Handbook of Safety Assessment of Nanomaterials: From Toxicological Testing to Personalized Medicine, Fadeel Bengt
Автор: Simeonova P.P., Opopol N., Luster M.I. Название: Nanotechnology - Toxicological Issues and Environmental Safety ISBN: 1402060750 ISBN-13(EAN): 9781402060755 Издательство: Springer Рейтинг: Цена: 10971 р. Наличие на складе: Поставка под заказ.
Описание: Nanotechnology is one of the fastest growing technological fields of the 21st century. Nanotechnologies will impact numerous industries, including daily consumer products, health care, energy, and transportation. However, the success of the emerging nanotechnology applications will depend on dynamic development of nanomaterial toxicology, risk and exposure assessment. Little is known about the potential adverse health and ecological effects of exposure to engineered nanomaterials, the main components of many nanotechnologies. Concerns are coming from the initial toxicological studies as well as the research and epidemiological reports on ultrafine particle toxicity. This book provides a summary of the state-of-art knowledge on nanomaterials and nanoparticles – toxicological issues; risk assessment and control measures; public participation and educational/ethical issues; and lastly, institutional mechanisms and status reports from various countries. This book includes a summary of the most important gaps in knowledge, needs for research, and collaborations in the field of nanotechnology regarding safe application and development.
Автор: Simeonova P.P., Opopol N., Luster M.I. Название: Nanotechnology - Toxicological Issues and Environmental Safety ISBN: 1402060742 ISBN-13(EAN): 9781402060748 Издательство: Springer Рейтинг: Цена: 24140 р. Наличие на складе: Поставка под заказ.
Описание: Nanotechnology is one of the fastest growing technological fields of the 21st century. Nanotechnologies will impact numerous industries, including daily consumer products, health care, energy, and transportation. However, the success of the emerging nanotechnology applications will depend on dynamic development of nanomaterial toxicology, risk and exposure assessment. Little is known about the potential adverse health and ecological effects of exposure to engineered nanomaterials, the main components of many nanotechnologies. Concerns are coming from the initial toxicological studies as well as the research and epidemiological reports on ultrafine particle toxicity. This book provides a summary of the state-of-art knowledge on nanomaterials and nanoparticles – toxicological issues; risk assessment and control measures; public participation and educational/ethical issues; and lastly, institutional mechanisms and status reports from various countries. This book includes a summary of the most important gaps in knowledge, needs for research, and collaborations in the field of nanotechnology regarding safe application and development.
Автор: Couvreur Patrick & Mura Simona Название: Nanotheranostics For Personalized Medicine ISBN: 981471352X ISBN-13(EAN): 9789814713528 Издательство: World Scientific Publishing Рейтинг: Цена: 17530 р. Наличие на складе: Поставка под заказ.
Описание: The application of nanotechnology in the biomedical field, known as nanomedicine, has gained much interest in the recent past as a versatile strategy for selective drug delivery and diagnostic purposes. The nanotheranostic approach, which aims to combine both therapeutic and imaging/diagnostic functionalities, is characterized by a strong pluridisciplinarity where the chemistry of materials, bioconjugate chemistry, pharmaceutical technology, drug delivery, imaging, and pharmacology, work together. Nanotheranostics combine simultaneous non-invasive diagnosis and treatment of diseases with the exciting possibility to monitor drug release and distribution in real time; thus offering the opportunity to optimize treatment outcomes in cancer and other severe diseases. Clinical applications of nanotheranostics would enable earlier detection and treatment of diseases, and earlier assessment of the response, thus allowing to identify patients which would potentially respond to therapy and have higher possibilities of a favorable outcome.Nanotheranostics for Personalized Medicine presents an integrated and transdisciplinary description of nanotheranostics. It provides principles of imaging techniques and concrete examples of advances and challenges in the development of nanotheranostics for personalized medicine.This book is written for students (Bachelors to Doctoral level) as well as experienced researchers, in academia or the industry, interested in this emerging concept in the nanomedicine field.
Описание: A comprehensive overview of the latest progress, trends, and the current state of this important and rapidly expanding field. Clearly and logically structured, the first part explores the fundamentals, while the second adopts a practical approach, discussing various applications.
Автор: Pan Название: Personalized Medicine with a Nanochemistry Twist ISBN: 3319335448 ISBN-13(EAN): 9783319335445 Издательство: Springer Рейтинг: Цена: 26985 р. Наличие на складе: Поставка под заказ.
Описание: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Автор: Georga, Eleni I. Название: Personalized Predictive Modelling in Type 1 Diabetes ISBN: 012804831X ISBN-13(EAN): 9780128048313 Издательство: Elsevier Science Рейтинг: Цена: 13745 р. Наличие на складе: Поставка под заказ.
Описание: Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or multivariate), (ii) regression technique (linear or non-linear), (iii) learning mechanism (batch or sequential), (iv) development and testing procedure and (v) scaling properties. In addition, simulation models of meal-derived glucose absorption and insulin dynamics and kinetics are covered, as an integral part of glucose predictive models. . This book will help engineers and clinicians to: select a regression technique which can capture both linear and non-linear dynamics in glucose metabolism in diabetes, and which exhibits good generalization performance under stationary and non-stationary conditions; ensure the scalability of the optimization algorithm (learning mechanism) with respect to the size of the dataset, provided that multiple days of patient monitoring are needed to obtain a reliable predictive model; select a features set which efficiently represents both spatial and temporal dependencies between the input variables and the glucose concentration; select simulation models of subcutaneous insulin absorption and meal absorption; identify an appropriate validation procedure, and identify realistic performance measures.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
