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A Practical Guide to Rational Drug Design, Sun Hongmao


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Цена: 24423.00р.
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Автор: Sun Hongmao
Название:  A Practical Guide to Rational Drug Design
ISBN: 9780081000984
Издательство: Elsevier Science
Классификация:

ISBN-10: 0081000987
Обложка/Формат: Hardback
Страницы: 208
Вес: 0.43 кг.
Дата издания: 01.10.2015
Язык: English
Размер: 226 x 155 x 18
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание: This book is not going to be an exhaustive survey covering all aspects of rational drug design. Instead, it is going to provide critical know-how through real-world examples. Relevant case studies will be presented and analyzed to illustrate the following: how to optimize a lead compound whether one has high or low levels of structural information; how to derive hits from competitors’ active compounds or from natural ligands of the targets; how to springboard from competitors’ SAR knowledge in lead optimization; how to design a ligand to interfere with protein-protein interactions by correctly examining the PPI interface; how to circumvent IP blockage using data mining; how to construct and fully utilize a knowledge-based molecular descriptor system; how to build a reliable QSAR model by focusing on data quality and proper selection of molecular descriptors and statistical approaches. A Practical Guide to Rational Drug Design focuses on computational drug design, with only basic coverage of biology and chemistry issues, such as assay design, target validation and synthetic routes.


The Organic Chemistry of Drug Design and Drug Action,

Автор: Richard B. Silverman
Название: The Organic Chemistry of Drug Design and Drug Action,
ISBN: 0123820308 ISBN-13(EAN): 9780123820303
Издательство: Elsevier Science
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Цена: 13304.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules.

This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage.

This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries.

Oxford Handbook of Practical Drug Therapy

Автор: Richards, Duncan; Aronson, Jeffrey; Reynolds, John
Название: Oxford Handbook of Practical Drug Therapy
ISBN: 0199562857 ISBN-13(EAN): 9780199562855
Издательство: Oxford Academ
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Цена: 5384.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This Handbook mirrors the leading national guides to prescribing. The safe and effective use of medicine requires a sound knowledge of pharmacology. As readers use this practical book, they will increase their knowledge.

Pharmaceutical Quality by Design: A Practical Appr oach

Автор: Schlindwein
Название: Pharmaceutical Quality by Design: A Practical Appr oach
ISBN: 1118895207 ISBN-13(EAN): 9781118895207
Издательство: Wiley
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Цена: 11238.00 р.
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Описание:

A practical guide to Quality by Design for pharmaceutical product development

Pharmaceutical Quality by Design: A Practical Approach outlines a new and proven approach to pharmaceutical product development which is now being rolled out across the pharmaceutical industry internationally. Written by experts in the field, the text explores the QbD approach to product development. This innovative approach is based on the application of product and process understanding underpinned by a systematic methodology which can enable pharmaceutical companies to ensure that quality is built into the product.

Familiarity with Quality by Design is essential for scientists working in the pharmaceutical industry. The authors take a practical approach and put the focus on the industrial aspects of the new QbD approach to pharmaceutical product development and manufacturing. The text covers quality risk management tools and analysis, applications of QbD to analytical methods, regulatory aspects, quality systems and knowledge management. In addition, the book explores the development and manufacture of drug substance and product, design of experiments, the role of excipients, multivariate analysis, and include several examples of applications of QbD in actual practice. This important resource:

  • Covers the essential information about Quality by Design (QbD) that is at the heart of modern pharmaceutical development
  • Puts the focus on the industrial aspects of the new QbD approach
  • Includes several illustrative examples of applications of QbD in practice
  • Offers advanced specialist topics that can be systematically applied to industry

Pharmaceutical Quality by Design offers a guide to the principles and application of Quality by Design (QbD), the holistic approach to manufacturing that offers a complete understanding of the manufacturing processes involved, in order to yield consistent and high quality products.

Fluid Catalytic Cracking Handbook: An Expert Guide to the Practical Operation, Design, and Optimization of FCC Units 3rd Edition

Автор: Reza Sadeghbeigi
Название: Fluid Catalytic Cracking Handbook: An Expert Guide to the Practical Operation, Design, and Optimization of FCC Units 3rd Edition
ISBN: 012386965X ISBN-13(EAN): 9780123869654
Издательство: Elsevier Science
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Цена: 25096.00 р.
Наличие на складе: Поставка под заказ.

Описание: Providing practical information and tools that engineers can use to maximize the profitability and reliability of their fluid catalytic cracking (FCC) operations, this book focuses on the developments, the shift to using FCC to process lower quality crudes, and on troubleshooting.

Oxford Handbook of Practical Drug Therapy

Автор: Richards, Duncan; Aronson, Jeffrey
Название: Oxford Handbook of Practical Drug Therapy
ISBN: 0198530072 ISBN-13(EAN): 9780198530077
Издательство: Oxford Academ
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Цена: 3483.00 р.
Наличие на складе: Поставка под заказ.

Описание: The Oxford Handbook of Practical Drug Therapy brings together for the first time in a single book practical information on safe prescribing with the background knowledge that underpins clinical pharmacology. It contains a series of monographs on approximately 250 of the drugs which students and junior doctors are likely to come into contact with, arranged broadly by therapeutic category (in line with the British National Formulary). Each monograph covers the following aspects of the drug concerned; pharmacological actions and potential uses; advice on usage for its major indications; side effects; interactions with other drugs; advice on monitoring the patient and what to tell the patient about the drug they are taking.


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