Maley Frontiers in Cancer Research 9781493964581

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Автор: Maley
Название: Frontiers in Cancer Research
ISBN: 9781493964581
Издательство: Springer
Классификация:

Онкология

Фармакология

ISBN-10: 1493964585
Обложка/Формат: Hardback
Страницы: 258
Вес: 0.57 кг.
Дата издания: 2016
Язык: English
Иллюстрации: 11 black & white illustrations, 17 colour illustrations, biography
Размер: 234 x 156 x 16
Читательская аудитория: General (us: trade)
Основная тема: Biomedicine
Подзаголовок: Evolutionary Foundations, Revolutionary Directions
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This is the ideal book for anyone contemplating starting a career in, or shifting their career to, studying the dynamics that drive cancer progression and its response to therapy. Topics include the theory and population genetics of cancers, genetic diversity within tumors (intra-tumor heterogeneity), understanding how mutant clones expand in tissues, the role of cancer stem cells in the dynamics of tumors, the evolution of metastasis, and how to improve cancer therapy by addressing the evolution of cancers in response to our interventions. There are also chapters on the patterns of cancer susceptibility in humans due to a mismatch between our modern environment and the environment in which our ancestors evolved, as well as a chapter on the evolution of cancer suppression mechanisms that have evolved in different species, particularly the large long-lived animals like elephants and whales that are better at suppressing cancers than humans.

This book serves as a primer on the evolutionary and ecological theory of cancer- the framework upon which all the details of cancer may be hung. It is ideal for oncologists and cancer researchers interested in evolutionary theory, and evolutionary biologists and ecologists interested in gaining insights into cancer development and prevention.

Дополнительное описание: 1. The Evolutionary Foundations of Cancer Research.- 2. The Role of Theory in Cancer Research.- 3. Population Genetics of Neoplasms.- 4. Diversity in Neoplasms.- 5. How do Mutant Clones Expand in Normal Tissue?.- 6. Cancer Stem Cells in Tumor Evolution.-

Frontiers in Cancer Research, Maley