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Molecular mechanisms and physiology of disease, Maulik


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Цена: 32142.00р.
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Автор: Maulik
Название:  Molecular mechanisms and physiology of disease
ISBN: 9781493907052
Издательство: Springer
Классификация:





ISBN-10: 1493907050
Обложка/Формат: Hardback
Страницы: 1060
Вес: 1.16 кг.
Дата издания: 2014
Язык: English
Издание: 2014 ed.
Иллюстрации: 21 tables, black and white; 33 illustrations, color; 10 illustrations, black and white; xiv, 505 p. 43 illus., 33 illus. in color.
Размер: 234 x 155 x 33
Читательская аудитория: Professional & vocational
Подзаголовок: Implications for epigenetics and health
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes including DNA methylation and chromatin post-translational modifications including potential interventions with DNA methyltransferase inhibitors and histone deacetylase inhibitors are explored in initial chapters. These provide a detailed overview and important background to the entire field. The book is then focussed on epigenetic mechanisms involved in various diseases including anti-inflammatory and autoimmune conditions. Important accounts relating to the effects of epigenetics in metabolic syndrome, cardiovascular disease and asthma are the focus of subsequent chapters. The role of epigenetic dysregulation in malignancy is a current topic of interest and represents an intense field of research. A large component of this book is dedicated to the analysis of aberrant epigenetic processes in carcinogenesis and cancer progression. Further, chapters are focused on emerging cancer prevention using nutritional components and anti-cancer therapies particularly with histone deacetylase inhibitors, which have already been approved for the treatment of cutaneous T-cell lymphoma. The emerging role of nanoparticle preparations, especially in the context of delivering potential epigenetic therapies to target cells in various diseases, is also explored in this book. Overall, this book encompasses a wide range of topics related to epigenetic mechanisms in health and disease and would appeal to anyone with an interest in epigenetics, chromatin biology and emerging epigenetic interventions and therapies.
Дополнительное описание: Epigenetics in Childhood Health and Disease.- Role of Epigenetics in Neural Differentiation: Implications for Health and Disease.- An Overview of Epigenetic Mechanisms in Health and Disease.- Epigenetics: Role of Histone Proteases in Cellular Functions an



Biochemistry and  Molecular Biology,  5 edition

Автор: Snape Alison
Название: Biochemistry and Molecular Biology, 5 edition
ISBN: 0199609497 ISBN-13(EAN): 9780199609499
Издательство: Oxford Academ
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Цена: 6651.00 р.
Наличие на складе: Есть (1 шт.)
Описание: The ideal text for any bioscience student encountering biochemistry and molecular cell biology for the first time. Exceptionally clear explanations, frequent diagrams, and a user-friendly design and layout ensure that the text provides a perfect introduction to this complex yet fascinating subject area.

Essential Molecular Biology V1

Автор: Brown
Название: Essential Molecular Biology V1
ISBN: 0199636427 ISBN-13(EAN): 9780199636426
Издательство: Oxford Academ
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Цена: 9425.00 р. 13464.00 -30%
Наличие на складе: Есть (1 шт.)
Описание: This text is a guide to the basic techniques needed for molecular biology. It concentrates on the preparation, purification and handling of nucleic acids.

Cellular Signal Processing: An Introduction to the Molecular Mechanisms of Signal Transduction

Автор: Friedrich Marks, Ursula Klingmuller, Karin Muller- Decker
Название: Cellular Signal Processing: An Introduction to the Molecular Mechanisms of Signal Transduction
ISBN: 0815345348 ISBN-13(EAN): 9780815345343
Издательство: Taylor&Francis
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Цена: 11023.00 р.
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Описание:

Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.

Conformational proteomics of macromolecular architecture: approaching the structure of large molecular assemblies and their mechanisms of action (with cd-rom)

Название: Conformational proteomics of macromolecular architecture: approaching the structure of large molecular assemblies and their mechanisms of action (with cd-rom)
ISBN: 9812386149 ISBN-13(EAN): 9789812386144
Издательство: World Scientific Publishing
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Цена: 13622.00 р.
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Описание: Biological processes involving large macromolecular assemblies are thought to be a dynamic consequence of cooperativity and metastability. The folding of a peptide chain creates local environments from which "activity" can emerge. In the same way, the assembly of large molecular complexes creates dynamic features that would only be feasible in a large construct.

The biological implications of such adaptation will be explored as it applies to the static quasisymmetry situations, as well as to the dynamics of structural transitions. The current wealth of solved high-resolution complex structures makes this an appropriate time to summarize the state of the art in structural dynamics of living architectures. With contributions by leading scientists in the fields of virology, bacterial flagellum, cytoskeleton, ribosome and giant enzymes, this work presents knowledge in the various fields of structural proteomics of very large molecular assemblies, with focus on their mechanisms of action.

Protein Misfolding, Aggregation and Conformational Diseases / Part B: Molecular Mechanisms of Conformational Diseases

Автор: Uversky Vladimir N., Fink Anthony
Название: Protein Misfolding, Aggregation and Conformational Diseases / Part B: Molecular Mechanisms of Conformational Diseases
ISBN: 038736529X ISBN-13(EAN): 9780387365299
Издательство: Springer
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Цена: 36570.00 р.
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Описание: The second volume continues to fill the gap in protein review and protocal literature while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. The focus of Part B is the molecular basis of differential disorders.

Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease

Автор: Tony Harris
Название: Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease
ISBN: 9400796161 ISBN-13(EAN): 9789400796164
Издательство: Springer
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Цена: 28732.00 р.
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Описание: Cell-cell adhesion is fundamental for the development and homeostasis of animal tissues and organs. * How do cadherins and catenins interact to assemble AJs and mediate adhesion? * How do AJs interface with other cellular machinery to couple adhesion with the whole cell? * How do AJs affect cell behaviour and multicellular development?


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