Описание: Intends to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. This book emphasizes on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target.
Автор: Robert Crichton Название: Biological Inorganic Chemistry, ISBN: 0444537821 ISBN-13(EAN): 9780444537829 Издательство: Elsevier Science Цена: 8310 р. Наличие на складе: Поставка под заказ.
Описание: Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Second Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems. Beginning with an overview of metals and selected nonmetals in biology, the book then discusses the following concepts: basic coordination chemistry for biologists; structural and molecular biology for chemists; biological ligands for metal ions; intermediary metabolism and bioenergetics; and methods to study metals in biological systems. The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment.
Автор: James House Название: Inorganic Chemistry, ISBN: 0123851106 ISBN-13(EAN): 9780123851109 Издательство: Elsevier Science Рейтинг: Цена: 8310 р. Наличие на складе: Поставка под заказ.
Описание: Inorganic Chemistry, Second Edition, provides essential information for students of inorganic chemistry or for chemists pursuing self-study. The presentation of topics is made with an effort to be clear and concise so that the book is portable and user friendly. The text emphasizes fundamental principles—including molecular structure, acid-base chemistry, coordination chemistry, ligand field theory, and solid state chemistry. It is organized into five major themes (structure, condensed phases, solution chemistry, main group and coordination compounds) with several chapters in each. There is a logical progression from atomic structure to molecular structure to properties of substances based on molecular structures, to behavior of solids, etc. The textbook contains a balance of topics in theoretical and descriptive chemistry. For example, the hard-soft interaction principle is used to explain hydrogen bond strengths, strengths of acids and bases, stability of coordination compounds, etc. Discussion of elements begins with survey chapters focused on the main groups, while later chapters cover the elements in greater detail. Each chapter opens with narrative introductions and includes figures, tables, and end-of-chapter problem sets. This new edition features new and improved illustrations, including symmetry and 3D molecular orbital representations; expanded coverage of spectroscopy, instrumental techniques, organometallic and bio-inorganic chemistry; and more in-text worked-out examples to encourage active learning and to prepare students for their exams. This text is ideal for advanced undergraduate and graduate-level students enrolled in the Inorganic Chemistry course. This core course serves Chemistry and other science majors. The book may also be suitable for biochemistry, medicinal chemistry, and other professionals who wish to learn more about this subject area.
Автор: Hanessian Stephen Название: Natural Products in Medicinal Chemistry ISBN: 3527332189 ISBN-13(EAN): 9783527332182 Издательство: Wiley Рейтинг: Цена: 19250 р. Наличие на складе: Поставка под заказ.
Описание: The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past deca
Описание: Explores the way in which peptides, proteins, nucleic acids and carbohydrates use therapeutically. With help of illustrations, this book covers both compounds and how therapeutics exert their influence through an understanding of biological processes.
Описание: There is a need explain that generic versions of a drug may not be manufactured by the same process as brand-name drugs and that the different processes may have dramatically different environmental impacts. Two global forces are at odds today—the push for "greener" processes and the push for lower drug prices. This book brings this conflict into sharp focus by discussing in detail the published process chemistry for top-selling small molecule drugs.
Providing insights about process route selection, choice of reagents, and reaction conditions, Pharmaceutical Process Chemistry for Synthesis guides process chemists in identifying best processes for manufacturing these blockbuster drugs as they lose patent protection. Further, it highlights the strategies and methodology that might be useful for expediting the process research and development of the blockbusters of the future.
Written from a refreshingly objective perspective, this book is essential for process chemists who need to devise practical syntheses for increasingly complex drugs in a constantly decreasing time frame.
Автор: Sessler, Jonathan L.; Doctrow, Susan R.; McMurry, Название: Medicinal Inorganic Chemistry (Hardback) ISBN: 0841238995 ISBN-13(EAN): 9780841238992 Издательство: Oxford Academ Рейтинг: Цена: 9176 р. Наличие на складе: Поставка под заказ.
Описание: This book reviews the current diagnostic and therapeutic uses of metal-containing compounds in medicine, as well as the role of metals in disease.
Описание: Inorganic Chemistry for Geochemistry and Environmental Sciences: Fundamentals and Applications discusses the structure, bonding and reactivity of molecules and solids of environmental interest, bringing the reactivity of non-metals and metals to inorganic chemists, geochemists and environmental chemists from diverse fields.
Название: Biological inorganic chemistry ISBN: 1891389432 ISBN-13(EAN): 9781891389436 Издательство: Springer Рейтинг: Цена: 10971 р. Наличие на складе: Поставка под заказ.
Описание: Gives both an overview of biological inorganic chemistry and presents a detailed look at metal-ion containing biological systems. This comprehensive guide to biological inorganic chemistry aims to serve both as a course text for advanced undergraduates and postgraduates and as a reference text for those working in this area.
Автор: Nogrady, Thomas; Weaver, Donald F. Название: Medicinal Chemistry ISBN: 0195104560 ISBN-13(EAN): 9780195104561 Издательство: Oxford Academ Рейтинг: Цена: 7532 р. Наличие на складе: Поставка под заказ.
Описание: Fully updated, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centred approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular modeling techniques, and new clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.
Автор: Cotton, F.albert Wilkinson, Sir Geoffrey Murillo, Название: Advanced inorganic chemistry ISBN: 0471199575 ISBN-13(EAN): 9780471199571 Издательство: Wiley Рейтинг: Цена: 23238 р. Наличие на складе: Поставка под заказ.
Описание: This edition incorporates many chemical developments, particularly theoretical advances in the interpretation of bonding and reactivity in inorganic compounds. It systematically covers the periodic table and encompasses the chemistry of all chemical elements and their compounds.
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