Описание: This volume serves as a proteomics reference manual, describing experimental design and execution. The book also shows a large number of examples as to what can be achieved using proteomics techniques. As a relatively young area of scientific research, the breadth and depth of the current state of the art in proteomics might not be obvious to all potential users. There are various books and review articles that cover certain aspects of proteomics but they often lack technical details. Subject specific literature also lacks the broad overviews that are needed to design an experiment in which all steps are compatible and coherent. The objective of this book was to create a proteomics manual to provide scientists who are not experts in the field with an overview of:1. The types of samples can be analyzed by mass spectrometry for proteomics analysis.2. Ways to convert biological or ecological samples to analytes ready for mass spectral analysis.3. Ways to reduce the complexity of the proteome to achieve better coverage of the constituent proteins.4. How various mass spectrometers work and different ways they can be used for proteomics analysis5. The various platforms that are available for proteomics data analysis6. The various applications of proteomics technologies in biological and medical sciencesThis book should appeal to anyone with an interest in proteomics technologies, proteomics related bioinformatics and proteomics data generation and interpretation. With the broad setup and chapters written by experts in the field, there is information that is valuable for students as well as for researchers who are looking for a hands on introduction into the strengths, weaknesses and opportunities of proteomics.
Автор: Marcus Название: Quantitative Methods in Proteomics ISBN: 1617798843 ISBN-13(EAN): 9781617798849 Издательство: Springer Рейтинг: Цена: 13557 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology(TM) book surveys the principles of modern protein analysis, from statistical issues when planning proteomics experiments, to gel-based and mass spectrometry-based applications. Covers existing methods, software and data analysis.
Описание: It has been predicted that nearly half of all human proteins are glycosylated indicating the significance of glycoproteins in human health and disease. For example, the glycans attached to proteins have emerged as important biomarkers in the diagnosis of diseases such as cancers and play a significant role in how pathogenic viruses gain entry into human cells. The study of glycoproteins has now become a truly proteomic science. In the last few years, technology developments including in silico methods, high throughput separation and detection techniques have accelerated the characterization of glycoproteins in cells and tissues. Glyco-engineering coupled to rapid recombinant protein production has facilitated the determination of glycoprotein structures key to exploring and exploiting their functional roles. Each chapter in this volume is written by experts in the field and together provide a review of the state of the art in the emerging field of glycoproteomics.
Описание: *Contemporary, Broad Coverage covers every aspect of the rapidly changing field of proteomics from *Coherent and Student friendly based on the highly successful course developed by the author at Manchester University.
Автор: Twyman Название: Principles of Proteomics ISBN: 0815344724 ISBN-13(EAN): 9780815344728 Издательство: Taylor&Francis Рейтинг: Цена: 6478 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Principles of Proteomics, Second Edition, provides a concise and user-friendly introduction to the diverse technologies used for the large-scale analysis of proteins, as well as their applications, and their impact in areas such as drug discovery, agriculture, and the fight against disease. Proteomics is a fast-advancing field in which researchers seek to capture all the proteins in the cell and characterize them in ever more detail. Principles of Proteomics has been fully updated to reflect the most recent developments in the field without losing its focus on the underlying principles. With worked examples, case studies profiling both established and emerging technologies, and further reading lists for each chapter, Principles of Proteomics is an ideal introduction for students, researchers and those working in the industry.
Описание: Since the publication of the pioneering first edition of Chemical Genomics and Proteomics more than seven years ago, the area of chemical genomics has rapidly expanded and diversified to numerous novel methods and subdisciplines, such as chemical glycomics and lipidomics. This second edition has been updated to uniquely reflect this interdisciplinary feature as well as the remarkable developments that have occurred. The new edition also covers innovative applications from cell biology to drug discovery to, more recently, clinical diagnostics and medical practice, which utilize the concepts of chemical genomics.The text provides an overview of the strategies and methodologies of chemical genomics, focusing on emerging technologies and recent applications in the areas of combination chemical genetics, toxicogenomics, drug chemical genomics and proteomics, and orthogonal chemical genetics. It describes the development and application of novel analytical methods used in lipodomics, such as steroidomics. The book also discusses biomarker discovery applications of microarray technologies using DNA, RNA, and protein and glycan arrays. Chapters cover further applications of biomolecular biomarkers for disease diagnosis, in small molecule drug R&D, and during therapeutic use of medicines. These include prognostic, disease specific, response (surrogate), and toxicity biomarkers.In addition, the text explores the principles of contemporary systems biology and genomics in experimental medicine—a new paradigm that demonstrates a network-oriented view and advanced statistical and informatics data management, opening the way toward personalized medicine. Finally, various in silico chemogenomics approaches are addressed for predicting binding of drug candidates to undesirable targets, which would help in designing better clinical candidates with fewer side effects. This new edition benefits a broad range of readers from industrial and academic researchers in drug discovery, medicinal chemistry, and molecular and cell biology to physicians in clinical diagnostics and students in related fields of study.
Автор: Toldr? Название: Proteomics in Foods ISBN: 1461456258 ISBN-13(EAN): 9781461456254 Издательство: Springer Рейтинг: Цена: 15728 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book covers the principles of proteomics and details applications to foods, such as quality issues related with post-mortem processes in animal foods, identification of proteins, and safety issues like food authenticity and detection of animal species.
Автор: Whitfield, Philip D. Eckersall, David Название: Methods in animal proteomics ISBN: 0813817919 ISBN-13(EAN): 9780813817910 Издательство: Wiley Рейтинг: Цена: 19124 р. Наличие на складе: Поставка под заказ.
Описание: The study of proteomics provides researchers with a better understanding of disease and physiological processes in animals. Methods in Animal Proteomics will provide animal scientists and veterinarians currently researching these topics in domestic animals a firm foundation in the basics of proteomics methodology, while also reviewing important advances that will be of interest to established researchers in the field. Chapters will provide practical information on a range of topics including protein identification and separation, bioinformatics, and applications to disease and reproduction research. This text will be written by leading international proteomics experts and essential for researchers in the fields of animal biology and veterinary medicine.
Автор: Mishra, Nawin C Название: Introduction to proteomics ISBN: 0471754021 ISBN-13(EAN): 9780471754022 Издательство: Wiley Рейтинг: Цена: 9562 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proteomics provides an introductory insight on proteomics, discussing the basic principles of the field, how to apply specific technologies and instrumentation, and example applications in human health and diseases.
Автор: Igor Stagljar (Ed.) Название: Yeast Functional Genomics and Proteomics ISBN: 1934115711 ISBN-13(EAN): 9781934115718 Издательство: Springer Рейтинг: Цена: 13557 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Given the popularity and utility of Saccharomyces cerevisiae, yeast-based functional genomics and proteomics technologies have contributed greatly to our understanding of bacterial, yeast, fly, worm and human gene functions. This volume examines methods from the most major and fundamental techniques to more advanced concepts.
Автор: Rune Matthiesen (Ed.) Название: Clinical Proteomics ISBN: 1603271937 ISBN-13(EAN): 9781603271936 Издательство: Springer Рейтинг: Цена: 13557 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Discusses developments in clinical proteomics and describes in detail the algorithms used in publicly available software tools. This book aims to describe the background of the biology and experimental methods. It also reviews the pro and cons of the various experimental methods in relation to data analysis.
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