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Medical Epigenetics, Trygve Tollefsbol



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Цена: 20633р.
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Автор: Trygve Tollefsbol
Название:  Medical Epigenetics
Перевод названия: Тригве Толлефсбол: Медицинская эпигенетика
ISBN: 9780128032398
Издательство: Elsevier Science
Классификация:
ISBN-10: 0128032391
Обложка/Формат: Hardback
Страницы: 560
Вес: 2.806 кг.
Дата издания: 12.07.2016
Серия: Life Sciences
Язык: English
Иллюстрации: Illustrations
Размер: 225 x 283 x 50
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
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Поставляется из: Англии
Описание:

Medical Epigenetics is an inclusive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic disease that affect these systems, and modes of treating epigenetic-based disorders and diseases. This book provides stand-alone coverage of all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. It is useful not only to physicians, nurses, medical students, and many others directly involved with healthcare, but also investigators in life sciences, biotech companies, graduate students, and all others who are interested in more applied aspects of epigenetics.

The expansion of the field of epigenetics has brought a wealth of information with respect to variations in phenotypes that are heritable. In addition, many advances have emerged that have shown epigenetic aberrations as central to a number of diseases and disorders that were previously thought to be manifested primarily through genetic factors. Along with the remarkable studies that have been made in our understanding of epigenetic-based diseases and disorders has come new information that allows treatments that target these many epigenetic aberrations. Medical Epigenetics brings all of this knowledge together to comprehensively review the state of medical epigenetics in one defining volume.

The basic design of Medical Epigenetics is to lead the reader from the fundamental mechanisms of epigenetics as they apply to humans through approaches for treating epigenetic-based diseases. This book begins with the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics. Medical Epigenetics closes with a chapter on future prospects in medical epigenetics. This book is by far the most complete book in the area of applied epigenetics.
Focuses on practical and applied aspects of medical epigeneticsIncludes peer-reviewed chapters with up-to-date coverage of emerging topics in medical epigenetics by leading expertsAppeals to those interested in fundamental epigenetics and inheritance, as well as those with more clinical interests including practicing physicians and other health care professionalsCovers the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics




Epigenetics: How Environment Shapes Our Genes

Автор: Francis Richard C.
Название: Epigenetics: How Environment Shapes Our Genes
ISBN: 039334228X ISBN-13(EAN): 9780393342284
Издательство: Wiley
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Цена: 2058 р.
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Описание: Goodbye, genetic blueprint. . . . The first book for general readers on the game-changing field of epigenetics.

Epigenetics and Human Reproduction

Автор: Rousseaux
Название: Epigenetics and Human Reproduction
ISBN: 3642147720 ISBN-13(EAN): 9783642147722
Издательство: Springer
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Цена: 28734 р.
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Описание: Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Translating Epigenetics to the Clinic

Автор: Laurence, Jeffrey
Название: Translating Epigenetics to the Clinic
ISBN: 0128008024 ISBN-13(EAN): 9780128008027
Издательство: Elsevier Science
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Цена: 10642 р.
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Описание: Translating Epigenetics to the Clinic reviews current methodological tools and experimental approaches used by leading translational researchers seeking to use epigenetics as a clinical model. It organizes epigenetics into disease treatment areas with a major focus on oncology, and with much coverage of pervasive treatment categories such as diabetes, as well as the ‘diseases of modernity’—including pharmacological addiction, dementia, and ageing. . Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. The book promotes cross-disciplinary communication between the sub-specialties of medicine. In common with the rest of the books in Translational Medicine, the book remains unified in theme by emphasizing recent innovations, critical barriers to progress, and the new tools being used to overcome them. Also includes specific areas of research that require additional study to advance the field as a whole.

