Описание: Through the use of practical examples and solutions, this timely Fifth Edition has been updated and expanded to provide the most complete and comprehensive guide to the various statistical applications and research issues in the pharmaceutical industry, particularly clinical trials and bioequivalence studies.
Описание: Offers a comprehensive overview of the medical applications of pharmaceutical particulate carriers, discussing the various routes of administration and controlled delivery of sites of action. Intravenous liposomal therapy for retroviral infections, especially AIDS, is discussed.
Описание: "The Encyclopaedia of Pharmaceutical Technology" presents authoritative and contemporary articles on all aspects of drug development, dosage forms,
manufacturing, and regulation - enabling the specialist and novice alike to keep abreast of developments in this rapidly evolving and highly competitive field. This is a dependable
reference tool and a solid investment for years to come - it maintains currency through its supplements [Volume 18/Supplement 1: Published November, 1998]. The Encyclopaedia
contains interdisciplinary contributions in a wide array of subjects, including: Drugs decomposition metabolism - pharmaceutical incompatibilities, pharmacokinetics physicochemical
properties, preformulation stability; Drug Delivery Systems and Devices - Development and Manufacture analysis and controls bioavailability use of computerization formulation and
processing alternatives national and international registration packaging patents process validation scale-up safety and efficacy stability standards; Post-Production and Practical
Consideratio
s governmental/industrial/professional organizations legal aspects national and international agencies patent life of drugs patient compliancea and much more!
Описание: Vibrational spectroscopy is a critical technology within the pharmaceutical industry. This volume aims to present key themes, established and emerging, within different research as well as presenting detailed contributions on the instrumentation, methodology, data treatment, and applications associated within this area of research.
Название: Nanotechnology applications in coatings ISBN: 0841274487 ISBN-13(EAN): 9780841274488 Издательство: Oxford Academ Рейтинг: Цена: 14667 р. Наличие на складе: Поставка под заказ.
Описание: Nanotechnology based coating products have shown remarkable growth in recent years. This book begins with an overview chapter on recent scientific and technological advancements in nanotechnology applications in this field. Subsequent chapters cover, in detail, a number of key applications of nanotechnology in coatings, along with the related fundamental science. Some contributions focus on issues related to inorganic/organic nanocomposite coating films, including dispersion of inorganic nanoparticles and nanoclays. Surface Functionalized nanoparticles, predispersed inorganic nanoparticles that can be mixed with existing organic coating formulations and organic/inorganic hybrid latexes are approaches discussed for preparation of nanocomposite coatings having improved scratch, corrosion, and UV resistance. Several chapters address nanostructure development approaches to impart specialized functionality and performance to coatings. Nanoporous adhesive microbial ink-jet ink for miniature biosensors and biocatalysts and nanostructured conjugated polymer networks are discussed. Characterization of nanostructure and nanoparticle dispersion in coatings is a difficult challenge, and this challenge is addressed in several chapters. Assessment of phopocatalytic activity of nanoparticles, use of atomic force microscopy, applications of Nano-Indentation for mechanical property measurements, and nano-thermal analysis are discussed. Size determination techniques suitable for nanoparticles are also reviewed. The highly multidisciplinary nature of the field is evident throughout the book.
Автор: J Djuris Название: Computer-Aided Applications in Pharmaceutical Technology, ISBN: 1907568271 ISBN-13(EAN): 9781907568275 Издательство: Elsevier Science Рейтинг: Цена: 17243 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and investigation of pharmaceutical products and processes enables application of quality by design concept that is being promoted by the regulatory authorities worldwide. Computer-aided applications in pharmaceutical technology covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with emphasis of their application in process control, neural computing (artificial neural networks, fuzzy logic and decision trees, evolutionary computing and genetic algorithms, self-organizing maps), computer-aided biopharmaceutical characterization as well as application of computational fluid dynamics in pharmaceutical technology. All of these techniques are essential tools for successful building of quality into pharmaceutical products and processes from the early stage of their development to selection of the optimal ones. In addition to theoretical aspects of various methods, the book provides numerous examples of their application in the field of pharmaceutical technology.
Описание: Absorption, distribution, metabolism, excretion, and toxicity (ADMET) are among the most critical factors that affect pharmacological response and drug safety. Preclinical and clinical tools and proof–of–concept investigations can improve drug design and make clinical investigations of drug candidate progress more effective. The correlation between in vitro, in vivo, and in silico ADMET data can further translate the pharmacokinetics and response of drugs across species and humans and bring forth new approaches towards better drug therapy by revealing hidden adverse side effects, adverse reactions, drug–drug interactions, and mechanisms of drug disposition. To address this critical aspect of drug development, Translational ADMET for Drug Therapy presents effective technologies, methods, applications, data interpretation, and decision–making tactics for pharmaceutical and preclinical scientists. Chapters cover case studies and in vivo, in vitro, and in silico tools for optimal drug design, with new translational approaches to drug development and investigation. Compiling the most effective approaches and technologies used to investigate ADMET and PKPD, this book offers a number of key benefits that include: Illustration of ADME properties from bedside to bench and bench to bedside, for the design of safe and effective medicine in human populations Examples that demonstrate the integration of in vitro, in vivo, and in silico data to address human PKPD and TKTD and help determine the proper therapeutic dosage Discussion of successful tools for evaluating drugs and covers current translational ADMET with regulatory guidelines A hands–on manual for researchers and scientists to design and execute in vitro, in silico, preclinical, and clinical studies
Описание: The Handbook of Membrane Separations: Chemical, Pharmaceutical, Food, and Biotechnological Applications, Second Edition provides detailed information on membrane separation technologies from an international team of experts.
The handbook fills an important gap in the current literature by providing a comprehensive discussion of membrane applications in the chemical, food, pharmaceutical, and biotechnology industries as well as in the treatment of toxic industrial effluents.
This revised second edition has been updated and expanded with discussions of new membrane products and processes and novel applications in engineering, life sciences, and energy conversion.
It also includes new chapters in the field of membrane science and technology covering recent advances in RO and UF, ionic liquids, nanotechnology, roles of membrane in power generation, updates on fuel cells, new membrane extraction configuration, and other important topics.
The handbook is equally suited for the newcomer to the field as it is for process engineers and research scientists (membranologists/membrane experts) who are interested in obtaining more advanced information about specific applications. It provides readers with a comprehensive and well-balanced overview of the present state of membrane science and technology.
Автор: Jean Cornier (Editor), Название: Pharmaceutical Nanotechnology - Innovation and Production ISBN: 3527340548 ISBN-13(EAN): 9783527340545 Издательство: Wiley Рейтинг: Цена: 27143 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With its focus on concrete methods and recent advances in applying nanotechnology to develop new drug therapies and medical diagnostics, this book provides an overall picture of the field, from the fundamentals of nanopharmacy with the characterisation and manufacturing methods to the role of nanoparticles and substances.
Описание: Covering various functions and phases of pharmaceutical research and development, this work explains how applications are used at different stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. It also includes sections on computers in pharmaceutical research and development.
Автор: Douroumis Название: Hot-Melt Extrusion: Pharmaceutical Applications ISBN: 0470711183 ISBN-13(EAN): 9780470711187 Издательство: Wiley Рейтинг: Цена: 14409 р. Наличие на складе: Поставка под заказ.
Описание: Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets.
Описание: Written by international experts from within the sector, this is the first book to focus on industrial pharmaceutical research. As such, it responds to the combination of such pharmaceutical interests as drug delivery, drug targeting, quality and safety m
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