Описание: In this unique presentation of a revolutionary field of science, the first section introduces the domains of application for genomics and bioinformatics, such as sequencing and the comparative sequence analysis of model organisms, investigating genetically influenced diseases, the development of new active substances, agri--food and environmental genomics. There then follows an overview of current topics central to DNA technologies, proteomics, metabolomics and bioinformatics, including such hot topics as DNA chip fabrication, yeast two hybrid analysis, tools for gene expression studies, metabolic networks and systems biology. The whole is rounded off by four chapters on the ethical, legal and social aspects of this sensitive topic.
Автор: M Cuperlovic-Culf Название: NMR Metabolomics in Cancer Research, ISBN: 1907568840 ISBN-13(EAN): 9781907568848 Издательство: Elsevier Science Рейтинг: Цена: 30443 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, the book begins with an examination of the cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis. Chapters in the latter part of the book look at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field.
Автор: B C Weimer Название: Metabolomics in Food and Nutrition, ISBN: 1845695127 ISBN-13(EAN): 9781845695125 Издательство: Elsevier Science Рейтинг: Цена: 22127 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Metabolomics enables valuable information about the biochemical composition of foods to be rapidly obtained. Since the biochemical profile of food largely determines key food properties such as flavour and shelf life, the information gained using metabolomics-based methods will enable greater control of food quality and also help to determine the relationship between diet and health. Metabolomics in food and nutrition provides an overview of their current and potential use in the food industry.Part one reviews equipment, methods and data interpretation in metabolomics including the use of nuclear magnetic resonance (NMR), statistical methods in metabolomics, and metabolic reconstruction databases and their application to metabolomics research. Part two explores applications of metabolomics in humans, plants and food. Chapters discuss metabolomics in nutrition, human samples for health assessments, and current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications. Further chapters highlight metabolomic analysis of plants and crops, metabolomics for the safety assessment of genetically modified (GM) crops, and applications of metabolomics in food science including food composition and quality, sensory and nutritional attributes.With its distinguished editors and team of expert contributors, Metabolomics in food and nutrition is a technical resource for industrial researchers in the food and nutrition sectors interested in the potential of metabolomics methods and academics and postgraduate students working in the area.
Описание: Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation.
Автор: Tomita M., Nishioka T. Название: Metabolomics / The Frontier of Systems Biology ISBN: 4431251219 ISBN-13(EAN): 9784431251217 Издательство: Springer Рейтинг: Цена: 22204 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Metabolism is the sum of the chemical reactions in cells that produce life-sustaining chemical energy and metabolites. In the post-genome era, metabolism has taken on new significance for biological scientists: metabolites are the chemical basis of phenotypes that are final expressions of genomic information. This book covers research on metabolomics, ranging from the development of specialized chemical analytical techniques to the construction of databases and methods for metabolic simulation. The authors have been directly involved in the development of all the subject areas, including capillary electrophoresis, liquid chromatography, mass spectrometry, metabolic databases, and metabolic simulation. Breakthrough achievements and the future of metabolome studies are described, making this book a valuable source for researchers in metabolomics in diverse fields, such as plant, animal, cellular, microbial, pharmaceutical, medical, and genetic sciences.
Автор: Nikolau Basil J., Wurtele Eve Syrkin Название: Concepts in Plant Metabolomics ISBN: 1402056079 ISBN-13(EAN): 9781402056079 Издательство: Springer Рейтинг: Цена: 34007 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A guide for practitioners of metabolomics. Metabolomics has the potential of defining cellular processes as it provides a measure of ultimate phenotype of an organism, as defined by the collage of small molecules, whose levels of accumulation is altered in response to genetic and environmentally induced changes in gene expression.
Автор: Saito K., Dixon R.A., Willmitzer L. Название: Plant Metabolomics ISBN: 3540297812 ISBN-13(EAN): 9783540297819 Издательство: Springer Рейтинг: Цена: 38858 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Metabolomics - which deals with all metabolites of an organism - plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology. Written by leading researchers, this volume gives a comprehensive coverage of this field.
Автор: Weckwerth Wolfram Название: Metabolomics / Methods and Protocols ISBN: 1588295613 ISBN-13(EAN): 9781588295613 Издательство: Springer Рейтинг: Цена: 27471 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Metabolomics, the identification and quantification of all metabolites in a biological sample, focuses on different GC/MS techniques and their applications to real world samples. This includes the analysis of blood samples, plant metabolite analysis and mass spectral and retention time index libraries of known and unknown metabolites, and more.
Описание: Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.
Описание: Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. Currently in its 67th volume, the series features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. This thematic volume features reviews on metabolomics coming of age with its technological diversity.
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