Описание: Young Middle Easterners describe their experiences with the region's laws and cultural mores, including the crime of holding hands before marriage and young women fighting for education. Beautifully written and profoundly moving, these stories present a decisive call for change at a crucial point in the evolution of the Middle East.
Experts consider how the lessons of World War I can help prevent U.S.--China conflict.
A century ago, Europe's diplomats mismanaged the crisis triggered by the murder of Archduke Franz Ferdinand of Austria and the continent plunged into World War I, which killed millions, toppled dynasties, and destroyed empires. Today, as the hundredth anniversary of the Great War prompts renewed debate about the war's causes, scholars and policy experts are also considering the parallels between the present international system and the world of 1914. Are China and the United States fated to follow in the footsteps of previous great power rivals? Will today's alliances drag countries into tomorrow's wars? Can leaders manage power relationships peacefully? Or will East Asia's territorial and maritime disputes trigger a larger conflict, just as rivalries in the Balkans did in 1914?
In The Next Great War?, experts reconsider the causes of World War I and explore whether the great powers of the twenty-first century can avoid the mistakes of Europe's statesmen in 1914 and prevent another catastrophic conflict. They find differences as well as similarities between today's world and the world of 1914 -- but conclude that only a deep understanding of those differences and early action to bring great powers together will likely enable the United States and China to avoid a great war.
Contributors Alan Alexandroff, Graham Allison, Richard N. Cooper, Charles S. Maier, Steven E. Miller, Joseph S. Nye Jr., T. G. Otte, David K. Richards, Richard N. Rosecrance, Kevin Rudd, Jack Snyder, Etel Solingen, Arthur A. Stein, Stephen Van Evera
Автор: Bruzzone, Catherine Название: Spanish on the move for kids ISBN: 0071456899 ISBN-13(EAN): 9780071456890 Издательство: McGraw-Hill Рейтинг: Цена: 1604.00 р. Наличие на складе: Поставка под заказ.
Описание: Introduces children to the Spanish language. This 45-minute CD features 22 songs while exposing them to Spanish language basics. It highlights key words and phrases, reinforcing important vocabulary for young listeners; and each song is followed by a game or activity that gives kids the opportunity to show off what they have learned.
Описание: Be prepared for your next job interview with this tried-and-true advice In today's tight job market, competition for programming jobs is hotter than ever. This third edition of a popular guide to the programming interviews includes new code examples, information on the latest languages, new chapters on sorting and design patterns, tips on using LinkedIn, and a downloadable app to help prepare applicants for the interview. Like its earlier editions, this guide covers what software companies and IT departments want their programmers to know and includes plenty of helpful hints to boost your confidence. Looks at current job search and hiring processes, such as the rise of LinkedIn and other social networks as recruiting resources Addresses the most important languages for a programmer to know and features examples in multiple languages Includes new programming questions designed to sharpen your knowledge Features all-new chapters on design patterns and sorting, including how to deal with memory constraints and mobility issues Walk into your next job interview with confidence, knowing you have thoroughly studied this newest edition of Programming Interviews Exposed.
A comprehensive overview of the new business context for biopharma companies, featuring numerous case studies and state-of-the-art marketing models
Biotechnology has developed into a key innovation driver especially in the field of human healthcare. But as the biopharma industry continues to grow and expand its reach, development costs are colliding with aging demographics and cost-containment policies of private and public payers. Concurrently, the development and increased affordability of sophisticated digital technologies has fundamentally altered many industries including healthcare. The arrival of new information technology (infotech) companies on the healthcare scene presents both opportunities and challenges for the biopharma business model. To capitalize on new digital technologies from R&D through commercialization requires industry leaders to adopt new business models, develop new digital and data capabilities, and partner with innovators and payers worldwide.
Written by two experts, both of whom have had decades of experience in the field, this book provides a comprehensive overview of the new business context and marketing models for biotech companies. Informed by extensive input by senior biotech executives and leading consultancies serving the industry, it analyzes the strategies and key success factors for the financing, development, and commercialization of novel therapeutic products, including strategies for engagement with patients, physicians and healthcare payers. Throughout case studies provide researchers, corporate marketers, senior managers, consultants, financial analysts, and other professionals involved in the biotech sector with insights, ideas, and models.
JACQUALYN FOUSE, PhD, RETIRED PRESIDENT AND CHIEF OPERATING OFFICER, CELGENE
"Biotech companies have long been innovators, using the latest technologies to enable cutting edge science to help patients with serious diseases. This book is essential to help biotech firms understand how they can-and must-apply the newest technologies including disruptive ones, alongside science, to innovate and bring new value to the healthcare system."
BRUCE DARROW, MD, PhD, CHIEF MEDICAL INFORMATION OFFICER, MOUNT SINAI HEALTH SYSTEM
"Simon and Giovannetti have written an essential user's manual explaining the complicated interplay of the patients who deserve cutting-edge medical care, the biotechnology companies (big and small) creating the breakthroughs, and the healthcare organizations and clinicians who bridge those worlds."
EMMANUEL BLIN, FORMER CHIEF STRATEGY OFFICER AND SENIOR VICE PRESIDENT, BRISTOL-MYERS SQUIBB
"If you want to know where biopharma is going, read this book Our industry is facing unprecedented opportunities driven by major scientific breakthroughs, while transforming itself to address accelerated landscape changes driven by digital revolutions and the emergence of value-based healthcare worldwide. In this ever-changing context, we all need to focus everything we do on the patients. They are why we exist as an industry, and this is ultimately what this insightful essay is really about."
