A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems, Vishwesh V. Kulkarni; Guy-Bart Stan; Karthik Raman
Описание: A Systems Theoretic Approach to Systems and Synthetic Biology I: Models and System Characterizations
Название: Systems biology approach to blood ISBN: 1493920944 ISBN-13(EAN): 9781493920945 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The blood system is multi-scale, from the organism to the organs to cells to intracellular signaling pathways to macromolecule interactions. Blood consists of circulating cells, cellular fragments (platelets and microparticles), and plasma macromolecules. Blood cells and their fragments result from a highly-ordered process, hematopoiesis. Definitive hematopoiesis occurs in the bone marrow, where pluripotential stem cells give rise to multiple lineages of highly specialized cells. Highly-productive and continuously regenerative, hematopoiesis requires a microenvironment of mesenchymal cells and blood vessels. A Systems Biology Approach to Blood is divided into three main sections: basic components, physiological processes, and clinical applications. Using blood as a window, one can study health and disease through this unique tool box with reactive biological fluids that mirrors the prevailing hemodynamics of the vessel walls and the various blood cell types. Many blood diseases, rare and common can and have been exploited using systems biology approaches with successful results and therefore ideal models for systems medicine. More importantly, hematopoiesis offers one of the best studied systems with insight into stem cell biology, cellular interaction, development; linage programing and reprograming that are every day influenced by the most mature and understood regulatory networks.
Описание: Much of the work on analysis and synthesis problems relating to the multiple model approach has been motivated by the desire to establish the problems of control law synthesis and full state estimation in numerical terms. This book concentrates on the analysis of the stability and synthesis of control laws and observations for multiple models.
Описание: This edited volume contains a selection of chapters that are an outgrowth of the - ropean Conference on Mathematical and Theoretical Biology (ECMTB05, Dresden, Germany, July 2005). The peer-reviewed contributions show that mathematical and computational approaches are absolutely essential for solving central problems in the life sciences, ranging from the organizational level of individual cells to the dynamics of whole populations. The contributions indicate that theoretical and mathematical biology is a diverse and interdisciplinary ?eld, ranging from experimental research linked to mathema- cal modeling to the development of more abstract mathematical frameworks in which observations about the real world can be interpreted, and with which new hypotheses for testing can be generated. Today, much attention is also paid to the development of ef?cient algorithms for complex computation and visualisation, notably in molecular biology and genetics. The ?eld of theoretical and mathematical biology and medicine has profound connections to many current problems of great relevance to society. The medical, industrial, and social interests in its development are in fact indisputable.
Автор: Singh Название: Systems Biology Application in Synthetic Biology ISBN: 8132228073 ISBN-13(EAN): 9788132228073 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book introduces students to methods that will help them understand behaviour in terms of cellular components and their interactions in non-intuitive ways, which calls for an interdisciplinary approach combining mathematical, chemical, computational and biological strategies. Tibor Ganti was one of the early pioneers who proposed a theoretical framework to understand living principles in terms of chemical transformation cycles and their coupling. The twenty-first century then brought with it a novel ‘systems’ paradigm, which shone new light on all previous work and was accompanied by numerous implications for the way we conceive of chemical and biological complexity today. This book seeks to equip students to take advantage of any field that investigates living systems. Based on a conceptualisation of science-oriented branches, engineering-oriented branches and biology as astoundingly complex fields, those structures laden with biochemical detail encompass a deeper theory unifying our knowledge of designed systems. Readers will be pleasantly surprised at how lucidly the topics are presented. The book offers an indispensable resource for students and professionals working in systems and synthetic biology or any of the various related fields of research.
Автор: Vikram Singh; Pawan K. Dhar Название: Systems and Synthetic Biology ISBN: 9401795134 ISBN-13(EAN): 9789401795135 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This textbook has been conceptualized to provide a detailed description of the various aspects of Systems and Synthetic Biology, keeping the requirements of M.Sc. and Ph.D. students in mind. Also, it is hoped that this book will mentor young scientists who are willing to contribute to this area but do not know from where to begin. The book has been divided into two sections. The first section will deal with systems biology – in terms of the foundational understanding, highlighting issues in biological complexity, methods of analysis and various aspects of modelling. The second section deals with the engineering concepts, design strategies of the biological systems ranging from simple DNA/RNA fragments, switches and oscillators, molecular pathways to a complete synthetic cell will be described. Finally, the book will offer expert opinions in legal, safety, security and social issues to present a well-balanced information both for students and scientists.
Автор: Alexey Melkikh; Maria Sutormina Название: Developing Synthetic Transport Systems ISBN: 9400758928 ISBN-13(EAN): 9789400758926 Издательство: Springer Рейтинг: Цена: 10448.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Understanding the general laws of an effective system for transport of substances in cells is an important goal of systems and synthetic biology, this book helps us to answer why transport subsystem of a cell is arranged as it is. It describes linear and nonlinear programming, game theory for models of ion transport in different types of cells.
Автор: Vasilis Marmarelis Название: Analysis of Physiological Systems ISBN: 1461339723 ISBN-13(EAN): 9781461339724 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In studying physiological systems bioscientists are continually faced with the problem of providing descriptions of cause-effect relationships.
Описание: Reactive oxygen species (ROS) which include free radicals, peroxides, singlet oxygen, ozone, and nitrogen monoxide and dioxide free radicals, is an area of intense research. (2) the protection by ROS of an organism against invading organisms that cause infections;
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