The Cytoskeleton, Thomas W. Clarkson; Polly R. Sager; Tore L.M. Syve

Автор: Philippe Jeanteur
Название: Cytoskeleton and Small G Proteins
ISBN: 3642636594 ISBN-13(EAN): 9783642636592
Издательство: Springer
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Описание: Animal cells present an extreme variability in their shapes in relation to their physiological properties. For instance, fibroblastic cells are tightly attached to the extra-cellular matrix and display a flattened, spindle-shaped morphology. Neuronal cells self-organize as a network through a complex branching of dendrites and a long axonal extension. Resting peripheral blood lymphocytes are poorly adhesive and maintain a spherical, smooth shape, while macroph- ages produce many pseudopodal extensions involved in the recognition of foreign molecules. In addition to the variability of the morphology of the cells that constitute different organs, many cell types also modify dynamically their morphology in response to environmental changes, leading to differential cell motility, migration, adhesion, polarity or intercellular contacts. This wide plasticity of cell morphology is promoted and maintained by the cytoskeleton, which is composed of the three interconnected actin micro filaments, tubulin microtubules and intermediate filaments networks, all capable of assembly and disassembly. Over the past few years, the Rho family of Ras-like GTPases emerged as key proteins that mediate extracellular signalling pathways leading to the forma- tion of polymerized actin-containing structures such as ruffles, lamellipodia and filopodia. Since the discovery of the first member RhoA in 1985, 13 mem- bers have so far been characterized in human cells. Most of Rho proteins are highly conserved between species as distant as yeast, slime mold, insects and mammals, which points to their fundamental role in cellular physiology.

Автор: Jerry Shay
Название: The Cytoskeleton
ISBN: 1468445944 ISBN-13(EAN): 9781468445947
Издательство: Springer
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Цена: 6986.00 р.
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Автор: Kermit L. Carraway; Coralie A. C. Carraway; Kermit
Название: Signaling and the Cytoskeleton
ISBN: 3662129957 ISBN-13(EAN): 9783662129951
Издательство: Springer
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Цена: 6986.00 р.
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Описание: This monograph explores the relationships between cell signaling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between two very active aspects of molecular cell biology.

Автор: Gerhard Isenberg
Название: Cytoskeleton Proteins
ISBN: 3642489613 ISBN-13(EAN): 9783642489617
Издательство: Springer
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Цена: 6986.00 р.
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Описание: The standard protocols for the purification of all known cytoskeleton proteins are presented in this manual. The isolation procedure for each protein is shown in a clear flowchart, while the source of the protein, equipment and material needed, a list of suppliers, standard references, accession No.

Автор: Ray H. Gavin
Название: Cytoskeleton Methods and Protocols
ISBN: 1617796492 ISBN-13(EAN): 9781617796494
Издательство: Springer
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Цена: 20263.00 р.
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Описание: In this cutting-edge book, internationally renowned experts present techniques which reflect many of the recent technological advances in experimental tools for cytoskeleton research. There is emphasis on animal, plant, protist, and fungal model systems.

Автор: Brigitte M. Jockusch; Eckhard Mandelkow; Klaus Web
Название: The Cytoskeleton
ISBN: 364279484X ISBN-13(EAN): 9783642794841
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Molecular biology has dissected the functional domains of the motor proteins involved and provided material required for biochemical studies as well as structure analysis by X-ray diffraction and NMR.

Автор: Philippe Jeanteur
Название: Cytoskeleton and Small G Proteins
ISBN: 3540648089 ISBN-13(EAN): 9783540648086
Издательство: Springer
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Цена: 36197.00 р.
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Описание: This work focuses on a family of cellular proteins which transmit signals in the form of small molecules outside the cell, the Rho Ras-like GTPases, and examines their role in normal cellular processes and development. Also discussed are their roles in cancer formation and microbial pathogenesis.

Автор: Maria Kavallaris
Название: Cytoskeleton and Human Disease
ISBN: 1627038876 ISBN-13(EAN): 9781627038874
Издательство: Springer
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Цена: 26120.00 р.
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Описание: This book explores our emerging understanding of the molecular and cellular events that drive cytoskeletal mediated diseases including cancer, heart disease, myopathies and skin disorders, and reviews progress toward targeted therapies for treating them.

Автор: Manfred Schliwa
Название: The Cytoskeleton
ISBN: 3709176697 ISBN-13(EAN): 9783709176696
Издательство: Springer
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Цена: 15372.00 р.
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Описание: The term cytoskeleton has become firmly established in today`s scientific vocabulary. Since then, the modern field of research on the structural organization of the cytoplasm has turned into one of the most productive and rapidly expanding research areas in Cell Biology today.