Fern?ndez Physics at the Biomolecular Interface 9783319308517

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Автор: Fern?ndez
Название: Physics at the Biomolecular Interface
ISBN: 9783319308517
Издательство: Springer
Классификация:

Прикладная физика и специальные темы

Биофизика

Физическая химия

Биохимия

Молекулярная биология

Промышленная химия

Технологии производства фармацевтических препаратов

ISBN-10: 3319308513
Обложка/Формат: Hardback
Страницы: 483
Вес: 0.91 кг.
Дата издания: 2016
Серия: Soft and Biological Matter
Язык: English
Иллюстрации: 87 black & white illustrations, 208 colour illustrations, 17 black & white tables, 200 colour tables, biography
Размер: 234 x 156 x 27
Читательская аудитория: General (us: trade)
Основная тема: Physics
Подзаголовок: Fundamentals for Molecular Targeted Therapy
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This bookfocuses primarily on the role of interfacial forces in understanding biologicalphenomena at the molecular scale. By providing a suitable statisticalmechanical apparatus to handle the biomolecular interface, the book becomesuniquely positioned to address core problems in molecular biophysics. Ithighlights the importance of interfacial tension in delineating a solution tothe protein folding problem, in unravelling the physico-chemical basis ofenzyme catalysis and protein associations, and in rationally designingmolecular targeted therapies. Thus grounded in fundamental science, the bookdevelops a powerful technological platform for drug discovery, while it is setto inspire scientists at any level in their careers determined to address themajor challenges in molecular biophysics.Theacknowledgment of how exquisitely the structure and dynamics of proteins and theiraqueous environment are related attests to the overdue recognition thatbiomolecular phenomena cannot be effectively understood without dealing withinterfacial behaviour. There is an urge to grasp how biologically relevantbehaviour is shaped by the structuring of biomolecular interfaces and howinterfacial tension affects the molecular events that take place in the cell.This book squarely addresses these needs from a physicist perspective.Thebook may serve as a monograph for practitioners and, alternatively, as anadvanced textbook. Fruitful reading requires a background in physical chemistryand some basics in biophysics. The selected problems at the end of the chaptersand the progression in conceptual difficulty make it a suitable textbook for agraduate level course or an elective course for seniors majoring in chemistry,physics, biomedical engineering or related disciplines.
Дополнительное описание: Chapter 1 Interfacial Physics forWater in Biology.- Chapter 2 DielectricStructure of Aqueous Interfaces: From Classical non-Debye Electrostatics to aQuantum Theory of Interfacial Tension.- Chapter 3 Solution to the Protein FoldingProblem.- Chapter 4 Epis

Physics at the Biomolecular Interface, Fern?ndez