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MACPF/CDC Proteins - Agents of Defence, Attack and Invasion, Anderluh


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Цена: 27950.00р.
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Автор: Anderluh
Название:  MACPF/CDC Proteins - Agents of Defence, Attack and Invasion
ISBN: 9789401788809
Издательство: Springer
Классификация:



ISBN-10: 9401788804
Обложка/Формат: Hardback
Страницы: 323
Вес: 0.83 кг.
Дата издания: 2014
Серия: Subcellular Biochemistry/80
Язык: English
Издание: 2014 ed.
Иллюстрации: 5 tables, black and white; 52 illustrations, color; 5 illustrations, black and white; xi, 329 p. 57 illus., 52 illus. in color.; 5 tables, black and white; 52 illustrations, color; 5 illustrations, black and white; xi, 329 p. 57 illus., 52 illus. in
Размер: 234 x 155 x 23
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein super family that was originally discovered because of unexpected structural similarity between a domain present in bacterial cholesterol-dependent cytolysins (CDC) and proteins of the membrane attack complex/perforin (MACPF) family. Members of the MACPF/CDC super family are crucial for many biological processes, being efficient agents of development, defence, attack and invasion of cells and tissues. However, their best-known role is in bacterial pathogenesis and the proper functioning of the vertebrate immune system, via formation of transmembrane pores in target cell membranes. The book contains chapters on the distribution of MACPF/CDC proteins and on aspects of their evolution and structural properties, the similarities between different super family members and functional properties of some of the best known examples. The book also contains an overview of biophysical approaches that may be used in the future to provide further insights into how these interesting proteins function.
Дополнительное описание: Part I: Overview of MACPF/CDCs.- Introduction: Brief Historical Overview.- Distribution of MACPF/CDC proteins.- Evolution of the Complement System.- Part II: Structures of MACPF/CDCs.- Structural Features of Cholesterol Dependent Cytolysins and Comparison



MACPF/CDC Proteins - Agents of Defence, Attack and Invasion

Автор: Gregor Anderluh; Robert Gilbert
Название: MACPF/CDC Proteins - Agents of Defence, Attack and Invasion
ISBN: 9402403396 ISBN-13(EAN): 9789402403398
Издательство: Springer
Рейтинг:
Цена: 27950.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein super family that was originally discovered because of unexpected structural similarity between a domain present in bacterial cholesterol-dependent cytolysins (CDC) and proteins of the membrane attack complex/perforin (MACPF) family. Members of the MACPF/CDC super family are crucial for many biological processes, being efficient agents of development, defence, attack and invasion of cells and tissues. However, their best-known role is in bacterial pathogenesis and the proper functioning of the vertebrate immune system, via formation of transmembrane pores in target cell membranes. The book contains chapters on the distribution of MACPF/CDC proteins and on aspects of their evolution and structural properties, the similarities between different super family members and functional properties of some of the best known examples. The book also contains an overview of biophysical approaches that may be used in the future to provide further insights into how these interesting proteins function.


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