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Metastasis of Colorectal Cancer, Beauchemin


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Автор: Beauchemin
Название:  Metastasis of Colorectal Cancer
ISBN: 9789400732933
Издательство: Springer
Классификация: ISBN-10: 9400732937
Обложка/Формат: Paperback
Страницы: 416
Вес: 0.60 кг.
Дата издания: 2010
Серия: Cancer Metastasis - Biology and Treatment/14
Язык: English
Размер: 234 x 156 x 22
Ссылка на Издательство: Link
Поставляется из: Германии
Описание: Introduction; N. Beauchemin, J. Huot 1. The Metastatic Process: an Overview; N.Porquet, S. Guot, J. Huot 1.1 Models of metastasis - 1.1.1 The progression model - 1.1.2 The transient compartment model - 1.1.3 The early oncogenesis model - 1.1.4 The fusion model - 1.1.5 The gene transfer models - 1.1.6 The genetic predisposition model 1.2 Metastatic steps - 1.2.1 Development of the primary colorectal cancer - 1.2.1.1 Initiation of the primary neoplasm - 1.2.1.2 Influence of stromal cells - 1.2.1.3 Influence of the extracellular matrix - 1.2.1.4 Epithelial-Mesenchymal transition - 1.2.1.5 Angiogenesis and lymphangiogenesis - 1.2.2 Intravasation - 1.2.3 Circulation of cancer cells - 1.2.4 Extravasation - 1.2.4.1 The adhesion on endothelial cells and the homing concept of metastasis - 1.2.4.2 The passage across the endothelium 1.2.5 Colonization of the secondary sites 1.3 Concluding Remarks References 2. Physiopathology of Colorectal Metastasis; C. Ferrario, M. Basik 2.1 Mechanisms of metastatic spread - 2.1.1 Circulatory spread - 2.1.1.1 Lymphatic spread - 2.1.1.2 Hematogenous spread - 2.1.2 Local spread - 2.1.3 Tumour dormancy 2.2 Sites of metastasis and consequences of spread - 2.2.1 Liver - 2.2.1.1 Steps in liver invasion - 2.2.1.2 Development of liver failure - 2.2.2 Lungs - 2.2.3 Peritoneum - 2.2.4 Bone and bone marrow - 2.2.5 Brain metastasis 2.3 factors contributing to metastatic spread - 2.3.1 Tumour factors - 2.3.1.1 Tissue Factor - 2.3.1.2 EGFR - 2.3.2 Host factors - 2.3.2.1 Immunity - 2.3.2.2 Diet, exercise and liver disease - 2.3.3 Iatrogenic factors 2.4 Conclusion References 3. The Genetic of Colorectal Cancer; A.M. Kaz, W.M. Grady 3.1 Introduction 3.2 The Adenoma-to-Carcinoma Sequence 3.3 Genomic Instability - 3.3.1 Overview - 3.3.2 Chromosome Instability - 3.3.3 DNA Mismatch Repair Inactivation and Microsatellite Instability - 3.3.4 Base Excision Repair Defects/MYH 3.4 Common Deregulated Signalling Pathways - 3.4.1 Wingless/Wnt Signalling Pathway - 3.4.1.1 APC - 3.4.1.2 B-Catenin (CTNNB1) - 3.4.2 KRAS, BRAF and RAS-RAF-MAPK Signalling Pathway - 3.4.2.1 K-RAS - 3.4.2.2 BRAF - 3.4.3 p53 (TP53) - 3.4.4 The Phosphatidylinositol 3-kinase (PI3K) Pathway - 3.4.4.1 PIK3CA - 3.4.4.2 PTEN - 3.4.5 TGF-B Signalling Pathways - 3.4.5.1 TGFBR2 - 3.4.5.2 The SMAD Family of Genes - 3.4.5.3 TGF-B Superfamily Receptors: ACVR2 and BMPR1A 3.5 Genome-Wide Analyses of Colorectal Cancer Genes 3.6 Metastasis Genes 3.7 Conclusions References 4. Epigenetics of Colorectal Cancer; F.J. Carmona, M. Esteller 4.1 Introduction 4.2 DNA methylation defects in colorectal cancer - 4.2.1 Hypomethylation of DNA 4.3 Inactivation of tumour suppressor genes by CpG island hypermethylation 4.4 Epigenetic regulation of microRNA in cancer 4.5 MicroRNAs as metastasis switches 4.6 Histone modification defects in colon cancer 4.7 Epigenetic contribution to co