JOHN MARAGANORE, PRESIDENT AND CHIEF EXECUTIVE OFFICER, ALNYLAM PHARMACEUTICALS
"Since the mapping of the human genome was completed nearly 15 years ago, the biotechnology industry has led the rapid translation of raw science to today's innovative medicines. However, the work does not stop in the lab. Delivering these novel medicines to patients is a complex and multifaceted process, which is elegantly described in this new book."
Описание: This book reviews current techniques used in membrane protein structural biology, with a strong focus on practical issues. The study of membrane protein structures not only provides a basic understanding of life at the molecular level but also helps in the rational and targeted design of new drugs with reduced side effects. Today, about 60% of the commercially available drugs target membrane proteins and it is estimated that nearly 30% of proteins encoded in the human genome are membrane proteins. In recent years much effort has been put towards innovative developments to overcome the numerous obstacles associated with the structure determination of membrane proteins. This book reviews a variety of recent techniques that are essential to any modern researcher in the field of membrane protein structural biology. The topics that are discussed are not commonly found in textbooks. The scope of this book includes: * Expression screening using fluorescent proteins * The use of detergents in membrane protein research * The use of NMR * Synchrotron developments in membrane protein structural biology * Visualisation and X-ray data collection of microcrystals * X-ray diffraction data analysis from multiple crystals * Serial millisecond crystallography * Serial femtosecond crystallography * Membrane protein structures in drug discovery The information provided in this book should be of interest to anyone working in the area of structural biology. Students will find carefully prepared overviews of basic ideas and advanced protein scientists will find the level of detail required to apply the material directly to their day to day work. Chapters 4, 5, 6, 8 and 9 of this book are published open access under a CC BY 4.0 license at link.springer.com.
Rapid technological developments have led to increasingly efficient sequencing approaches. Next Generation Sequencing (NGS) is increasingly common and has become cost-effective, generating an explosion of sequenced data that need to be analyzed. The skills required to apply computational analysis to target research on a wide range of applications that include identifying causes of cancer, vaccine design, new antibiotics, drug development, personalized medicine and higher crop yields in agriculture are highly sought after.
This invaluable book provides step-by-step guides to complex topics that make it easy for readers to perform essential analyses from raw sequenced data to answering important biological questions. It is an excellent hands-on material for teachers who conduct courses in bioinformatics and as a reference material for professionals. The chapters are written to be standalone recipes making it suitable for readers who wish to self-learn selected topics. Readers will gain skills necessary to work on sequenced data from NGS platforms and hence making themselves more attractive to employers who need skilled bioinformaticians to handle the deluge of data.
Описание: Next Generation Business Handbook offers strategies for the next generation of business success from the best business schools around the world. * Presents fresh ideas from the young, up--and--coming business thinkers and experts from the world`s best business schools.
Название: Microbiology and Infectious Diseases on the Move ISBN: 1444120123 ISBN-13(EAN): 9781444120127 Издательство: Taylor&Francis Рейтинг: Цена: 3673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Delivers everything the undergraduate medical student needs to know to understand the basics of microbiology and infectious diseases and get through their exams, in an attractive and highly accessible format
Описание: A practical framework for revenue-boosting supply chain management Next Generation Demand Management is a guidebook to next generation Demand Management, with an implementation framework that improves revenue forecasts and enhances profitability.
Автор: Isbister Katherine Название: How Games Move Us: Emotion by Design ISBN: 0262034263 ISBN-13(EAN): 9780262034265 Издательство: MIT Press Рейтинг: Цена: 2189.00 р. Наличие на складе: Нет в наличии.
Описание:
This is a renaissance moment for video games -- in the variety of genres they represent, and the range of emotional territory they cover. But how do games create emotion? In " How Games Move Us," Katherine Isbister takes the reader on a timely and novel exploration of the design techniques that evoke strong emotions for players. She counters arguments that games are creating a generation of isolated, emotionally numb, antisocial loners. Games, Isbister shows us, can actually play a powerful role in creating empathy and other strong, positive emotional experiences; they reveal these qualities over time, through the act of playing. She offers a nuanced, systematic examination of exactly how games can influence emotion and social connection, with examples -- drawn from popular, indie, and art games -- that unpack the gamer's experience.
Isbister describes choice and flow, two qualities that distinguish games from other media, and explains how game developers build upon these qualities using avatars, non-player characters, and character customization, in both solo and social play. She shows how designers use physical movement to enhance players' emotional experience, and examines long-distance networked play. She illustrates the use of these design methods with examples that range from Sony's "Little Big Planet" to the much-praised indie game "Journey "to art games like Brenda Romero's "Train."
Isbister's analysis shows us a new way to think about games, helping us appreciate them as an innovative and powerful medium for doing what film, literature, and other creative media do: helping us to understand ourselves and what it means to be human.
Professor Pippy P. Poopypants may be the greatest scientific genius the world has ever known. Unfortunately, he has such a silly name that nobody takes him seriously! He`s been laughed out of every major university in the world.
In fact, the only place that`ll hire him is Jerome Horwitz Elementary School. Hopefully, nobody at the school will laugh at his name (or make a comic book about him)....
...Because if just one more person makes fun of Poopypants, it might just drive him OFF THE DEEP END!
Needless to say, George and Harold poo-poo Poopypants`s pride -- practically pulverizing it to pieces -- and, hence, Poopypants is preparing to pounce!
Step up to witness a brief encounter of the cottony kind. This looks exactly like a job for The Amazing CAPTAIN UNDERPANTS!
Jorge y Berto no son malos chicos. Lo que pasa es que les gusta animar las cosas de vez en cuando. Asi, sin proponerselo, estan a punto de hacer que el profesor Pipicaca, un cientifico enloquecido y sin escrupulos que se encuentra a bordo de un robot gigantesco, se apodere del planeta entero. Quien desbaratara los perversos planes de Pipicaca? Un nuevo trabajo para el Capitan Calzoncillos!
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