Stress and Epigenetics in Suicide

Автор: Rozanov, Vsevolod
Название: Stress and Epigenetics in Suicide
ISBN: 012805199X ISBN-13(EAN): 9780128051993
Издательство: Elsevier Science
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Цена: 6354 р.
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Описание: Stress and Epigenetics in Suicidediscusses the central role of epigenetic modifications in suicidal behavior. As early-life stress and an individual's ability to cope with such stressors, combined with psychological factors, social factors, and existential and cognitive factors can predispose young people to suicidal behavior and put them at added risk of suicidal behavior later in life, this book provides readers with an overview of the neurobiology of stress, an introduction to the epigenetic changes induced by stress, and an understanding of how vulnerability and resilience to stress are built. . It integrates these mechanisms into a biobehavioral model of suicide based on epigenetic marks, gene-environment interactions, and other stressors. More importantly, it provides future direction for research and discusses potential interventions. . This book is an ideal and trusted resource for researchers and clinicians who are interested in learning how the environment can affect behavior through genetics, and for those seeking the development of new methods for suicide prevention.

Epigenetics and Neuroendocrinology

Автор: Spengler
Название: Epigenetics and Neuroendocrinology
ISBN: 331929900X ISBN-13(EAN): 9783319299006
Издательство: Springer
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Цена: 22359 р.
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Описание: The field of neuroendocrinology has extended from the initial interest in the hypothalamic control of pituitary secretion to embrace multiple reciprocal interactions between the central nervous system (CNS) and endocrine systems in the coordination of homeostasis and various physiological responses from adaptation to disease. Most recently, epigenetic mechanisms were recognized for their role in the development of the neuroendocrine axes as well as in the mediation of gene-environment interactions in stress-related psychiatry disorders.

Personalized Epigenetics

Автор: Trygve Tollefsbol
Название: Personalized Epigenetics
ISBN: 0124201350 ISBN-13(EAN): 9780124201354
Издательство: Elsevier Science
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Цена: 12709 р.
Наличие на складе: Невозможна поставка.

Описание:

Personalized Epigenetics discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy.

The book details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, and noncoding RNA, and the diagnostic, prognostic, and therapeutic potential of the field, it also reviews the impact of the environment on epigenetic variations among individuals and the role of pharmacology and drug development in personalized epigenetics.

Most importantly, the text covers personalized epigenetics from a disease-oriented perspective, presenting chapters that provide advances in widespread disorders or diseases, including diabetes, cancer, autoimmune disorders, obesity, cardiovascular diseases, neurological disorders, and pain management.

Handbook of Epigenetics,

Автор: Trygve Tollefsbol
Название: Handbook of Epigenetics,
ISBN: 0123757096 ISBN-13(EAN): 9780123757098
Издательство: Elsevier Science
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Цена: 17551 р.
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Описание:

Epigenetics is considered by many to be the "new genetics" because of the overwhelming evidence of the contribution of non-genetic factors such as nutrition, environment, and chemical exposure on gene expression. The effects of epigenetics are vast, including tissue/organ regeneration, X-chromosome inactivation, and stem cell differentiation and genomic imprinting and aging. Aberrations of epigenetics influence many diseases for which clinical intervention is already in place, and many novel epigenetic therapies for cancer, immune disorders, neurological and metabolic disorders, and imprinting diseases are on the horizon.

This comprehensive collection of reviews written by leaders in the field of epigenetics provides a broad view of this important and evolving topic. From molecular mechanisms and epigenetic technology to discoveries in human disease and clinical epigenetics, the nature and applications of the science will be presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders.


  • Contributions by leading international investigators involved in molecular research and clinical and therapeutic applications
  • Integrates methods and biological topics with basic and clinical discoveries
  • Includes coverage of new topics in epigenetics such as prions, regulation of long-term memory by epigenetics, metabolic aspects of epigenetics, and epigenetics of neuronal disorders
Handbook of Epigenetics

Автор: Tollefsbol, Trygve
Название: Handbook of Epigenetics
ISBN: 0128053887 ISBN-13(EAN): 9780128053881
Издательство: Elsevier Science
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Цена: 24040 р.
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Описание: Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue and organ regeneration, X-chromosome inactivation, stem cell differentiation, genomic imprinting, and aging. . The first edition of this important work received excellent reviews; the second edition continues its comprehensive coverage adding more current research and new topics based on customer and reader reviews, including new discoveries, approved therapeutics, and clinical trials. From molecular mechanisms and epigenetic technology, to discoveries in human disease and clinical epigenetics, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics, to therapeutic interventions for epigenetic-based disorders.


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