Описание: Serving as the only systematic and comprehensive treatment on the topic of nanoparticle-based materials, this book covers synthesis, characterization, assembly, shaping and sintering of all types of nanoparticles including metals, ceramics, and semiconductors. A single-authored work, it is suitable as a graduate-level text in nanomaterials courses.
Автор: Bagnoli Fabio, Rappuoli Rino Название: Advanced Vaccine Research: Methods for the Decade of Vaccines ISBN: 1910190039 ISBN-13(EAN): 9781910190036 Издательство: Неизвестно Рейтинг: Цена: 45980.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Skwarczynski, Mariusz Название: Micro and Nanotechnology in Vaccine Development ISBN: 0323399819 ISBN-13(EAN): 9780323399814 Издательство: Elsevier Science Рейтинг: Цена: 21054.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress.
MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles.
Автор: Camilla Foged; Thomas Rades; Yvonne Perrie; Sarah Название: Subunit Vaccine Delivery ISBN: 1493948512 ISBN-13(EAN): 9781493948512 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
.- 1 Immunological Background
.- 2 Classification of Vaccines
.- 3 Aluminum Adjuvants - Basic Concepts and Progress in Understanding
.- 4 Emulsions as Vaccine Adjuvants
.- 5 The application of liposomes as vaccine adjuvants
.- 6 Developing Bilayer-based Delivery Systems for Oral Delivery of Subunit Vaccines
.- 7 Cubosomes - Structure, Preparation and Use as an Antigen Delivery System
.- 8 ISCOMs as a Vaccine Delivery System
.- 9 Virus-like Particles, a Versatile Subunit Vaccine Platform
.- 10 Polymeric Particulates for Subunit Vaccine Delivery
.- 11 Gels as Vaccine Delivery Systems
.- 12 Implants as Sustained Release Delivery Devices for Vaccine Antigens
.- 13 Dendritic Cell-based Vaccines
.- 14 Parenteral Vaccine Administration - Tried and True
.- 15 Nasal Administration of Vaccines
.- 16 Pulmonary Administration of Subunit Vaccines
.- 17 Vaginal Delivery of Subunit Vaccines
.- 18 Transcutaneous Administration
.- 19 Pharmaceutical Analysis and Quality Control of Vaccines
.- 20 The Physical Analysis of Vaccines
.- 21 Characterizing the Association between Antigens and Adjuvants.
Автор: Camilla Foged; Thomas Rades; Yvonne Perrie; Sarah Название: Subunit Vaccine Delivery ISBN: 1493914162 ISBN-13(EAN): 9781493914166 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume compiles the concepts essential for the understanding of the pharmaceutical science and technology associated with the delivery of subunit vaccines. Twenty-one chapters are divided into four main parts: (I) Background; (2) Delivery Systems for Subunit Vaccines; (3) Delivery Routes, Devices and Dosage Forms; and (4) Pharmaceutical Analysis and Quality Control of Vaccines. Part one provide a basic background with respect to immunology and general vaccine classification. In part two, it presents representative types of vaccine delivery systems individually with focus on the physicochemical properties of the systems and their significance for the immune response they stimulate. These delivery systems include aluminum adjuvants, emulsions, liposomes, bilosomes, cubosomes/hexosomes, ISCOMs, virus-like particles, polymeric nano- and microparticles, gels, implants and cell-based delivery systems. Following these chapters, part three addresses the challenges associated with vaccine delivery via specific routes of administration—in particular subcutaneous, intramuscular, oral, nasal, pulmonary, transdermal and vaginal administration. Furthermore, the specific administration routes are discussed in combination with device technologies relevant for the respective routes as well as dosage forms appropriate for the device technology. Finally, the fourth part concerns pharmaceutical analysis and quality control of subunit vaccines.
Автор: Igor S Lukashevich; Haval Shirwan Название: Novel Technologies for Vaccine Development ISBN: 3709118174 ISBN-13(EAN): 9783709118177 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.
Автор: Gregory Gregoriadis; Brenda McCormack; Anthony C. Название: Vaccine Design ISBN: 0306458187 ISBN-13(EAN): 9780306458187 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a NATO ASI held in Cape Sounion, Greece, June 24-July 5, 1996
Автор: Sunil Thomas Название: Vaccine Design ISBN: 1493980386 ISBN-13(EAN): 9781493980383 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This text provides a practical guide providing step-by-step protocol to design and develop vaccines. Chapters detail protocols for developing novel vaccines against infectious bacteria, viruses, fungi, and parasites for humans and animals. Volume 1: Vaccines for Human Diseases has an introductory section on how vaccines impacted diseases, the immunological mechanism of vaccines, future challenges for vaccinologists, and current trends in vaccinology. The design of human vaccines for viral, bacterial, fungal, parasitic and prion diseases as well as vaccines for drug abuse, allergy, and tumor vaccines are also described in this volume. As a volume in the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Vaccine Design: Methods and Protocols, Volume 1: Vaccines for Human Diseases aims to ensure successful results in the further study of this vital field.
Автор: Igor S Lukashevich; Haval Shirwan Название: Novel Technologies for Vaccine Development ISBN: 3709119804 ISBN-13(EAN): 9783709119808 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines.
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