Cecile Brocard; Andreas Hartig Molecular Machines Involved in Peroxisome Biogenesis and Maintenance 9783709117873

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Автор: Cecile Brocard; Andreas Hartig
Название: Molecular Machines Involved in Peroxisome Biogenesis and Maintenance
ISBN: 9783709117873
Издательство: Springer
Классификация:

Биология и науки о жизни

Клеточная биология (цитология)

ISBN-10: 3709117879
Обложка/Формат: Hardcover
Страницы: 543
Вес: 1.08 кг.
Дата издания: 12.08.2014
Язык: English
Издание: 2014 ed.
Иллюстрации: 34 illustrations, color; 17 illustrations, black and white; xv, 543 p. 51 illus., 34 illus. in color.
Размер: 234 x 156 x 30
Читательская аудитория: Professional & vocational
Основная тема: Cell Biology
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: In eukaryotes, lipid metabolism requires the function of peroxisomes. These multitasking organelles are also part of species-specific pathways such as the glyoxylate cycle in yeast and plants or the synthesis of ether lipid in mammals. Proteins required for the biogenesis of peroxisomes typically assemble in large molecular complexes, which participate in membrane formation, protein transport, peroxisome duplication and - inheritance during cell division. Peroxisomal function is essential for life. Mutations in PEX genes, encoding for biogenesis factors, are often associated with lethal disorders. The association of peroxisomes with other organelles suggests an extensive participation in organellar crosstalk. This book represents a state-of-the-art review in the field of peroxisome research encompassing the cell and molecular biology of peroxisome biogenesis and its diseases, the protein complexes involved in this process and the modern technologies applied to study them. The book is intended for graduate students, researchers and lecturers in biochemistry, molecular and cell biology with a biomedical background.
Дополнительное описание: Peroxisome biogenesis and function: History and Discovery of peroxins.- Human cell lines to study peroxisome biogenesis.- Mouse models to study peroxisome biogenesis.- Metabolic interaction between peroxisome and Mitochondria.- Peroxisomal Diseases:The Ze

Molecular Machines Involved in Peroxisome Biogenesis and Maintenance, Cecile Brocard; Andreas Hartig