Wang Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification 9783662533970

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Автор: Wang
Название: Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification
ISBN: 9783662533970
Издательство: Springer
Классификация:

Биохимия

Белки

Нанотехнология

Биохимическая инженерия

Биотехнологии

ISBN-10: 3662533979
Обложка/Формат: Hardback
Страницы: 96
Вес: 0.34 кг.
Дата издания: 2016
Серия: Springer Theses
Язык: English
Издание: 1st ed. 2016
Иллюстрации: 30 tables, color; 41 illustrations, color; 5 illustrations, black and white; xiii, 96 p. 46 illus., 41 illus. in color.
Размер: 234 x 156 x 8
Читательская аудитория: Professional & vocational
Основная тема: Chemistry
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This thesis focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of “affinity guided covalent conjugation.” This newly established methodology provides complementary resolution to protein labeling, imaging and trafficking. By systematically investigating the coordination interaction between protein and quantum dots using various engineered protein ligands, this thesis proposes a general rule for protein self-assembly on the surface of quantum dots and reports a revolutionized nanobelt protein in accordance with this rule. It is an extraordinary example of interdisciplinary research, providing answers to real-life biological problems from a chemistry perspective.
Дополнительное описание: Introduction.- Biological Active Antifungal Peptides.- Protein Ligands Engineering.- Coiled Coil Binding Induced Covalent Cross-linking.- Cell Surface Receptor Labeling.- Summary and Conclusion.

Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging and Nanoparticle Surface Modification, Wang