Nanomedicine for Cancer Therapy, Piyush Kumar; Rohit Srivastava
Автор: Mishra Название: Nanomedicine for Drug Delivery and Therapeutics ISBN: 1118414098 ISBN-13(EAN): 9781118414095 Издательство: Wiley Рейтинг: Цена: 20507.00 р. 29296.00-30% Наличие на складе: Есть (1 шт.) Описание: This book describes a broad area of nanomedicine which involves mainly applications, diseases, and diagnostics. The comprehensive coverage provides researchers, academics, and health specialists with a great tool, that includes techniques applicable to various uses.
Автор: Edmund C. Lattime Название: Gene Therapy of Cancer, ISBN: 0123942950 ISBN-13(EAN): 9780123942951 Издательство: Elsevier Science Рейтинг: Цена: 23244.00 р. Наличие на складе: Поставка под заказ.
Описание: Gene therapy as a treatment for cancer is at a critical point in its evolution. This book offers a comprehensive assessment of the field including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells.
Автор: Steven Gray Название: Epigenetic Cancer Therapy ISBN: 0128002069 ISBN-13(EAN): 9780128002063 Издательство: Elsevier Science Рейтинг: Цена: 17517.00 р. Наличие на складе: Поставка под заказ.
Описание:
Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector.
The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver).
The book encompasses both large-scale intergovernmental initiatives as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer.
Автор: Nimesh, Surendra Название: Advances in Nanomedicine for the Delivery of Therapeutic Nucleic ISBN: 0081005571 ISBN-13(EAN): 9780081005576 Издательство: Elsevier Science Рейтинг: Цена: 28633.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance.
The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc.
Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies
Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc.
Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field
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