Nitric Oxide, B. Mayer

Автор: Benjamin Bonavida
Название: Nitric Oxide (NO) and Cancer
ISBN: 1461426111 ISBN-13(EAN): 9781461426110
Издательство: Springer
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Цена: 41787.00 р.
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Описание: The Nobel Prize in Physiology and Medicine was awarded in 1998 to Doctors Furchgott, Ignarro, and Murad for their discoveries concerning "Nitric oxide (NO) as a signaling molecule in the cardiovascular system." NO-inducing cell signaling events within the cell producing it and the diffusibility to NO in other cells have led to the discovery of many other physiological functions in many different types of cells including cancer. Noteworthy, nitroglycerin that has been used for the treatment of chest pain and associated cardiovascular diseases is currently being investigated for its therapeutic effect in clinical studies in patients with cancer. Further, several NO donor compounds have shown, in preclinical studies, anti-tumoral chemopreventive and therapeutic activities. "Nitric Oxide and Cancer: Prognosis, Prevention and Therapy", edited by Benjamin Bonavida, Ph.D., reviews several novel applications of NO in cancer, a new field that has rapidly gained credibility and understanding at the biochemical and molecular levels. The various chapters in this comprehensive volume (25 contributions), written by noted experts in the field, bring up-to-date our current understanding and prospective future clinical applications of NO.

Автор: Ignarro, Louis J.
Название: Nitric Oxide
ISBN: 0128042737 ISBN-13(EAN): 9780128042731
Издательство: Elsevier Science
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Цена: 31160.00 р.
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Описание: Nitric Oxide: Biology and Pathobiology, Third Edition, provides information on nitric oxide, a signaling molecule of key importance for the cardiovascular system that regulates blood pressure and blood flow to different organs. . With recent links to the role of nitric oxide in the expression of healthy benefits of controlled diet and aerobic exercise, and the reactions of nitric oxide that can impact cell signaling, this book provides a comprehensive resource during a time when increased research attention is being paid across the fields of pharmacology, biochemistry, cell and molecular biology, chemistry, immunology, neurobiology, immunology, nutrition sciences, drug development and the clinical management of both acute and chronic diseases.

Автор: Qing-Ping Zeng
Название: Artemisinin and Nitric Oxide
ISBN: 3662476878 ISBN-13(EAN): 9783662476871
Издательство: Springer
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Цена: 7685.00 р.
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Описание: This book discusses both the beneficial and harmful aspects of NO in biology and medicine, and also introduces the emerging discovery of artemisinin in antitumor, antibacterial infection, anti-inflammation, and antiaging contexts. In 1992 nitric oxide (NO) was voted “Molecule of the Year” by Science magazine, and the discovery of its physiological roles has led to Nobel Prize-winning work in neuroscience, physiology and immunology. The book explains why we should maintain a steady-state NO level that is derived from neuronal or epithelial NO synthase, and avoid the extremely high NO level resulting from inducible NO synthase. The book offers a valuable resource for medical chemists, clinicians, biologists and all those interested in health and disease.

Автор: N. Allon; S. Shapira; B.A. Weissman
Название: Biochemical, Pharmacological, and Clinical Aspects of Nitric Oxide
ISBN: 1461357772 ISBN-13(EAN): 9781461357773
Издательство: Springer
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Цена: 15672.00 р.
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Описание: A decade ago, for most scientists investigating various issues in life sciences the word "NO" was used in a negative context. NO is implicated in long-term potentiation (LPT), a principal process involved in memory consolidation and it is considered as the main biochemical substance responsible for penile erection.

Автор: Hilary Koprowski; Hiroshi Maeda
Название: The Role of Nitric Oxide in Physiology and Pathophysiology
ISBN: 3642791328 ISBN-13(EAN): 9783642791321
Издательство: Springer
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Цена: 16979.00 р.
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Описание: Nitric Oxide (NO) an endogenous free radical, has been shown recently to mediate several important biological effects. It plays a neuro-transmitter like role in vascular endothelium, a scond-messenger role in N-methyl-D-aspartate (NMDA) responsive neurons in the central nervous system (CNS), a neurotoxic role after its release from these neurons, and a cytotoxic role after its release by macrophages.
This volume reviews among other topics the basic chemistry and physical properties of S-nitrosothiols (RS-NO) and their biochemical mechanisms of action, NO synthase isozymes, NO synthase structure, mechanisms of NO synthesis, regulation of NOS expression and posttranslational modification, and mechanisms involving NO of CNS's damage in virus infections.