Statistical genomics, 

Автор: Trevor Hastie; Robert Tibshirani; Jerome Friedman
Название: The Elements of Statistical Learning
ISBN: 0387848576 ISBN-13(EAN): 9780387848570
Издательство: Springer
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Цена: 10480.00 р.
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Описание: This major new edition features many topics not covered in the original, including graphical models, random forests, and ensemble methods. As before, it covers the conceptual framework for statistical data in our rapidly expanding computerized world.

Автор: Cornel Mulhardt
Название: Molecular Biology and Genomics,
ISBN: 0120885468 ISBN-13(EAN): 9780120885466
Издательство: Elsevier Science
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Цена: 6772.00 р.
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Описание: Never before has it been so critical for lab workers to possess the proper tools and methodologies necessary to determine the structure, function, and expression of the corresponding proteins encoded in the genome. Mulhardt's Molecular Biology and Genomics helps aid in this daunting task by providing the reader with tips and tricks for more successful lab experiments. This strategic lab guide explores the current methodological variety of molecular biology and genomics in a simple manner, addressing the assets and drawbacks as well as critical points. It also provides short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods.

Автор: Hartl, D.L.
Название: Essential Genetics: a Genomics Perspective
ISBN: 1449686885 ISBN-13(EAN): 9781449686888
Издательство: Jones & Bartlett
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Цена: 11614.00 р.
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Описание: Every new copy includes access to the student companion website

Updated throughout to reflect the latest discoveries in this fast-paced field, Essential Genetics: A Genomics Perspective, Sixth Edition, provides an accessible, student-friendly introduction to modern genetics. Designed for the shorter, less comprehensive course, the Sixth Edition presents carefully chosen topics that provide a solid foundation to the basic understanding of gene mutation, expression, and regulation. It goes on to discuss the development and progression of genetics as a field of study within a societal and historical context. The Sixth Edition includes new learning objectives within each chapter which helps students identify what they should know as a result of their studying and highlights the skills they should acquire through various practice problems.

What's new in the Sixth Edition?

Chapter 1 includes a new section on the origin of life
Chapter 2 includes a revised discussion of the complementation test and how it is used to determine whether two mutations have defects in the same gene
Chapter 3 incorporates new data showing that the folding of interphase chromatin into chromosome territories has the form of a fractal globule. It also includes a new section on progenitor cells and embryonic stem cells
Chapter 4 includes a new section discussing how copy-number variation in human amylase evolved in response to increased dietary starch as well as the latest on hotspots of recombination
Chapter 5 is updated with the latest information on hazards of polycarbonate food containers. It also includes a new section on the genetics of schizophrenia and autism spectrum disorder
Chapter 6 includes a revised section on restriction mapping and also discusses the newest massively parallel DNA sequencing technologies that can yield the equivalent of 200 human genomes' worth of DNA sequence in a single sequencing run
Chapter 7 has been updated with a shortened and streamlined discussion of recombination in bacteriophage
Chapter 8 includes new discoveries concerning the mechanisms of intrinsic transcriptional termination as well as rho-dependent termination
Chapter 9 is updated with a new section on stochastic effects on gene expression and an expanded discussion of the lactose operon. There is also a revised discussion of galactose gene regulation in yeast, as well as new sections on lon noncoding RNAs
Chapter 10 includes new sections on ancient DNA sequences of the Neandertal and Denisovan genomes
Chapter 11 examines master control genes in development
Chapter 12 includes a new section on the repair of double-stranded breaks in DNA by nonhomologous end joining or template-directed gap repair
Chapter 13 has been extensively revised with the latest data on cancer.
Chapter 14 includes a new section on the detection of natural selection, as well as a new section on conservation genetics

Key Features of Essential Genetics, Sixth Edition:

New Learning Objectives within each chapter help students to:
Identify what they should know or be able to do as a result of their study
Focus on the knowledge they should have acquired from studying the chapter
Guide them to identify key concepts and use them at a variety of learning levels including comprehension, application, analysis, and synthesis
Highlight the skill they should acquire through practice of various problem types

Each chapter includes several different types and levels of problems, including: concept, synthesis, and discussion questions, problem solving questions, and application and analysis problems.
The companion Website, GeNETics on the Web, includes numerous study tools and learning resources such as animated flashcards, crosswords, and practice quizzes
An electronic Student Study Guide and Solutions Manual is available, containing chapter summaries, key terms, and extra study questions, as well as worked

Автор: Shizhong Xu
Название: Principles of Statistical Genomics
ISBN: 1489994041 ISBN-13(EAN): 9781489994042
Издательство: Springer
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Цена: 11753.00 р.
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Описание: This book synthesizes current statistical methodologies applied to genome study, exploring statistical models and methods behind major bioinformatics software. Helps researchers choose the optimal algorithm to analyze data and to better interpret results.

Автор: Pierce Benjamin A
Название: Genetics Essentials. Concepts and Connections. - 3th ed.
ISBN: 1464190755 ISBN-13(EAN): 9781464190759
Издательство: Springer
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Цена: 9083.00 р.
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Описание: Derived from Ben Pierce's popular and acclaimed Genetics: A Conceptual Approach, this streamlined text covers basic transmission, molecular, and population genetics.