Resistance to Tyrosine Kinase Inhibitors, Daniele Focosi

Автор: Neel
Название: Protein Tyrosine Phosphatases in Cancer
ISBN: 1493936476 ISBN-13(EAN): 9781493936472
Издательство: Springer
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Цена: 23508.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book aims to bridge the gap in understanding how protein-tyrosine phosphatases (PTPs), which carry out the reverse reaction of tyrosine phosphorylation, feature in cancer cell biology. The expertly authored chapters will first review the general features of the PTP superfamily, including their overall structure and enzymological properties; use selected examples of individual PTP superfamily members, to illustrate emerging data on the role of PTPs in cancer; and will review the current status of PTP-based drug development efforts.

Автор: Ward
Название: STAT Inhibitors in Cancer
ISBN: 3319429477 ISBN-13(EAN): 9783319429472
Издательство: Springer
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Цена: 22203.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume, which includes contributions from leading scientists and clinicians in the field, provides definitive, state-of-the-art information on STAT inhibitors in a biological and clinical context. It gives an overview of the biology of the STAT family of transcription factors and their role in cancer etiology. Additionally, it describes the raft of therapeutic approaches being used to inhibit STATs in the context of various cancers, covering the full spectrum of therapeutic approaches to inhibiting STATs, and presenting emerging data from clinical trials.