Redox State as a Central Regulator of Plant-Cell Stress Responses, Gupta

Автор: Ralph A. Bradshaw
Название: Regulation of Organelle and Cell Compartment Signaling,
ISBN: 0123822130 ISBN-13(EAN): 9780123822130
Издательство: Elsevier Science
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Цена: 9767.00 р.
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Описание: Suitable for researchers across molecular biology, biochemistry, cell biology and genetics, this title includes articles that emphasize signaling to and from intracellular compartments including transcriptional responses to cytoplasmic and nuclear signaling events, chromatin remodeling and stress responses, and more.

Автор: Kaldis Philipp
Название: Cell Cycle Regulation
ISBN: 3540345523 ISBN-13(EAN): 9783540345527
Издательство: Springer
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Цена: 44582.00 р.
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Описание: The cell cycle is tightly regulated on many different levels to ensure properly controlled proliferation. Deregulation of cell cycle regulation is a hallmark of cancer. In this book, many aspects of cell cycle regulation are discussed, which include G1, S, M phase control, ubiquitin-mediated degradation, DNA damage response, mitotic spindle checkpoint, the centrosome cycle, Retinoblastoma protein family, the Myc oncogene, and mouse models for tumor suppressors, cyclin-dependent kinases, and meiosis. These chapters written by experts provide an updated view on how the cell cycle is regulated in vivo and about the involvement of cell cycle regulators in cancer.

Автор: Batini?-Haberle
Название: Redox-Active Therapeutics
ISBN: 3319307037 ISBN-13(EAN): 9783319307039
Издательство: Springer
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Цена: 30745.00 р.
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Описание: This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. Subsequent sections and chapters describe more specialized aspects of central nervous system injuries, neurodegenerative diseases, pain, radiation injury and radioprotection (such as of brain, lungs, head and neck and erectile function) and neglected diseases (e.g., leishmaniasis). It encompasses several major classes of redox-active experimental therapeutics, which include porphyrins, salens, nitrones, and most notably metal-containing (e.g., Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations with nanomaterials and quantum dots. Numerous illustrations, tables and figures enhance and complement the text; extensive references to relevant literature are also included. Redox-Active Therapeutics is an invaluable addition to Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice series. It is essential reading for researchers, clinicians and graduate students interested in understanding and exploring the Redoxome—the organism redox network—as an emerging frontier in drug design, redox biology and medicine.

Автор: Jakob
Название: Oxidative Stress and Redox Regulation
ISBN: 9400757867 ISBN-13(EAN): 9789400757868
Издательство: Springer
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Цена: 25155.00 р.
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Описание: In this book examines how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.