Anticancer Drug Development Guide, Beverly A. Teicher
Автор: Teicher Название: Anticancer Drug Development Guide. 2ed.2004 ISBN: 1588292282 ISBN-13(EAN): 9781588292285 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This thoroughly updated and expanded second edition of Beverly Teicher's widely used classic survey provides a step-by-step guide to anticancer drug development from initial design through FDA approval. The authors have included new material on the use of high throughput screening in industry, on specialized in vitro/in vivo procedures employed by the National Cancer Institute (NCI) in preclinical drug evaluations, and on nonclinical testing to support both human clinical trials, as well as trials of biologic oncology products. The chapters on phase I, II, and III clinical trials and on novel phase II clinical trial designs for targeted therapies have been significantly updated, along with those on cancer drug development in Europe, working with the NCI, and the FDA's role in cancer drug development and setting requirements for approval.
Описание: This book is a comprehensive survey of all families of anticancer agents and therapeutic approaches. The book will acts as an indispensable resource for researchers, medicinal chemists and biomedical scientists. The new edition of this book will also have a Companion Website.
Автор: Benjamin Winograd; Michael Peckham; Herbert M. Pin Название: Human Tumour Xenografts in Anticancer Drug Development ISBN: 3642732542 ISBN-13(EAN): 9783642732546 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Seminar on Human Tumour Xenografts 1986, Milan, Italy. European School of Oncology
Автор: Kunnumakkara Ajaikumar B Название: Anticancer Properties Of Fruits And Vegetables: A Scientific Review ISBN: 9814508888 ISBN-13(EAN): 9789814508889 Издательство: World Scientific Publishing Рейтинг: Цена: 20592.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An Estimated 12.6 Million People Are Diagnosed With Cancer Every Year And 7.6 Million People Die Of The Disease Annually. Numerous Lines Of Evidence Suggest That Lifestyle And Nutrition Play An Important Role In Cancer Development. As For Nutrition, Diets That Are Rich In Fruits And Vegetables Have Been Shown To Lower The Risk Of Cancer Incidence. In Addition, Several Phytochemicals That Are Present In Fruits And Vegetables Have Been Scientifically Established To Have Properties That Can Prevent And Treat This Malevolent Disease.The Primary Aim Of The Book Is To Educate The Public About The Benefits Of Fruits And Vegetables As They Relate To Cancer And Their Potential To Contribute To The Possibility Of A Cancer-Free Life. The Active Ingredients And Modes Of Actions Of Fruits And Vegetables Are Also Discussed, Along With Their Chemo-Preventive Aspects.This Clearly Written, Comprehensive Guide Explains The Properties Of These Natural Foods And Substances On A Cancer-By-Cancer Basis. Thus, This Book Not Only Informs The General Public About The Anticancer Properties Of Fruits And Vegetables But Also Provides A Valuable Reference For Scientists And Other Professionals Working In This Area.
Автор: Carmen Avendano Название: Medicinal Chemistry of Anticancer Drugs ISBN: 0444626492 ISBN-13(EAN): 9780444626493 Издательство: Elsevier Science Рейтинг: Цена: 23244.00 р. Наличие на складе: Поставка под заказ.
Описание: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. . Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. . Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design.
Автор: Elizabeth Garrett-Mayer; Manuel Hidalgo; S. Gail E Название: Principles of Anticancer Drug Development ISBN: 1461427916 ISBN-13(EAN): 9781461427919 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is a practical guide to the design, conduction, analysis and reporting of clinical trials with anticancer drugs. It includes coverage of basic biostatistics for the clinical trialist, and fundamental concepts in clinical pharmacology.
Автор: Soodabeh Saeidnia Название: New Approaches to Natural Anticancer Drugs ISBN: 3319140264 ISBN-13(EAN): 9783319140261 Издательство: Springer Рейтинг: Цена: 7685.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an up-to-date review of recently identified natural anti-tumor compounds from various natural origins including plants, fungi, endophytic fungi and marine organisms. It also includes discussion of new areas such as biotechnology and nanoparticles. Chapters explain the challenges and developments in anti-cancer drug discovery approaches, traditional remedies for prevention and treatment of cancer, marine-derived anti-cancer compounds, and antibiotics used as anti-cancer agents, as well as different classes of terpenoids and carbohydrates, which have been the subject of discussion in this field as efficient anti-cancer candidates. This book will be a concise guide for researchers in the field of pharmaceutical sciences, students and residents in pharmacy and medicine as well as those researching phytochemistry and natural products.
Автор: Muriel, Le Roux Название: Anticancer Drugs: Navelbine(R) and Taxotere(R) ISBN: 1785481452 ISBN-13(EAN): 9781785481451 Издательство: Elsevier Science Рейтинг: Цена: 16001.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Among the many forms of cancer treatment, chemotherapy remains an important part of the arsenal in which Navelbine and Taxotere play a major role.These medicines result from molecules discovered by French researchers of the Institut de Chimie des Substances Naturelles (ICSN) of the CNRS, directed by Pierre Potier. By recounting this history, the authors of this book attempt to illustrate how the work of themselves and others, united in a community, has helped obtain these results. After having explained the strategy of the French policy makers to promote the French chemistry of natural substances, the authors explore how the academic efforts in this field have evolved, and the alignment between science and its applications has become increasingly present. The contributions of the CNRS to the industry, and vice versa, offer an alternative image of public research relationships and industrial research, where CNRS researchers are able to extend the limits of freedom and creativity. It is to account for this complexity that the authors here have chosen to write this history together, which is in a sense exemplary.Due to an association between history and chemistry, this book explains these discoveries by placing them in their specific politic, economic and scientific contexts.
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