of the key methods used in functional genomics. In this overview, the basic concepts of RNAi biology are discussed, as well as the current and potential applications, providing an invaluable reference for all those who need to understand this emerging technology.

Promoter Associated RNA

Автор: Sara Napoli
Название: Promoter Associated RNA
ISBN: 1493967142 ISBN-13(EAN): 9781493967148
Издательство: Springer
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Цена: 20962.00 р.
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Описание:
ChIP-seq for the Identification of Functional Elements in the Human Genome.- Identification of Candidate Functional Elements in the Genome from ChIP-seq Data.- GRO-seq, A Tool for Identification of Transcripts Regulating Gene Expression.-NanoCAGE: A Method for the Analysis of Coding and Non-coding 5'-capped Transcriptomes.- Deep Cap Analysis of Gene Expression (CAGE): Genome-Wide Identification of Promoters, Quantification of their Activity Andtranscriptional Network Inference.- Deep-RACE: Comprehensive Search for Novel ncRNAs Associated to a Specific Locus.- In silico Prediction of RNA Secondary Structure.- Computational Prediction of RNA-Protein Interactions.- Isolation of Nuclear RNA-Associated Protein Complexes.- Identification of Long Non-Coding RNAs Associated to Human Disease Susceptibility.- Targeting Promoter-associated RNAs by siRNAs.- RNA-FISH to Study Regulatory RNA at the Site of Transcription.- Detection and Characterization of R Loop Structures.- Induction of Transcriptional Gene Silencing by Expression of shRNA Directed to c-Myc P2 Promoter in Hepatocellular Carcinoma by Tissue Specific Virosomal Delivery.- Targeting Promoter Associated Non-coding RNA In Vivo.- Manipulation of Promoter-Associated Noncoding RNAs in Mouse Early Embryos for Controlling Sequence-Specific Epigenetic Status.


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