Colorectal Surgery ,

Автор: H. Randolph Bailey
Название: Colorectal Surgery ,
ISBN: 1437717241 ISBN-13(EAN): 9781437717242
Издательство: Elsevier Science
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Цена: 16713.00 р. 23875.00 -30%
Наличие на складе: Есть (1 шт.)
Описание: Suitable for the general surgeon who is called upon to manage diseases and disorders of the large bowel, rectum, and anus, this title provides advanced guidance on how to avoid complications and achieve the successful results.

Early Diagnosis and Treatment of Cancer Series: Colorectal Cancer: Expert Consult: Online and Print

Автор: Gearhart
Название: Early Diagnosis and Treatment of Cancer Series: Colorectal Cancer: Expert Consult: Online and Print
ISBN: 1416046860 ISBN-13(EAN): 9781416046868
Издательство: Elsevier Science
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Цена: 13102.00 р. 18717.00 -30%
Наличие на складе: Есть (1 шт.)
Описание: Each volume in the "Early Detection and Treatment of Cancer Series" is packed with practical, authoritative information designed to cover the full range of diagnostic procedures, including pathologic, radiologic, bronchoscopic, and surgical aspects. You'll be able to determine the safest, shortest, least invasive way to reach an accurate diagnosis; stage the disease; and, choose the best initial treatment for early stages. Based on current evidence in the literature, authors provide clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging s udies are needed to diagnose and stage each type of cancer.

Practical, authoritative, and highly-illustrated, this volume in the brand new "Early Detection and Treatment of Cancer" series covers current protocols and the latest advances in diagnostic imaging and molecular and serologic markers for colon cancer. Apply expert advice on the best 'next-step' plan for different presentations and tips for less invasive protocols. Get clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed for accurate diagnosis and staging.

Clear figures, tables, and boxes illustrate step-by-step care of the full range of problems encountered. Better manage your patients with procedural video clips and more on the included CD-ROM. The small size and convenient format make this an ideal purchase for diagnostic reference.

Signal Transduction in Cancer Metastasis

Автор: Wen-Sheng Wu; Chi-Tan Hu
Название: Signal Transduction in Cancer Metastasis
ISBN: 9400733585 ISBN-13(EAN): 9789400733589
Издательство: Springer
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Цена: 27951.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book examines the signal mechanisms responsible for triggering a series of phenotypical changes of primary tumor which may lead to final colonization of the tumor in a second home. It highlights the initial stage of tumor metastasis.

Cancer Metastasis and the Lymphovascular System:

Автор: Stanley P. L. Leong
Название: Cancer Metastasis and the Lymphovascular System:
ISBN: 1489991026 ISBN-13(EAN): 9781489991027
Издательство: Springer
Рейтинг:
Цена: 27950.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Sentinel lymph node (SLN) procedures have opened a window of opportunity for the study of micrometastasis. In eighty percent (80%) of metastasis there lies an orderly pattern of progression via the lymphatic network, while 20% of the time systemic metastasis occurs, bypassing the lymphatic system. During the past two decades, significant progress has been achieved in understanding the anatomical, functional, cellular and molecular aspects of the lymphovascular system and the metastasis process. · Molecular imaging advances help to localize early cancers more precisely. · Current status of the immune responses in the draining lymph nodes against cancer is summarized. · New paradigms of early cancer growth, proliferation, overcoming apoptosis are exploited in the development of anticancer treatment. In this book, basic scientists and clinicians exchange ideas so that laboratory findings can be applied to clinical dilemmas, and clinical problems can be targeted for research in the laboratory.

Lymphangiogenesis in Cancer Metastasis

Автор: Steven A. Stacker; Marc G. Achen
Название: Lymphangiogenesis in Cancer Metastasis
ISBN: 940073042X ISBN-13(EAN): 9789400730427
Издательство: Springer
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Цена: 32004.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The book covers all aspects of the new field of lymphatic vessel growth from the fundamental role that protein growth factors and their receptors play in lymphangiogenesis to the potential application of these advances to cancer diagnosis and treatment.

