Redox Proteomics - From Protein Modifications to Cellular Dysfunction and Diseases, Dalle-Donne

Автор: Cecilio J. Vidal
Название: Post-Translational Modifications in Health and Disease
ISBN: 1461427002 ISBN-13(EAN): 9781461427001
Издательство: Springer
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Цена: 41787.00 р.
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Описание: Post-translational modifications serve many different purposes in a wide variety of cellular processes. This book provides the reader with nineteen reviews that stimulate further investigations in the proteomic field.

Автор: Hubert Rehm
Название: Protein Biochemistry and Proteomics,
ISBN: 012088545X ISBN-13(EAN): 9780120885459
Издательство: Elsevier Science
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Цена: 8251.00 р.
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Описание: Connects concepts and creates links to criminal behavior across crimes murder, sexual assault, and arson. This work provides a theoretical and practical foundation for understanding the motivation and dynamics in a range of serial offenses. It includes case examples that offer real-world uses of behavioral profiling in investigations.

Автор: Reeve
Название: Mitochondrial Dysfunction in Neurodegenerative Disorders
ISBN: 3319286358 ISBN-13(EAN): 9783319286358
Издательство: Springer
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Цена: 18866.00 р.
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Описание: This second edition brings together up-to-date contributionsfrom leaders in the field internationally on the various ways in whichmitochondrial dysfunction contributes to the pathogenesis of neurodegenerativediseases, including Parkinson’s disease, Alzheimer’s disease and multiplesclerosis. The reader is guided through the basic functions of mitochondria andthe mechanisms that lead to their dysfunction, and on to the consequences ofthis dysfunction for neuronal function before finishing with the modelling ofthese disorders and discussion of new potential therapeutic targets. Additional chapters have been added to the book to reflectadvances in the field and there are many new contributors and topics, includinghow mitochondria are degraded and the interaction of the mitochondria withpathologically relevant proteins. Mitochondrial Dysfunction in Neurodegenerative Disordersprovides an accessible, authoritative guide to this important area forneurologists; research and clinical neuroscientists; neuropathologists; andresidents with an interest in clinical research.

Автор: Sechi Salvatore
Название: Quantitative Proteomics by Mass Spectrometry
ISBN: 1588295710 ISBN-13(EAN): 9781588295712
Издательство: Springer
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Цена: 21661.00 р.
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Описание: This volume is a compendium of cutting-edge protocols for quantitative proteomics, and presents the most significant methods used in the field today. Attention is given to state-of-the-art techniques for the characterization of the phosphoproteome and tandem MS for detection of inborn errors of metabolism.

Автор: Gary B. Smejkal and Alexander Lazarev
Название: Separation Methods In Proteomics
ISBN: 0824726995 ISBN-13(EAN): 9780824726997
Издательство: Taylor&Francis
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Цена: 33686.00 р.
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Описание: Driven by the widespread growth of proteomic practices, protein separation techniques have been refined to minimize variability, optimize particular applications, and adapt to user preferences in the analysis of proteins. "Separation Methods in Proteomics" provides a comprehensive examination of all major separation techniques for proteomics research. Written as a compilation of hands-on methods exemplified by the work of several recognized leaders in the field, this book may serve as a guide for selection of the optimal separation strategies to solve particular biological problems.

Recent progress in the development of robust analytical techniques and instrumentation has created the need for good quality biological samples that are subject to analysis.Emphasizing the importance of sample preparation, the book explains how proteomes can be divided into smaller, less complicated 'subproteomes' for individual analysis. It also highlights several hybrid approaches that take into account protein interactions. Including applications of the separation methods currently employed in proteomic analyses for both clinical and basic research, "Separation Methods in Proteomics" contains practical information that can enhance the current and future endeavors of scientists in proteomics, genomics, transcriptomics, biomarker discovery, and drug discovery.