Drug Transporters: Volume 1: Role and Importance in Adme and Drug Development, Nicholls Glynis, Youdim Kuresh, Fox David

Автор: Nicholls Glynis, Youdim Kuresh, Fox David
Название: Drug Transporters: Volume 2: Recent Advances and Emerging Technologies
ISBN: 1782628665 ISBN-13(EAN): 9781782628668
Издательство: Royal Society of Chemistry
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Цена: 33581.00 р.
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Описание: This book comprehensively reviews current knowledge and techniques in the transporter sciences and their relations to drug metabolism and pharmacokinetics.

Автор: Nicholls Glynis, Youdim Kuresh, Fox David
Название: Drug Transporters: Role and Importance in Adme and Drug Development Complete Set
ISBN: 1782628673 ISBN-13(EAN): 9781782628675
Издательство: Royal Society of Chemistry
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Цена: 63360.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Understanding and quantifying the effects of membrane transporters within the human body is essential for modulating drug safety and drug efficacy. This two volume set of books comprehensively reviews current knowledge and techniques in the transporter sciences and their relations to drug metabolism and pharmacokinetics. The second volume is specifically dedicated to emerging science and technologies, highlighting potential areas for future advances within the drug transporter field. The topics covered in this set of books ensure that all relevant aspects of transporters are described across the drug development process, from in silico models and preclinical tools through to the potential impact of transporters in the clinic. Contributions are included from expert leaders in the field, at-the-bench industrial scientists, renowned academics and international regulators. Case studies and emerging developments are highlighted, together with the merits and limitations of the available methods and tools, and extensive references to reviews on specific in-depth topics are also included for those wishing to pursue their knowledge further. As such, this text serves as an essential handbook of information for postgraduate students, academics, industrial scientists and regulators who wish to understand the role of transporters in absorption, distribution, metabolism, and excretion processes. In addition, it is also a useful reference tool on the models and calculations necessary to predict their effect on human pharmacokinetics and pharmacodynamics.