Structure and Function in Excitable Cells, Donald Cheng
Автор: Steiner, Heinz Название: Handbook of Basal Ganglia Structure and Function,24 ISBN: 012802206X ISBN-13(EAN): 9780128022061 Издательство: Elsevier Science Рейтинг: Цена: 22738.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Handbook of Basal Ganglia Structure and Function, Second Edition, offers an integrated overview of the structural and functional aspects of the basal ganglia, highlighting clinical relevance. The basal ganglia, a group of forebrain nuclei interconnected with the cerebral cortex, thalamus, and brainstem, are involved in numerous brain functions, such as motor control and learning, sensorimotor integration, reward, and cognition.
These nuclei are essential for normal brain function and behavior, and their importance is further emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson's disease, Tourette's syndrome, Huntington's disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction.
This updated edition has been thoroughly revised to provide the most up-to-date account of this critical brain structure. Edited and authored by internationally acclaimed basal ganglia researchers, the new edition contains ten entirely new chapters that offer expanded coverage of anatomy and physiology, detailed accounts of recent advances in cellular/molecular mechanisms and cellular/physiological mechanisms, and critical, deeper insights into the behavioral and clinical aspects of basal ganglia function and dysfunction.
Автор: Piergiorgio Strata; Emilio Carbone Название: Mg2+ and Excitable Membranes ISBN: 3642756387 ISBN-13(EAN): 9783642756382 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The present book is the outcome of a symposium on magnesium and excitable membranes, held in September 1989 on the occasion of the 12th annual meeting of the European Neuroscience Associ- ation in Torino. Leading specialists from around the world met in order to discuss the physiological and clinical effects of magne- sium on excitable cells. Magnesium ions are known to playa key role in the regulation of a variety of cell functions and, as such, have been implicated in the control of neuronal excitability and cardiovascular diseases. In the last decade, the advent of new electro physiological techniques has provided important details on the modulatory action of mag- nesium on ion channels and the receptor proteins of neurotrans- mitters. Thus, in neuronal and muscle cells, extracellular and in- is shown to block ion passage through open tracellular magnesium channels in a voltage- and time-dependent manner. The mecha- nism appears to be common for voltage- and receptor-operated channels, and it is thought to be an important cofactor in the long-term potentiation of synaptic transmission, brain aging, and cardiac activity. Recent findings show that the action of internal magnesium has additional features. High and low affinity sites for internal magnesium are involved in the regulation of channel gat- ings and ion permeation. Biochemical studies suggest that internal magnesium interferes with G-protein subunits, GTP-ase activity, and second messengers involved in channel phosphorylation.
Автор: Craig John Benham; Stephen Harvey; Wilma K. Olson; Название: Mathematics of DNA Structure, Function and Interactions ISBN: 144190669X ISBN-13(EAN): 9781441906694 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The IMA was an ideal venue for the 2007-2008 IMA thematic year on Mathematics of Molecular and Cellular Biology. This work contains 15 papers contributed by workshop speakers, that overview mathematical approaches to the understanding of DNA structure and function, and the interaction of DNA with proteins that mediate vital life processes.
Описание: This book describes recent developments concerning structural, functional and possible therapeutic aspects of one particular CAM, the neural cell adhesion molecule (NCAM).
Автор: Craig John Benham; Stephen Harvey; Wilma K. Olson; Название: Mathematics of DNA Structure, Function and Interactions ISBN: 1461424526 ISBN-13(EAN): 9781461424529 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Nick Cozzarelli: A Personal Remembrance.- Mathematical Methods in Dna Topology: Applications to Chromosome Organization and Site-Specific Recombination.- Conformational Statistics of Dna and Diffusion Equations on The Euclidean Group.- Perspectives On DNA Looping.- Differences Between Positively and Negatively Supercoiled DNA that Topoisomerases May Distinguish.- Calibration of Tethered Particle Motion Experiments.- Difference Topology: Analysis of High-Order DNA-Protin Assemblies.- Useful Intrusions of DNA Topology Into Experiments on Protein-DNA Geometry.- Topological Analysis of DNA-Protein Complexes.- Closing the Loop on Protein-DNA Interactions: Interplay Between Shape and Flexibility in Nucleoprotein Assemblies Having Implications for Biological Regulation.- Four-Way Helical Junctions in DNA Molecules.- Micromechanics of Single Supercoiled DNA Molecules.- Flexibility Of Nucleosomes On Topologically Constrained DNA.- The Mathematics of DNA Sturcture, Mechanics, and Dynamics.- Paradox Regained: a Topological Coupling of Nuclesomal DNA Wrapping and Chromatin Fibre Coiling.- Statistical-Mechanical Analysis of Enzymatic Topological Transformations in DNA Molecules.
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