Systems Biology of Metabolic and Signaling Networks, Miguel A. Aon; Valdur Saks; Uwe Schlattner
Автор: Verpoorte R., Alfermann A.W., Johnson T.S. Название: Applications of Plant Metabolic Engineering ISBN: 1402060300 ISBN-13(EAN): 9781402060304 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Written by leading international experts in the field of plant metabolic engineering, this book discusses, mainly, applications of plant metabolic engineering. Metabolic engineering, which is part of second generation biotechnology, has made several contributions at basic level as well as at conceptualising products ever since its emergence in the early 1980s. Applications resulting from metabolic engineering are expected to play a very important role in future for plant breeding, e.g. for improved resistance or improved traits concerning health promoting constituents, and production of fine chemicals such as medicines, flavors and fragrances. Considering the tremendous progress that has been made since our first book in the year 2000 urgency was felt to bring together cutting edge research in plant metabolic engineering in applied aspects as a handy reference book. This book has been predominantly dedicated to applied research of metabolic engineering, and a part of it has been allotted for fundamental research that has potential applications. This book is a unique source of information for all those involved with plants as chemical factories of fine chemicals and also to more experienced scientists who work on transgenic plants, besides, senior researchers, graduate students, post-doctroral students, teachers and students as well.
Описание: This work reviews developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity in the production of polyketides and extension of the substrate range.
Автор: Gregory Stephanopoulos Название: Metabolic Engineering, ISBN: 0126662606 ISBN-13(EAN): 9780126662603 Издательство: Elsevier Science Рейтинг: Цена: 25054.00 р. Наличие на складе: Поставка под заказ.
Описание:
Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes.
Key features of the book are pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps mathematical complexity to a minimum, and provides a glossary of biological terms to facilitate use of the book by a broader spectrum of readers. A web page exists to communicate updates of the codes and homework problems.
Автор: Kauffman Alexander S Название: Kisspeptin Signaling in Reproductive Biology ISBN: 1461461987 ISBN-13(EAN): 9781461461982 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on kisspeptin and its role in reproductive biology. It looks at interactions between Kisspeptin and Neurokinin B and reviews model systems for studying kisspeptin signaling.
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Synthetic Biology and Metabolic Engineering in Plants and Microbes: Part A," the new volume in the "Methods in Enzymology" series, " "continues the legacy of this premier serial with quality chapters authored by leaders in the field.
This volume covers research methods, synthetic biology, and metabolic engineering in plants and microbes, and includes sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Contains two volumes covering research methods in synthetic biology and metabolic engineering in plants and microbesPresents sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways
Описание: Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation.
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