Автор: Martin, Ricky Название: Me ISBN: 0451234154 ISBN-13(EAN): 9780451234155 Издательство: Random House - Penguin Цена: 1848.00 р. Наличие на складе: Поставка под заказ.
Описание: International superstar, Ricky Martin, who has sold more than 60 million albums worldwide, opens up for the first time about memories of his early childhood, experiences in the famed boy band Menudo, struggles with his identity during the Livin' la Vida Loca phenomenon, reflections on coming to terms with his sexuality, relationships that allowed him to embrace love, and life-changing decisions like devoting himself to helping children around the world and becoming a father. "Me" is an intimate memoir about the very liberating and spiritual journey of one of the most iconic pop-stars of our time.
Описание: Best friends always stick together -- especially when they are in trouble Ricky Ricotta and his Mighty Robot always watch out for each other -- that's what friends are for This time, they've managed to mangle the Ricotta family's minivan. Somehow they have to find a way to make up for their mistake. When a mean little Martian named Major Monkey invades Earth, Ricky and his Robot race to save the day once more. But Major Monkey has a plan to get rid of Ricky's Robot so that no one will be able to stop him Now it's up to Ricky to rescue his friend and keep Major Monkey from menacing mousekind
Автор: Johnstone Ricky Название: Cell Death Techniques:: A Laboratory Manual ISBN: 162182005X ISBN-13(EAN): 9781621820055 Издательство: NBN International Рейтинг: Цена: 12461.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Regulated cell death, which is involved in nearly every aspect of animal development and physiology, can be challenging to study in the laboratory. There are multiple types of cell death, several interconnected signaling pathways can be activated, and the postmortem consequences may vary. Therefore, a combination of specialized techniques is often required to characterize and confirm cell death in the system of interest. This laboratory manual provides a comprehensive suite of step-by-step protocols for inducing, detecting, visualizing, characterizing, and quantifying cell death in a variety of systems. The contributors describe strategies for identifying and evaluating the biochemical and morphological changes that occur during apoptosis, autophagy, necrosis, and other forms of cell death, as well as for pinpointing the genes and proteins that may be involved. The protocols employ flow cytometry, imaging and microscopy, RNAi, western blotting, enzymatic activity measurements, and other tools to assess phenomena such as DNA fragmentation, lysosomal membrane permeabilization, autophagic flux, apoptosome or ripoptosome formation, caspase activation, and cytochrome c release. Techniques are described for both in vitro systems and in vivo models, including mice, C. elegans, and Drosophila. The authors also provide guidance on interpreting and presenting the results of cell death experiments, as well as advice on complementary procedures that may be required to confirm the results of a given experiment. This indispensable laboratory resource will enable all cell and developmental biologists, from the graduate level upward, to confidently carry out and comprehend a wide array of cell viability assays.
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