Metastasis of Colorectal Cancer

Автор: Beauchemin
Название: Metastasis of Colorectal Cancer
ISBN: 9048188326 ISBN-13(EAN): 9789048188321
Издательство: Springer
Рейтинг:
Цена: 28734.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book covers colon cancer metastasis from fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, and more.

Colorectal Tumors: Atlas of Large Section Histopathology

Автор: Tibor Tot
Название: Colorectal Tumors: Atlas of Large Section Histopathology
ISBN: 3131405910 ISBN-13(EAN): 9783131405913
Издательство: Thieme Verlagsgruppe
Цена: 21470.00 р.
Наличие на складе: Поставка под заказ.

Описание: Large-section histopathology widens your perspectives...Correct diagnosis and staging are essential in determining the appropriate therapy of colorectal carcinoma, one of the most common malignancies in America and Europe. As medical science continues to develop rapidly, histopathology remains an essential part of diagnosis in most malignant diseases. In this era of interdisciplinary medicine, the role of pathology has expanded to provide images that easily correlate with endoscopic, radiological, or operative findings.In this remarkable atlas, Tibor Tot presents colon pathology in large histological sections, with cross-sections of entire tumors in their anatomic environments and their circumferential surgical margins. These unique images form a guide to diagnosis, tumor typing and staging according to TNM criteria. They help to assess the completeness of a surgical excision and to understand the heterogeneity of colorectal carcinomas. Features:- Cases illustrated in two-page spreads with clinical information, conventional histopathology, and large-section histology images enlarged to almost a full page. - Pathology seen in the context of surrounding tissues- The margins of malignant tumors visible in their entirety- Schematic guides to interpretation of the large-section images - Emphasis on diagnostic advantages of using large section technique- Technical guidelines for obtaining large-section histopathology specimensThis atlas is the result of seven years of studying almost 2,000 cases of colorectal carcinoma and other intestinal lesions and is highly recommended for pathologists, radiologists, surgeons, and oncologists alike.

Mcgraw-hill manual colorectal surgery

Автор: Kaiser, Andreas M.
Название: Mcgraw-hill manual colorectal surgery
ISBN: 0071590706 ISBN-13(EAN): 9780071590709
Издательство: McGraw-Hill
Рейтинг:
Цена: 10637.00 р.
Наличие на складе: Поставка под заказ.

Описание: McGraw Hill`s Manual of Colorectal Surgery is the perfect day-to-day resource if you`re a doctor who treats patients suffering from colon cancer, as well as problems like hemorrhoids and Crohn`s Disease.

Multidisciplinary Management of Liver Metastases in Colorectal Cancer

Автор: Qin
Название: Multidisciplinary Management of Liver Metastases in Colorectal Cancer
ISBN: 9401777535 ISBN-13(EAN): 9789401777537
Издательство: Springer
Рейтинг:
Цена: 20962.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book focuses on early diagnosis and multidisciplinary treatment, which is the key to preventing the occurrence of the liver metastases in colorectal cancer, and to increasing the resection rate of the liver metastasis foci and the 5-year survival after surgery. This book is divided into five parts: the introduction, basics, diagnosis, treatment and prevention. It has 20 chapters in total, covering the latest advances in colorectal cancer liver metastases epidemiology, pathogenesis, molecular diagnostics, marker screening, imaging technology, surgery, chemotherapy and prevention, etc. It provides professionals with up-to-date and comprehensive information on colorectal liver metastases. This book is relevant for senior surgeons and physicians working in oncology, general surgery, chemotherapy, digestive medicine, liver medicine and hepatic surgery.

Colorectal surgery

Автор: Mackay, G J(ed)et Al
Название: Colorectal surgery
ISBN: 0199571775 ISBN-13(EAN): 9780199571772
Издательство: Oxford Academ
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Цена: 7126.00 р.
Наличие на складе: Поставка под заказ.

Описание: An essential revision tool for general surgical trainees preparing for the FRCS examination, and in particular those declaring colorectal surgery as an area of special interest, this handbook provides easy access to relevant, up-to-date information in a portable format that can be used at work or for study.


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