Transporters in Drug Development, Yuichi Sugiyama; Bente Steffansen
Автор: Susan Napier; Matilda Bingham Название: Transporters as Targets for Drugs ISBN: 3642099696 ISBN-13(EAN): 9783642099694 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In each volume of Transporters as Targets for Drugs an overview chapter introduces the newcomer to the topic covered. The series covers hot topics of frontier research summarized by reputed scientists in the field.
Автор: Thomas Efferth Название: Resistance to Targeted ABC Transporters in Cancer ISBN: 3319098004 ISBN-13(EAN): 9783319098005 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This critical review volume explores the theme of ABC transporters in the context of basic cancer research and its role in drug-resistant tumors. The chapters provided complement basic research by including investigations from translational applications to clinical oncology. The development of resistance is a major obstacle in cancer chemotherapy and the field has been moving rapidly in terms of determining the mechanisms for blocking ABC transporter-mediated drug efflux by specific inhibitors and thereby overcoming multidrug resistance. The volume covers these issues in careful detail. Additional topics include the relevance of ABC transporters in resistance to novel and established anticancer drugs and prognosis of patients to compounds, compounds used in photodynamic therapy, tyrosine kinase inhibitors and others. Furthermore, the potential of radiopharmaceuticals for diagnosis of multidrug-resistant tumors and of nanotechnology to combat drug-resistant tumors is also discussed.
Описание: By guiding in the application of techniques and tools for predicting ADMET outcomes in drug candidates, Predictive ADMET offers a road map for drug discovery scientists to generate effective and safe drugs for unmet medical needs.
Автор: Semizarov, Dimitri Blomme, Eric Название: Genomics in drug discovery and development ISBN: 0470096047 ISBN-13(EAN): 9780470096048 Издательство: Wiley Рейтинг: Цена: 22168.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Early characterization of toxicity and efficacy would significantly impact the overall productivity of pharmaceutical R&D and reduce drug candidate attrition and failure.
Автор: Wang Название: Biological Drug Products: Development and Strategies ISBN: 1118148894 ISBN-13(EAN): 9781118148891 Издательство: Wiley Рейтинг: Цена: 24544.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book overviews the fundamental aspects, challenges, and strategies for developing a variety of biological drugs -- a large and growing segment of the pharmaceutical industry. Contributing authors discuss the development process, safety and clinical assessments, manufacturing, regulatory and intellectual property issues.
Автор: Uday B. Kompella; Henry F. Edelhauser Название: Drug Product Development for the Back of the Eye ISBN: 146142819X ISBN-13(EAN): 9781461428190 Издательство: Springer Рейтинг: Цена: 32651.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Selection of Drug Delivery Approaches for the Back of the Eye: Opportunities and Unmet Needs.- Microdialysis for Vitreal Pharmacokinetics.- Fluorophotometry for Pharmacokinetic Assessment.- Systemic Route for Retinal Drug Delivery: Role of the Blood-Retinal Barrier.- Topical Drug Delivery to the Back of the Eye.- Principles of Retinal Drug Delivery from Within the Vitreous.- Transscleral Drug Delivery.- Suprachoroidal and Intrascleral Drug Delivery.- Advances in Biodegradable Ocular Drug Delivery Systems.- Microparticles as Drug Delivery Systems for the Back of the Eye.- Nanotechnology and Nanoparticles.- Hydrogels for Ocular Posterior Segment Drug Delivery.- Refillable Devices for Therapy of Ophthalmic Diseases.- Targeted Drug Delivery to the Eye Enabled by Microneedles.- Ocular Iontophoresis.- Drug and Gene Therapy Mediated by Physical Methods.- Protein Drug Delivery and Formulation Development.- Drug Suspension Development for the Back of the Eye.- Regulatory Considerations in Product Development for Back of the Eye.- Clinical Endpoints for Back of the Eye Diseases.- Druggable Targets and Therapeutic Agents for Disorders of the Back of the Eye.- Development of Bile Acids as Anti-Apoptotic and Neuroprotective Agents in Treatment of Ocular Disease.
Автор: Naitee Ting Название: Dose Finding in Drug Development ISBN: 144192115X ISBN-13(EAN): 9781441921154 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: If you have ever wondered when visiting the pharmacy how the dosage of your prescription is determined this book will answer your questions. It introduces the drug development process and explains the practical concerns in selecting doses for a new drug.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
