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Mass Spectrometry-Based Chemical Proteomics, Tao


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Цена: 23118.00р.
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Автор: Tao
Название:  Mass Spectrometry-Based Chemical Proteomics
ISBN: 9781118969557
Издательство: Wiley
Классификация:
ISBN-10: 1118969553
Обложка/Формат: Hardback
Страницы: 448
Вес: 0.83 кг.
Дата издания: 13.09.2019
Серия: Chemistry
Язык: English
Размер: 228 x 157 x 25
Читательская аудитория: Professional & vocational
Ключевые слова: Chemistry,Biology, life sciences
Основная тема: Mass Spectrometry
Ссылка на Издательство: Link
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Поставляется из: Англии
Описание:

PROVIDES STRATEGIES AND CONCEPTS FOR UNDERSTANDING CHEMICAL PROTEOMICS, AND ANALYZING PROTEIN FUNCTIONS, MODIFICATIONS, AND INTERACTIONS--EMPHASIZING MASS SPECTROMETRY THROUGHOUT

Covering mass spectrometry for chemical proteomics, this book helps readers understand analytical strategies behind protein functions, their modifications and interactions, and applications in drug discovery. It provides a basic overview and presents concepts in chemical proteomics through three angles: Strategies, Technical Advances, and Applications. Chapters cover those many technical advances and applications in drug discovery, from target identification to validation and potential treatments.

The first section of Mass Spectrometry-Based Chemical Proteomics starts by reviewing basic methods and recent advances in mass spectrometry for proteomics, including shotgun proteomics, quantitative proteomics, and data analyses. The next section covers a variety of techniques and strategies coupling chemical probes to MS-based proteomics to provide functional insights into the proteome. In the last section, it focuses on using chemical strategies to study protein post-translational modifications and high-order structures.

  • Summarizes chemical proteomics, up-to-date concepts, analysis, and target validation
  • Covers fundamentals and strategies, including the profiling of enzyme activities and protein-drug interactions
  • Explains technical advances in the field and describes on shotgun proteomics, quantitative proteomics, and corresponding methods of software and database usage for proteomics
  • Includes a wide variety of applications in drug discovery, from kinase inhibitors and intracellular drug targets to the chemoproteomics analysis of natural products
  • Addresses an important tool in small molecule drug discovery, appealing to both academia and the pharmaceutical industry

Mass Spectrometry-Based Chemical Proteomics is an excellent source of information for readers in both academia and industry in a variety of fields, including pharmaceutical sciences, drug discovery, molecular biology, bioinformatics, and analytical sciences.




Mass Spectrometry

Автор: Gross
Название: Mass Spectrometry
ISBN: 3642107095 ISBN-13(EAN): 9783642107092
Издательство: Springer
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Цена: 12571.00 р.
Наличие на складе: Поставка под заказ.

Описание: This highly successful textbook, acclaimed for its comprehensiveness,  accuracy, and its many excellent illustrations and photographs now comes in its second edition. Completely revised and substantially extended it  offers:– New chapter on Tandem Mass Spectrometry covering instrumentation, methods for ion activation (CID, ECD, ETD, IRMPD), and applications– New chapter on Ambient Mass Spectrometry (DART, DESI, and more)– New chapter on Inorganic Mass Spectrometry including element speciation and imaging– Learning Objectives for all chapters– Advanced Instrumentation such as orbitraps, linear ion traps, tandem TOFs, FT-ICR and the highly variable hybrid instruments– Updated Problems and Solutions website (www.ms-textbook.com) J?rgen H. Gross provides in-depth explanations of concepts, methods, and techniques. Students and professionals alike are guided step-by-step from the basics to the successful application of mass spectrometry. Starting from the very principles of gas-phase ion chemistry, isotopic composition, and accurate mass, J?rgen H. Gross leads through the design of all types of mass analyzers and ionization methods to mass spectral interpretation and coupling techniques. His book offers a balanced mixture of practice-oriented information and theoretical background supported by a wealth of references.From reviews of the previous edition:“…one of the best textbooks on mass spectrometry I have seen so far.” International Journal of Mass Spectrometry“…can be recommended unreservedly as a textbook and reference source…” Angewandte Chemie, International Edition

The Determination of Chemical Elements in Food - Applications for Atomic and Mass Spectrometry

Автор: Caroli
Название: The Determination of Chemical Elements in Food - Applications for Atomic and Mass Spectrometry
ISBN: 0471687847 ISBN-13(EAN): 9780471687849
Издательство: Wiley
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Цена: 30880.00 р.
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Описание: State-of-the-art tools and applicationsfor food safety and food science research Atomic spectroscopy and mass spectrometry are important tools for identifying and quantifying trace elements in food products-elements that may be potentially beneficial or potentially toxic.

Mass Spectrometry Data Analysis in Proteomics

Автор: Matthiesen Rune
Название: Mass Spectrometry Data Analysis in Proteomics
ISBN: 158829563X ISBN-13(EAN): 9781588295637
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Aims to support researchers in deciding which programs to use in various tasks related to analysis of mass spectrometry data in proteomics. This work covers chapters that give a description of the theoretical background of each topic followed by descriptions of programs and the parameters best suited for different cases.

Quantitative Proteomics by Mass Spectrometry

Автор: Sechi Salvatore
Название: Quantitative Proteomics by Mass Spectrometry
ISBN: 1588295710 ISBN-13(EAN): 9781588295712
Издательство: Springer
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Цена: 21661.00 р.
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Описание: This volume is a compendium of cutting-edge protocols for quantitative proteomics, and presents the most significant methods used in the field today. Attention is given to state-of-the-art techniques for the characterization of the phosphoproteome and tandem MS for detection of inborn errors of metabolism.

Statistical Analysis of Proteomics, Metabolomics, and Lipidomics Data Using Mass Spectrometry

Автор: Datta
Название: Statistical Analysis of Proteomics, Metabolomics, and Lipidomics Data Using Mass Spectrometry
ISBN: 3319458078 ISBN-13(EAN): 9783319458076
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This book presents an overview of computational and statistical design and analysis of mass spectrometry-based proteomics, metabolomics, and lipidomics data. This contributed volume provides an introduction to the special aspects of statistical design and analysis with mass spectrometry data for the new omic sciences. The text discusses common aspects of design and analysis between and across all (or most) forms of mass spectrometry, while also providing special examples of application with the most common forms of mass spectrometry. Also covered are applications of computational mass spectrometry not only in clinical study but also in the interpretation of omics data in plant biology studies.Omics research fields are expected to revolutionize biomolecular research by the ability to simultaneously profile many compounds within either patient blood, urine, tissue, or other biological samples. Mass spectrometry is one of the key analytical techniques used in these new omic sciences. Liquid chromatography mass spectrometry, time-of-flight data, and Fourier transform mass spectrometry are but a selection of the measurement platforms available to the modern analyst. Thus in practical proteomics or metabolomics, researchers will not only be confronted with new high dimensional data types—as opposed to the familiar data structures in more classical genomics—but also with great variation between distinct types of mass spectral measurements derived from different platforms, which may complicate analyses, comparison, and interpretation of results.


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