Biomedical EPR - Part A focuses on applications of EPR spectroscopy in the areas of free radicals, metals, medicine, and physiology. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field which lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR.
Key Features: Free Radicals in Medicine
Radicals in vivo and in Model Systems, and their Study by Spin Trapping
In vivo EPR, including Oximetry and Imaging
Time Domain EPR at Radio Frequencies
EPR of Copper Complexes: Motion and Frequency Dependence
Time Domain EPR and Electron Spin Echo Envelope Modulation
Описание: EPR of Free Radicals in Solids: Trends in Methods and Applications presents methods and applications of modern EPR for the study of free radical processes in solids, which so far are only available in the journal literature. The first part of the book, covering trends in methods, contains experimentally oriented chapters on continuous wave and pulsed EPR techniques and special methods involving muon magnetic resonance and optical detection and theory for dynamic studies. New simulation schemes, including the influence of dynamics, are presented as well as advances in the calculation of hyperfine and electronic g-tensors. The second part of the book presents applications involving studies of radiation and photo-induced inorganic and organic radicals in inert matrices, including novel results of quantum effects in small radicals. High-spin molecules and complexes are also considered as well as radical processes in photosynthesis. Recent advances in EPR dosimetry are summarized.
Описание: This volume takes two approaches to this topic - (1) illustrating the general principles outlined above through a series of different stem cell examples - embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations.
Автор: Halliwell Название: Free Radicals in Biology & Medicine ISBN: 0198500440 ISBN-13(EAN): 9780198500445 Издательство: Oxford Academ Цена: 7128 р. Наличие на складе: Нет в наличии.
Описание: Since the publication of the second edition of "Free Radicals in Biology and Medicine" in 1989 the techniques of modern molecular, cellular, and structural biology have provided new data that have transformed scientific thinking about topics within free radical research. Reactive species, such as peroxynitrite, have been discovered to have a role in biological systems. Therefore much of the third edition has been completely rewritten and what remains from the second has been thoroughly updated. There are new chapters on antioxidant defence systems in bacteria, plants, and animals; the detection of free radicals; the role of antioxidants in ageing, nutrition, disease, and therapy; and a new appendix on molecular biology. The chapter on oxidative stress and its consequences includes the damage and repair of DNA, proteins, and lipids, cytokines, and cell death (both apoptosis and necrosis). Free radicals and other reactive species are now implicated in a wide range and number of diseases and the third edition covers their role in hypertension, diabetes, lung damage, cystic fibrosis, nervous system disorders, viral infections, and cancer. This book is intended for postgraduate researchers, academics, industrial scientists, clinicians, and medical workers in chemistry, biochemistry and biomedical fields.
Автор: Halliwell, Barry; Gutteridge, John Название: Free Radicals in Biology and Medicine ISBN: 019856869X ISBN-13(EAN): 9780198568698 Издательство: Oxford Academ Рейтинг: Цена: 11088 р. Наличие на складе: Нет в наличии.
Описание: Provides coverage of isoprostanes and related compounds, mechanisms of oxidative damage to DNA and proteins (and the repair of such damage), the free radical theory of ageing and the roles played by reactive species in signal transduction, cell death, human reproduction, and other important biological events.
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