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Monoclonal Antibodies, Roger H. Kennett


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Автор: Roger H. Kennett
Название:  Monoclonal Antibodies
ISBN: 9781461575078
Издательство: Springer
Классификация:
ISBN-10: 1461575079
Обложка/Формат: Soft cover
Вес: 0.77 кг.
Дата издания: 30.03.2012
Язык: English
Издание: Softcover reprint of
Иллюстрации: Black & white illustrations, bibliography
Размер: 254 x 178 x 23
Читательская аудитория: General (us: trade)
Основная тема: Immunology
Подзаголовок: Hybridomas: A New Dimension in Biological Analyses
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: On August 7, 1975, Kohler and Milstein published in Nature (256:495) a report describing Continuous cultures of fused cells secreting antibody of predefined specificity. Their report has become a classic and has already had a profound effect on basic and applied research in biology and medicine. By the time the first Workshop on Lymphocyte Hybridomas (Current Topics in Microbiology and Im- munology 81, 1978) was held on April 3-5, 1978, in Bethesda, Maryland, investi- gators from many laboratories had made hybrids between plasmacytomas and spleen cells from immunized animals and had obtained monoclonal antibodies reacting with a broad variety of antigenic determinants. At the time Kohler and Milstein introduced this new technology, the editors of this volume were involved in the production of antisera against differentiation antigens (K. B. B. ), histocompatibility antigens (T. ]. McK. ), and human tumor- associated antigens (R. H. K. ). Because of the potential usefulness of monoclonal antibodies in these areas, we each began production of hybridomas and analysis of the resulting monoclonal reagents. One of the most interesting aspects of participation in the early stages of the development and application of hybrid- oma technology has been observing how the implications of the initial observa- tions gradually spread first among the practitioners of immunology and immu- nogenetics, and then to other areas of the biological sciences, such as developmental biology, biochemistry, human genetics, and cell and tumor biology.


Human Monoclonal Antibodies: Methods and Protocols

Автор: Michael Steinitz (Editor)
Название: Human Monoclonal Antibodies: Methods and Protocols
ISBN: 1627035850 ISBN-13(EAN): 9781627035859
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.

Monoclonal Antibodies

Автор: R. Gieseler; Johann H. Peters; G. K?hler; P. Debba
Название: Monoclonal Antibodies
ISBN: 3642745342 ISBN-13(EAN): 9783642745348
Издательство: Springer
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Цена: 18284.00 р.
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Описание: With contributions by numerous authors

Monoclonal Antibodies

Автор: Kresina
Название: Monoclonal Antibodies
ISBN: 0824781163 ISBN-13(EAN): 9780824781163
Издательство: Taylor&Francis
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Цена: 49764.00 р.
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Описание: Presents a sampling of new and novel approaches to the amelioration of musculoskeletal disease pathology, emphasizing prevention and therapy. Where applicable, these new technologies are focused on their application to human autoimmune diseases, but the volume mainly discusses and details the use of

Human Hybridomas and Monoclonal Antibodies

Автор: Edgar Engleman
Название: Human Hybridomas and Monoclonal Antibodies
ISBN: 1468449516 ISBN-13(EAN): 9781468449518
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Soon after Kohler and Milstein described the use of somatic cell hybridization for the production of murine monoclonal antibodies of desired specificity, this relatively simple technique became widely applied.

Therapeutic Antibodies

Автор: Antony S. Dimitrov (Ed.)
Название: Therapeutic Antibodies
ISBN: 1934115924 ISBN-13(EAN): 9781934115923
Издательство: Springer
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Цена: 30745.00 р.
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Описание: Presents a set of protocols for the discovery and development of therapeutic antibodies, featuring sections focusing on recombinant antigens, antibody libraries, antibody discovery, antibody engineering and antibody preclinical development. This work is suitable for those investigating and participating in this therapeutic market segment.

Manual of Diagnostic Antibodies for Immunohistology

Автор: Anthony S-Y. Leong
Название: Manual of Diagnostic Antibodies for Immunohistology
ISBN: 1841101001 ISBN-13(EAN): 9781841101002
Издательство: Cambridge Academ
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Цена: 26453.00 р.
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Описание: The rapid acceptance of immunohistochemistry as an important and even indispensable adjunct to morphological examination and diagnosis requires the modern anatomical pathology laboratory to be conversant with, and proficient in, immunostaining procedures, as well as methods of tissue processing and antigen retrieval and the underlying characteristics of the increasing number of antibodies and antisera available. This fully revised, expanded and updated edition provides a comprehensive list of antisera and monoclonal antibodies that have useful diagnostic applications in tissue sections and cell preparations. Various clones, which are commercially available to detect the same antigen, are listed and the sensitivities and specificities of the antibodies are discussed. Importantly, the authors, all pathologists with a wealth of experience in immunostaining procedures, provide fully referenced details and expert advice on each reagent, with the reader will find invaluable. Finally, the appendices provide easily accessible and clear summaries of selected antibody panels for specific diagnostic situations, details of heat-induced antigen/epitope retrieval (including the use of microwaves) and a useful reference to the websites of the main antibody suppliers.

Monoclonal antibodies / methods and protocols

Автор: Albitar Maher
Название: Monoclonal antibodies / methods and protocols
ISBN: 1588295672 ISBN-13(EAN): 9781588295675
Издательство: Springer
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Цена: 21661.00 р.
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Описание: Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein, and the use of antibodies and flow cytometry in the quantification of cell signaling proteins. Specific chapters describe how antibodies are used for the diagnosis and classification of hematologic diseases. Subsequent chapters examine the advantages and most recent advances of using bead-based immunoassays, including the ability of bead-based technology to multiplex and analyze several analytes simultaneously, and the use of beads in detecting fusion proteins resulting from chromosomal translocations. Concluding chapters provide additional examples of methodologies that employ monoclonal antibodies.Monoclonal Antibodies: Methods and Protocols provides descriptions of methods that cover a wide spectrum of applications in the field of monoclonal antibodies. This field will continue to expand and provide new and innovative techniques, not only in the laboratory, but also as a basis that complements targeted therapy.

Radiolabeled Monoclonal Antibodies for Imaging and Therapy

Автор: Suresh C. Srivastava
Название: Radiolabeled Monoclonal Antibodies for Imaging and Therapy
ISBN: 1468455400 ISBN-13(EAN): 9781468455403
Издательство: Springer
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Цена: 16979.00 р.
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Описание: The advent of hybridoma technology leading to the successful produc- tion of monoclonal antibodies against a variety of tumor-associated antigens has, during the last decade, provided a very powerful tool for research and clinical investigations.

Monoclonal Antibodies

Автор: Ritter
Название: Monoclonal Antibodies
ISBN: 0521425034 ISBN-13(EAN): 9780521425032
Издательство: Cambridge Academ
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Цена: 14730.00 р.
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Описание: Monoclonal antibodies have a very important and wide-ranging role in many areas of biomedical research and this volume is amongst the very first to combine technical and clinical aspects of the subject.

Monoclonal Antibodies

Автор: Shepherd
Название: Monoclonal Antibodies
ISBN: 0199637229 ISBN-13(EAN): 9780199637225
Издательство: Oxford Academ
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Цена: 13464.00 р.
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Описание: This text covers the preparation, testing, derivation and application of monoclonal antibodies. Modern immunological techniques incorporating tried and tested methodologies are described, as well as the standard somatic hybridization and recombinant techniques, including the use of phage libraries.


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