Описание: The study of vaccine adjuvants has developed into an exciting area of work. In this authoritative and versatile book, expert researchers in the field provide clear and concise guidance on how to go about assessing the activity of adjuvant products.
Автор: J C Tong Название: Computer-Aided Vaccine Design, ISBN: 1907568417 ISBN-13(EAN): 9781907568411 Издательство: Elsevier Science Рейтинг: Цена: 20212.00 р. Наличие на складе: Поставка под заказ.
Описание: Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates.Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. Chapters include: MHC and T cell responses; Immunoglobulins and B cell responses; Scientific publications and databases; Database design; Computational T cell vaccine design; Computational B cell vaccine design; infectious disease informatics; Vaccine safety and quality assessments; and Vaccine adjuvant informatics.
Автор: Spriggs Название: Topics in Vaccine Adjuvant Research ISBN: 0849357195 ISBN-13(EAN): 9780849357190 Издательство: Taylor&Francis Рейтинг: Цена: 41342.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Topics in Vaccine Adjuvant Research provides a concise, focused review of the immunological basis of adjuvant activity
Автор: Koff Название: Vaccine Research and Development ISBN: 082478619X ISBN-13(EAN): 9780824786199 Издательство: Taylor&Francis Рейтинг: Цена: 36749.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Reviews advances in immunization research and addresses scientific and public policy challenges for moving candidate vaccines from the laboratory to the population. This title analyzes the capacity of lipophilic components to chemically modify peptide and protein antigens and augment their immunogenicity.
Автор: Bloom, Barry R. Название: The Vaccine Book ISBN: 0128021748 ISBN-13(EAN): 9780128021743 Издательство: Elsevier Science Рейтинг: Цена: 15831.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. . Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk.
Автор: Camilla Foged; Thomas Rades; Yvonne Perrie; Sarah Название: Subunit Vaccine Delivery ISBN: 1493914162 ISBN-13(EAN): 9781493914166 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume compiles the concepts essential for the understanding of the pharmaceutical science and technology associated with the delivery of subunit vaccines. Twenty-one chapters are divided into four main parts: (I) Background; (2) Delivery Systems for Subunit Vaccines; (3) Delivery Routes, Devices and Dosage Forms; and (4) Pharmaceutical Analysis and Quality Control of Vaccines. Part one provide a basic background with respect to immunology and general vaccine classification. In part two, it presents representative types of vaccine delivery systems individually with focus on the physicochemical properties of the systems and their significance for the immune response they stimulate. These delivery systems include aluminum adjuvants, emulsions, liposomes, bilosomes, cubosomes/hexosomes, ISCOMs, virus-like particles, polymeric nano- and microparticles, gels, implants and cell-based delivery systems. Following these chapters, part three addresses the challenges associated with vaccine delivery via specific routes of administration—in particular subcutaneous, intramuscular, oral, nasal, pulmonary, transdermal and vaginal administration. Furthermore, the specific administration routes are discussed in combination with device technologies relevant for the respective routes as well as dosage forms appropriate for the device technology. Finally, the fourth part concerns pharmaceutical analysis and quality control of subunit vaccines.
Автор: Igor S Lukashevich; Haval Shirwan Название: Novel Technologies for Vaccine Development ISBN: 3709118174 ISBN-13(EAN): 9783709118177 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.
Автор: Yehuda Shoenfeld,Nancy Agmon–Levin Название: Vaccines and Autoimmunity ISBN: 1118663438 ISBN-13(EAN): 9781118663431 Издательство: Wiley Рейтинг: Цена: 22485.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants specifically aluminum in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.
Автор: Brian K. Nunnally; Vincent E. Turula; Robert D. Si Название: Vaccine Analysis: Strategies, Principles, and Control ISBN: 3662450232 ISBN-13(EAN): 9783662450239 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses;
Автор: Boom Название: Understanding and Managing Vaccine Concerns ISBN: 3319075624 ISBN-13(EAN): 9783319075624 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Smallpox, measles, diphtheria, polio: vaccines have diminished their power, and in some cases, eradicated these dreaded diseases. Yet this century has seen growing numbers of parents refusing vaccinations for their children, not only endangering them but also increasing the risk of outbreaks and epidemics of vaccine-preventable diseases.
Understanding and Managing Vaccine Concerns concisely explainsthe evolution of vaccine concerns, and gives clinicians hands-on help in dealing with vaccine hesitation and outright refusal among parents. Persistent themes in refusal, such as a supposed autism/vaccine link and the belief that too many vaccines are given too soon, are discussed and recent statistics given for trends in vaccine refusal and delay. Central to the book is a detailed guide to vaccine concern management, with sample responses that readers can tailor to address vaccine refusal and specific concerns regarding individual vaccines and their components. This thorough grounding will assist providers in countering misinformation with facts and allaying fears with medically and ethically sound responses. Included in this practical resource:
A brief history of vaccine concerns.
Current trends in vaccine hesitancy and refusal.
Health implications of vaccine refusal.
Characteristics and beliefs of vaccine-concerned parents.
The CASE approach: a management strategy for vaccine concerns.
Additional considerations in management strategies.
The debate over vaccination isn't going away any time soon, and neither is the potential threat to public health, making Understanding and Managing Vaccine Concerns a timely and necessary addition to the libraries of pediatricians, nurses, and other healthcare providers.
Автор: Fox Название: Vaccine Adjuvants ISBN: 1493964437 ISBN-13(EAN): 9781493964437 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This collection seeks to elucidate the practical methods necessary for successful adjuvant development, with a particular focus on the synthesis, formulation, manufacturing, and characterization aspects involved. Beginning with an overview and a case study, the book then delves into in silico design, chemical synthesis, biosynthesis, and/or purification from natural raw materials of specific adjuvant molecules, adjuvant formulation approaches, the analytical characterization of adjuvant formulations and adjuvant-containing vaccines, as well as the biological characterization of vaccine adjuvant activity, including in vitro and in vivo approaches, to measure innate and adaptive immune responses. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Practical and authoritative, Vaccine Adjuvants: Methods and Protocols aims to facilitate vaccine adjuvant product development efforts, making them more accessible, manufacturable, and better characterized.
Автор: Charles J. Hackett; Donald A. Harn Jr Название: Vaccine Adjuvants ISBN: 1617372404 ISBN-13(EAN): 9781617372407 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use.
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