Fernando Monje-Casas; Ethelvina Queralt Badia The Mitotic Exit Network 9781493965007

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Автор: Fernando Monje-Casas; Ethelvina Queralt Badia
Название: The Mitotic Exit Network
ISBN: 9781493965007
Издательство: Springer
Классификация:

Клеточная биология (цитология)

ISBN-10: 149396500X
Обложка/Формат: Hardback
Страницы: 281
Вес: 0.75 кг.
Дата издания: 2017
Серия: Methods in molecular biology
Язык: English
Издание: 1st ed. 2017
Иллюстрации: 22 tables, color; 24 illustrations, color; 11 illustrations, black and white; x, 281 p. 35 illus., 24 illus. in color.
Размер: 188 x 264 x 19
Читательская аудитория: Professional & vocational
Подзаголовок: Methods and protocols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This detailed book collects the main methodologies used for the analysis of the activity, localization, and regulation of the components of the Mitotic Exit Network (MEN) pathway during mitotic exit in Saccharomyces cerevisiae, as well as for the evaluation of the roles of these proteins in other cellular processes, such as the condensation of the rDNA, the functionality of the mitotic checkpoints, and cytokinesis. Budding yeast serves as an ideal model system for dissecting the mechanisms that regulate cell cycle progression and providing new insights into the molecular basis of cell cycle control and, thus, into the origin of diseases that arise as a consequence of problems during cell division. Therefore, although this volume concentrates on Saccharomyces cerevisiae as a model, it also details the implications that the research about the MEN have on our understanding of the mitotic exit process in higher eukaryotes. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, The Mitotic Exit Network: Methods and Protocols will be a valuable reference for cellular and molecular biologists and biochemists as well as for all scientists interested in the study of the regulation of mitotic exit using budding yeast as a model organism.

Дополнительное описание: Regulation of Mitotic Exit in Saccharomyces cerevisiae.- Methods of Synchronization of Yeast Cells for the Analysis of Cell Cycle Progression.- Analysis of Cell Cycle Progression in Saccharomyces cerevisiae Using the Budding Index and Tubulin Staining.- D

The Mitotic Exit Network, Fernando Monje-Casas; Ethelvina Queralt Badia