Автор: Trygve Tollefsbol Название: Handbook of Epigenetics, ISBN: 0123757096 ISBN-13(EAN): 9780123757098 Издательство: Elsevier Science Рейтинг: Цена: 19454 р. Наличие на складе: Поставка под заказ.
Описание:
Epigenetics is considered by many to be the "new genetics" because of the overwhelming evidence of the contribution of non-genetic factors such as nutrition, environment, and chemical exposure on gene expression. The effects of epigenetics are vast, including tissue/organ regeneration, X-chromosome inactivation, and stem cell differentiation and genomic imprinting and aging. Aberrations of epigenetics influence many diseases for which clinical intervention is already in place, and many novel epigenetic therapies for cancer, immune disorders, neurological and metabolic disorders, and imprinting diseases are on the horizon.
This comprehensive collection of reviews written by leaders in the field of epigenetics provides a broad view of this important and evolving topic. From molecular mechanisms and epigenetic technology to discoveries in human disease and clinical epigenetics, the nature and applications of the science will be presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders.
Contributions by leading international investigators involved in molecular research and clinical and therapeutic applications
Integrates methods and biological topics with basic and clinical discoveries
Includes coverage of new topics in epigenetics such as prions, regulation of long-term memory by epigenetics, metabolic aspects of epigenetics, and epigenetics of neuronal disorders
Автор: Francis Richard C. Название: Epigenetics: How Environment Shapes Our Genes ISBN: 039334228X ISBN-13(EAN): 9780393342284 Издательство: Wiley Рейтинг: Цена: 2358 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Goodbye, genetic blueprint. . . . The first book for general readers on the game-changing field of epigenetics.
Название: Epigenetics ISBN: 0520267095 ISBN-13(EAN): 9780520267091 Издательство: Wiley Рейтинг: Цена: 14883 р. Наличие на складе: Поставка под заказ.
Описание: Illuminating the processes and patterns that link genotype to phenotype, this title seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene.
Автор: Tollefsbol Trygve O. Название: Epigenetics Protocols ISBN: 158829336X ISBN-13(EAN): 9781588293367 Издательство: Springer Рейтинг: Цена: 23016 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A collection of state-of-the-art methods for epigenetic analysis, including recent breakthrough techniques that have great potential in the rapidly expanding field of non-Mendelian genetics. The authors provide techniques for the analysis of chromatin remodeling, such as histone acetylation and methylation. In addition, methods in newly developed and especially promising areas of epigenetics, such as telomere position effects, quantitative epigenetics, and ADP ribosylation are covered. There is also an updated analysis of techniques involving DNA methylation and its role in the modification, as well as the maintenance, of chromatin structure. Of special interest are potentially revolutionary techniques. These include methods for determining changes in native chromatin, methods of microarray analysis applied to epigenetics, and methylation-sensitive single-strand conformation techniques. The methods are suitable not only for studying fundamental biological processes, but also for investigating possible therapeutic interventions and such diseases as cancer.
Автор: Rozanov, Vsevolod Название: Stress and Epigenetics in Suicide ISBN: 012805199X ISBN-13(EAN): 9780128051993 Издательство: Elsevier Science Рейтинг: Цена: 6378 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Stress and Epigenetics in Suicidediscusses the central role of epigenetic modifications in suicidal behavior. As early-life stress and an individual's ability to cope with such stressors, combined with psychological factors, social factors, and existential and cognitive factors can predispose young people to suicidal behavior and put them at added risk of suicidal behavior later in life, this book provides readers with an overview of the neurobiology of stress, an introduction to the epigenetic changes induced by stress, and an understanding of how vulnerability and resilience to stress are built. . It integrates these mechanisms into a biobehavioral model of suicide based on epigenetic marks, gene-environment interactions, and other stressors. More importantly, it provides future direction for research and discusses potential interventions. . This book is an ideal and trusted resource for researchers and clinicians who are interested in learning how the environment can affect behavior through genetics, and for those seeking the development of new methods for suicide prevention.
Автор: Rousseaux Название: Epigenetics and Human Reproduction ISBN: 3642147720 ISBN-13(EAN): 9783642147722 Издательство: Springer Рейтинг: Цена: 30532 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction
Автор: Meyer Peter, Scanes G Colin, Luther , Название: Plant Epigenetics ISBN: 1405129778 ISBN-13(EAN): 9781405129770 Издательство: Wiley Рейтинг: Цена: 37571 р. Наличие на складе: Поставка под заказ.
Описание: With the discovery of RNAi pathways and the histone code, epigenetics has become a popular and fast evolving research topic. Plant science has made a number of elementary contributions to this field, and the common elements of epigenetic systems have linked research groups interested in plant, fungal and animal systems.
Автор: Trygve Tollefsbol Название: Transgenerational Epigenetics, ISBN: 0124059449 ISBN-13(EAN): 9780124059443 Издательство: Elsevier Science Рейтинг: Цена: 18414 р. Наличие на складе: Поставка под заказ.
Описание: Transgenerational Epigenetics provides a comprehensive analysis of the inheritance of epigenetic phenomena between generations. Recent research points to the existence of biological phenomena that are controlled not through gene mutations, but rather through reversible and heritable epigenetic processes. . Epidemiological studies have suggested that environmental factors may be heritable. In fact, environmental factors often play a role in transgenerational epigenetics, which may have selective or adverse effects on the offspring. This epigenetic information can be transferred through a number of mechanisms including DNA methylation, histone modifications or RNA and the effects can persist for multiple generations. . This book examines the evolution of epigenetic inheritance, its expression in animal and plant models, and how human diseases, such as metabolic disorders and cardiovascular diseases, appear to be affected by transgenerational epigenetic inheritance. It discusses clinical interventions in transgenerational epigenetic inheritance that may be on the horizon to help prevent diseases before the offspring are born, or to reduce the severity of diseases at the very earliest stages of development in utero, and current controversies in this area of study, as well as future directions for research.
Автор: Zdenko Herceg Название: Epigenetics and Cancer, Part B,71 ISBN: 0123808642 ISBN-13(EAN): 9780123808646 Издательство: Elsevier Science Рейтинг: Цена: 20345 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Genes interact with the environment, experience, and biology of the brain to shape an animal’s behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.
Автор: Zdenko Herceg Название: Epigenetics and Cancer, Part A,70 ISBN: 0123808669 ISBN-13(EAN): 9780123808660 Издательство: Elsevier Science Рейтинг: Цена: 20345 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Genes interact with the environment, experience, and biology of the brain to shape an animal’s behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.
Автор: Edith Heard Название: Epigenetics and Development,104 ISBN: 0124160271 ISBN-13(EAN): 9780124160279 Издательство: Elsevier Science Рейтинг: Цена: 23760 р. Наличие на складе: Поставка под заказ.
Описание: This new volume of Current Topics in Developmental Biology covers epigenetics and development, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as epigenetic marking of the zebrafish developmental program, functions of DNA methylation and hydroxymethylation in mammalian development, and reprogramming and the pluripotent stem cell cycle.
Автор: Francis Richard Название: Epigenetics ISBN: 0393070050 ISBN-13(EAN): 9780393070057 Издательство: Wiley Рейтинг: Цена: 3628 р. Наличие на складе: Поставка под заказ.
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