Автор: H.A. Braun; J. Bligh; K. Br?ck; K. Voigt; G. Heldm Название: Thermoreception and Temperature Regulation ISBN: 3642750788 ISBN-13(EAN): 9783642750786 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As indicated in the Preface, the contributions to this volume are based upon the papers presented at the symposium on Thermoreceptors and Temperature Regula- tion held in July 1988 at the Institute of Physiology of the University of Marburg (Federal Republic of Germany) to celebrate and commemorate the life and achievements of HERBERT HENSEL, who directed that Institute from 1955 until his death in 1983, and whose most notable and significant contributions to thermo- physiology were in the areas of the properties and characteristics of thermo sensors, mammalian thermoregulation more generally, and the psychophysiology of ther- mal sensation. All the papers in this volume deal, to a greater or lesser extent, with these discernibly different but closely allied aspects of mammalian physiology. The editors have sought to achieve cohesion, flow, and balance both in the contributed articles and in their order of presentation, without either large gaps or redundancies in the coverage of the recent advances in the understanding of thermoreceptors and thermoregulation. At the same time we have sought to avoid such a degree of editorial control as to destroy the individuality of the contributions, and the judgements upon which they were based. We have also sought to look both backwards and forwards, and to include some legitimate extension of the con- sideration of thermosensitivity and thermoregulation into such areas as climatic adaptation and fever. Hence the greater or lesser of the closeness of this series of papers to HERBERT HENSEL'S scientific interests.
Автор: Zhang Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells ISBN: 1607617684 ISBN-13(EAN): 9781607617686 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This cutting-edge text will be a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and exciting areas of research such as regenerative medicine and cancer.
Автор: K.M.J. Menon, PhD; Aaron Goldstrohm, PhD Название: Post-transcriptional Mechanisms in Endocrine Regulation ISBN: 3319251228 ISBN-13(EAN): 9783319251226 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones.
Автор: Sajal Chakraborti; Naranjan S Dhalla Название: Regulation of Ca2+-ATPases,V-ATPases and F-ATPases ISBN: 3319247786 ISBN-13(EAN): 9783319247786 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The three main types of the ion pump ATPase family are: (i) P-type ATPases that transport different ions across membranes and Ca2+ATPases belongs to this catagory (ii) F-type ATPase in mitochondria, chloroplasts and bacterial plasma membranes produce ATP using the proton gradient;
Автор: Jagdish N. Sharma Название: Recent Developments in the Regulation of Kinins ISBN: 331906682X ISBN-13(EAN): 9783319066820 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent Developments in the Regulation of Kinins
Автор: Sajal Chakraborti; Naranjan S Dhalla Название: Regulation of Membrane Na+-K+ ATPase ISBN: 3319247484 ISBN-13(EAN): 9783319247489 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Na+-K+ ATPase or Na-pump ATPase, a member of “P”-type ATPase superfamily, is characterized by association of multiple isoforms mainly of it’s ?- and ?- subunits. At present four different ?- (?-1,?-2,?-3 and ?-4) and three ?- (?-1, ?-2, and ?-3) isoforms have been identified in mammalian cells and their differential expressions are tissue specific. Regulation of Na+-K+ ATPase activity is an important but a complex process, which involves short-term and long-term mechanisms. Short-term regulation of Na+-K+ ATPase is either mediated by changes in intracellular Na+ concentrations that directly affect the Na+-pump activity or by phosphorylation/dephosphorylation-mediated by some stimulants leading to changes in its expression and transport properties. On the other hand, long-term regulation of Na+-K+ ATPase is mediated by hormones, such as mineralocorticoids and thyroid hormones, which cause changes in the transcription of genes of ?- and ?- subunits leading to an increased expression in the level of Na+-pump. Several studies have revealed a relatively new type of regulation that involves the association of small, single span membrane proteins with this enzyme. These proteins belong to the FXYD family, the members of which share a common signature sequence encompassing the transmembra ne domain adjacent to the isoform(s) of ?-? subunits of Na+-K+ ATPase. Considering the extraordinary importance of Na+-K+ ATPase in cellular function, several internationally established investigators have contributed their articles in the monograph entitled “Regulation of Membrane Na+-K+ ATPase” for inspiring young scientists and graduate students to enrich their knowledge on the enzyme, and we are sure that this book will soon be considered as a comprehensive scientific literature in the area of Na+-K+ ATPase regulation in health and disease.
Описание: Relates the biological phenomena to the underlying biochemical processes. Aimed at advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis.
Автор: Armen Parsyan Название: Translation and Its Regulation in Cancer Biology and Medicine ISBN: 9401790779 ISBN-13(EAN): 9789401790772 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book, for the first time, comprehensively assembles and analyzes a large body of information on the role of the fundamental mechanism of the protein biosynthesis pathway, translation, in cancer biology. It systematically explores the function of the translation machinery and its regulation, including cell signaling, in the development, maintenance and progression of human cancer. The work presented here unveils the tremendous potential and applications of this vast and exciting branch of genetic, biochemical and molecular science in cancer medicine and drug development. Chapters contributed by experts in the field take the reader on a journey that starts with a dissection of the translation machinery and its regulation in norm and cancer. Later chapters characterize etiological and pathogenetic roles that translation plays in specific cancer types. Various aspects of diagnostic, prognostic and therapeutic significance of the translation machinery and its control in cancer are discussed. Readers will discover the importance of the process of translation and its regulatory mechanisms in physiology and cancer biology. The chapters and the numerous illustrations included here were contributed by expert scientists and clinicians from renowned academic and clinical establishments in Canada, the United States of America, the United Kingdom, Italy, France, Belgium, Spain, Germany and Australia. The book conveys information and knowledge that may interest a broad range of students and scholars ranging from basic scientists to clinicians and drug developers seeking to better understand the protein synthesis and its aberrations in cancer biology and cancer medicine.
Автор: Eva-Mari Aro; B. Andersson Название: Regulation of Photosynthesis ISBN: 9401741468 ISBN-13(EAN): 9789401741460 Издательство: Springer Рейтинг: Цена: 46118.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers the expression of photosynthesis related genes including regulation both at transcriptional and translational levels. It reviews biogenesis, turnover, and senescence of thylakoid pigment protein complexes and highlights some crucial regulatory steps in carbon metabolism.
Автор: Robert F. Goldberger; Keith R. Yamamoto Название: Biological Regulation and Development ISBN: 1475746210 ISBN-13(EAN): 9781475746211 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The motivation for us to conceive this series of volumes on regulation was mainly our belief that it would be fun, and at the same time productive, to approach the subject in a way that differs from that of other treatises. We thought it might be interesting and instructive for both author and reader-to examine a particular area of investigation in a framework of many different problems. Cutting across the traditional boundaries that have separated the subjects in past volumes on regulation is not an easy thing to do-not because it is difficult to think of what interesting topics should replace the old ones, but because it is difficult to find authors who are willing to write about areas outside those pursued in their own laboratories. Anyone who takes on the task of reviewing a broad area of interest must weave together its various parts by picking up the threads from many different laboratories, and attempt to produce a fabric with a meaningful design. Finding persons who are likely to succeed in such a task was the most difficult part of our job. In the first volume of this treatise, most of the chapters dealt with the mechanisms of The second volume involved a somewhat regulation of gene expression in microorganisms. broader area, spanning the prokaryotic-eukaryotic border. Topics ranged from phage mor phogenesis to the role of gradients in development. The last volume-Volume 3A-con cerned hormones, as does this volume-Volume 3B.
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