Genomic Disorders, Lupski

Автор: Birch
Название: Surgical Disorders of the Peripheral Nerves
ISBN: 1848821077 ISBN-13(EAN): 9781848821071
Издательство: Springer
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Цена: 34799.00 р.
Наличие на складе: Поставка под заказ.

Описание: Since the highly praised first edition of Surgical Disorders of the Peripheral Nerves was published in 1998, greater understanding of the the molecular and cellular events which underlie the response of nerves to injury, regeneration and neuropathic pain has been achieved.

Автор: Lupski
Название: Genomic Disorders. 2006
ISBN: 1588295591 ISBN-13(EAN): 9781588295590
Издательство: Springer
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Цена: 10760.00 р. 15372.00 -30%
Наличие на складе: Есть (1 шт.)
Описание: A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.

Автор: Picken MD, PhD, FASN
Название: Amyloid and Related Disorders
ISBN: 1607613883 ISBN-13(EAN): 9781607613886
Издательство: Springer
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Цена: 26552.00 р.
Наличие на складе: Поставка под заказ.

Описание: Abnormal proteins are known to be associated with various pathologies. Most notably, these include amyloidoses, monoclonal protein deposits associated with plasma cell dyscrasia/multiple myeloma, cryoglobulins and various related organized and non-organized deposits. Amyloid and Related Disorders presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central nervous system, soft tissue and bone marrow pathology is covered. This approach provides a unifying concept of these pathologic processes, which have systemic involvement, and which have, hitherto, not been universally appreciated. Awareness of these diseases among a wider audience of pathologists may increase the rate of their diagnosis as well as that of earlier diagnosis. This volume will be invaluable to specialized and general pathologists as well as cytopathologists; other medical professionals may also benefit from this concise update on the systemic amyloidoses.

Автор: Ackermann
Название: Metabolic Influences on Risk for Tendon Disorders
ISBN: 3319339419 ISBN-13(EAN): 9783319339412
Издательство: Springer
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Цена: 23757.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book will be of considerable interest to students, practitioners (Doctors, Physiotherapists, and other health care professionals), and researchers who deal with the complex structure of tendons and the need to effectively address tendon disorders. The book is divided into three sections: (1) Basic Biology and Biochemical Markers; (2) Metabolic Disorders; and (3) Novel Therapies. The first section, devoted to the basic biology of tendons, is aimed at those individuals who want to gain basic information on tendons and the subsection on biochemical markers is chiefly aimed at researchers who are developing new studies within this field. The section on metabolic disorders is mainly directed at practitioners who desire to know how metabolic disorders can affect tendons in order to optimize treatment for their patients. Finally, the section on novel therapies is focused on some new treatment options within this field, and discussions regarding how management of tendon disorders needs to incorporate perspectives on current understanding of tendon metabolism.