Описание: Large-section histopathology widens your perspectives...Correct diagnosis and staging are essential in determining the appropriate therapy of colorectal carcinoma, one of the most common malignancies in America and Europe. As medical science continues to develop rapidly, histopathology remains an essential part of diagnosis in most malignant diseases. In this era of interdisciplinary medicine, the role of pathology has expanded to provide images that easily correlate with endoscopic, radiological, or operative findings.In this remarkable atlas, Tibor Tot presents colon pathology in large histological sections, with cross-sections of entire tumors in their anatomic environments and their circumferential surgical margins. These unique images form a guide to diagnosis, tumor typing and staging according to TNM criteria. They help to assess the completeness of a surgical excision and to understand the heterogeneity of colorectal carcinomas. Features:- Cases illustrated in two-page spreads with clinical information, conventional histopathology, and large-section histology images enlarged to almost a full page. - Pathology seen in the context of surrounding tissues- The margins of malignant tumors visible in their entirety- Schematic guides to interpretation of the large-section images - Emphasis on diagnostic advantages of using large section technique- Technical guidelines for obtaining large-section histopathology specimensThis atlas is the result of seven years of studying almost 2,000 cases of colorectal carcinoma and other intestinal lesions and is highly recommended for pathologists, radiologists, surgeons, and oncologists alike.
Автор: Beauchemin Название: Metastasis of Colorectal Cancer ISBN: 9048188326 ISBN-13(EAN): 9789048188321 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers colon cancer metastasis from fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, and more.
Автор: Benjamin Bonavida Название: Nitric Oxide and Cancer: Pathogenesis and Therapy ISBN: 3319136100 ISBN-13(EAN): 9783319136103 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Advances in Nitric Oxide and Cancer is a volume that serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews significant advances in the application of NO-mediated drugs. The volume explores nitric oxide and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance to cytotoxics, and therapeutic applications. With chapters written by leading experts, the volume addresses the burgeoning interest in a rapidly advancing field and provides a valuable resource to scientists who have initiated research as well as clinical investigations in their laboratories on the various roles of NO and cancer.
Описание: Over the past decade, we have made great advances in the field of multiple sclerosis (MS) research, and this book focuses on those advances in MS pathogenesis and treatment. While some of these advances have been through new approaches and ideas that have emerged in the last decade such as the newly identified protective role that amyloid proteins may play in MS or the use of helminths to treat autoimmune diseases, others have evolved from previous theories and ideas that have only now gained momentum and a deeper understanding such as the role of HLA or gender in MS susceptibility. This book covers these emerging and evolving topics and highlights the substantial advancements made in elucidation of the factors regulating susceptibility or disease progression, identification of new ways to monitor or predict MS pathology, and development of new strategies for treating MS.
Автор: John J. Lemasters; Anna-Liisa Nieminen Название: Mitochondria in Pathogenesis ISBN: 1475786956 ISBN-13(EAN): 9781475786958 Издательство: Springer Рейтинг: Цена: 32652.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent research has shown that mitochondrial dysfunction underlies a broad spectrum of disease, from maternally inherited genetic disorders to metabolism defects, aging, stroke, and neurodegenerative diseases such as Parkinson`s, Alzheimer`s, and Lou Gehrig`s disease.
Автор: Gregory Название: Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy ISBN: 3319394045 ISBN-13(EAN): 9783319394046 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews.
Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.
Описание: With contributions from an interdisciplinary team of recognized experts, this illustrated volume reviews the diverse mechanisms-genetic, metabolic, and molecular-that give M. tuberculosis its antibiotic-resistant virulence and allow it to evade immune systems.
Автор: Hilbi Название: Molecular Mechanisms in Legionella Pathogenesis ISBN: 3642405908 ISBN-13(EAN): 9783642405907 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines different facets of Legionnaires` disease, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of effector proteins and cellular pathogen-host interactions, as well as host responses.
Автор: Isabelle Mercier; Jean-Fran?ois Jasmin; Michael P. Название: Caveolins in Cancer Pathogenesis, Prevention and Therapy ISBN: 1493901346 ISBN-13(EAN): 9781493901340 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Caveolins play an important role in the pathogenesis of multiple cancers. This volume focuses mainly on the importance of Caveolin-1 in breast, prostate, lung, skin, colon, pancreatic and brain cancers. It also studies the role of Caveolin-3 in breast cancer.
Автор: Nathanson Название: Viral Pathogenesis and Autoimmunity.2002 ISBN: 0781711037 ISBN-13(EAN): 9780781711036 Издательство: Lippincott Williams & Wilkins Цена: 8237.00 р. Наличие на складе: Поставка под заказ.
Описание: Written by eminent authorities on viral pathogenesis and immunity, this text provides a coherent, concise introduction to the field. The authors focus on fundamental principles and present a well-organized overview that is easy for readers to absorb.Section 1, essentials of viral pathogenesis , describes the sequential events in viral infection, the localization of viral infections, and the variety of virus-cell interactions.Section 2, host responses to viral infection , examines immune responses, including virus-induced immunopathology and immunosuppression.Section 3, virus-host interactions , covers virulence, viral persistence, virus-induced oncogenesis, and host susceptibility.Section 4, prevention of viral infections , explains the key principles of vaccine development.
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