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Next Generation Sequencing Technologies and Challenges in Sequence Assembly, Sara El-Metwally; Osama M. Ouda; Mohamed Helmy


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Автор: Sara El-Metwally; Osama M. Ouda; Mohamed Helmy
Название:  Next Generation Sequencing Technologies and Challenges in Sequence Assembly
ISBN: 9781493907144
Издательство: Springer
Классификация:


ISBN-10: 149390714X
Обложка/Формат: Soft cover
Страницы: 130
Вес: 0.21 кг.
Дата издания: 19.04.2014
Серия: SpringerBriefs in Systems Biology
Язык: English
Иллюстрации: 1 illustrations, color; 11 illustrations, black and white; xii, 118 p. 12 illus., 1 illus. in color.
Размер: 234 x 156 x 7
Читательская аудитория: Professional & vocational
Основная тема: Systems Biology
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field. This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges.
Дополнительное описание: Basics of Molecular Biology for Next-generation Sequencing.- Algorithms and Data Structures in Next-generation Sequencing.- First- and Next-generations Sequencing Models.- Next-generation Sequencing Platforms.- Challenges in Next-generation Sequencing Fie



Clinical Applications for Next Generation Sequencing

Автор: Urszula Demkow
Название: Clinical Applications for Next Generation Sequencing
ISBN: 0128017392 ISBN-13(EAN): 9780128017395
Издательство: Elsevier Science
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Цена: 12462.00 р.
Наличие на складе: Поставка под заказ.

Описание:

Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments.

Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients.

The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia.

Next Generation Sequencing in Cancer Research

Автор: Wei Wu; Hani Choudhry
Название: Next Generation Sequencing in Cancer Research
ISBN: 1461476445 ISBN-13(EAN): 9781461476443
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book offers an interdisciplinary perspective on applying Next Generation Sequencing (NGS) technology to cancer research, surveying the foundations of the technology and its implications in cancer biology, and introducing single cancer cell sequencing.

Field Guidelines for Genetic Experimental Designs in High-Throughput Sequencing

Автор: Aransay
Название: Field Guidelines for Genetic Experimental Designs in High-Throughput Sequencing
ISBN: 3319313487 ISBN-13(EAN): 9783319313481
Издательство: Springer
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Цена: 23508.00 р.
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Описание: High throughput sequencing (HTS) technologies have conquered the genomics and epigenomics worlds. The applications of HTS methods are wide, and can be used to sequence everything from whole or partial genomes, transcriptomes, non-coding RNAs, ribosome profiling, to single-cell sequencing. Having such diversity of alternatives, there is a demand for information by research scientists without experience in HTS that need to choose the most suitable methodology or combination of platforms and to define their experimental designs to achieve their specific objectives. Field Guidelines for Genetic Experimental Designs in High-Throughput Sequencing aims to collect in a single volume all aspects that should be taken into account when HTS technologies are being incorporated into a research project and the reasons behind them. Moreover, examples of several successful strategies will be analyzed to make the point of the crucial features. This book will be of use to all scientist that are unfamiliar with HTS and want to incorporate such technologies to their research.

Multiple Biological Sequence Alignment - Scoring Functions, Algorithms and Applications

Автор: Nguyen
Название: Multiple Biological Sequence Alignment - Scoring Functions, Algorithms and Applications
ISBN: 1118229045 ISBN-13(EAN): 9781118229040
Издательство: Wiley
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Цена: 15198.00 р.
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Описание: Covers the fundamentals and techniques of multiple biological sequence alignment and analysis, and shows readers how to choose the appropriate sequence analysis tools for their tasks This book describes the traditional and modern approaches in biological sequence alignment and homology search.

Sequence Analysis Primer (Paperback)

Автор: Gribskov, Michael; Devereux, John
Название: Sequence Analysis Primer (Paperback)
ISBN: 0195098749 ISBN-13(EAN): 9780195098747
Издательство: Oxford Academ
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Цена: 19404.00 р.
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Описание: This book enables researchers to understand and maximize the use of computerized sequence analysis in biotechnological research. Compatible with most sequence analysis programs, the primer covers basic data manipulation, and offers valuable advice for overcoming common problems.

Sequence Comparison

Автор: Kun-Mao Chao; Louxin Zhang
Название: Sequence Comparison
ISBN: 1849967822 ISBN-13(EAN): 9781849967822
Издательство: Springer
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Цена: 19564.00 р.
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Описание: Biomolecular sequence comparison is the origin of bioinformatics. This book gives a complete in-depth treatment of the study of sequence comparison. The book examines alignment methods and techniques, and features a new issue of sequence comparison.

Next Generation Sequencing

Автор: Lee-Jun C. Wong
Название: Next Generation Sequencing
ISBN: 1461470005 ISBN-13(EAN): 9781461470007
Издательство: Springer
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Цена: 30745.00 р.
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Описание: This book examines next generation sequencing applications. It details current technologies, various gene enrichment methods and massively parallel sequencing platforms, potential limitations, and the application of these technologies.


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