Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases, Michael B. A. Oldstone; Hugh Rosen

Название: Apoptosis, Cell Signaling & Human Diseases. Vol2. 2007
ISBN: 1588298825 ISBN-13(EAN): 9781588298829
Издательство: Springer
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Цена: 28734.00 р.
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Описание: Provides developments in cell survival and apoptotic pathways and their involvement in various human diseases. This book contains 31 chapters which have been divided into four sections: Malignant Transformation and Metastasis; Kinases and Phosphatases; Molecular Basis of Cell Death; and Molecular Basis of Disease Therapy.

Автор: Moshe Oren; Yael Aylon
Название: The Hippo Signaling Pathway and Cancer
ISBN: 1461462193 ISBN-13(EAN): 9781461462194
Издательство: Springer
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Цена: 26122.00 р.
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Описание: ГЇВїВЅ ГЇВїВЅ This book ГЇВїВЅ explores virtually all aspects of tumor biology in relation to the Hippo Pathway. It gathers wide-ranging and burgeoning information into an accessible format and features timely research from leading scientists in the field.

Автор: Backert
Название: Inflammasome Signaling and Bacterial Infections
ISBN: 3319411705 ISBN-13(EAN): 9783319411705
Издательство: Springer
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Цена: 22203.00 р.
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Описание: This volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and highlights their action, in particular in response to infection with important bacterial model organisms and the corresponding disease pathologies. The first chapters review new insights into the assembly and structures of inflammasome components and emphasize general strategies of up- and downstream signaling events. In addition, the authors specifically discuss the composition and activity of inflammasomes during infection with various gut pathogens (Salmonella, Shigella, Yersinia, Listeria and Helicobacter), respiratory pathogens (Mycobacterium, Legionella, Burkholderia and Streptococcus) as well as skin and soft tissue pathogens (Francisella and Staphylococcus). The discoveries presented provide a better understanding of the cellular and molecular biology of inflammasomes, which will pinpoint important new therapeutic targets for the treatment and prevention of multiple infectious diseases in the future. It is a valuable resource for students, scientists and clinicians, providing up-to-date information on this emerging research topic.

Автор: Tomohiro Kurosaki; J?rgen Wienands
Название: B Cell Receptor Signaling
ISBN: 3319261312 ISBN-13(EAN): 9783319261317
Издательство: Springer
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Цена: 18284.00 р.
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Описание: Altogether, the discoveriespresented provide a better understanding of B cell biology and help to explainsome B cell-mediated pathogenicities, like autoimmune phenomena or theformation of B cell tumors, while also paving the way for eventually combating thesediseases.

Автор: Gerard Pasterkamp
Название: Semaphorins: Receptor and Intracellular Signaling Mechanisms
ISBN: 1441924272 ISBN-13(EAN): 9781441924278
Издательство: Springer
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Цена: 32004.00 р.
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Описание: This book details our progress in understanding the receptor and intracellular signaling mechanisms utilized by semaphorins. The comprehensive overview of semaphorin biology and signaling presented in this book allows one to compare semaphorin functions between different biological systems.