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The Physical Basis of Bacterial Quorum Communication, Stephen J. Hagen


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Автор: Stephen J. Hagen
Название:  The Physical Basis of Bacterial Quorum Communication
ISBN: 9781493914012
Издательство: Springer
Классификация:

ISBN-10: 1493914014
Обложка/Формат: Hardcover
Страницы: 252
Вес: 0.54 кг.
Дата издания: 30.09.2014
Серия: Biological and Medical Physics, Biomedical Engineering
Язык: English
Размер: 234 x 156 x 16
Читательская аудитория: Science
Основная тема: Biological and Medical Physics, Biophysics
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Quorum sensing (QS) describes a chemical communication behavior that is nearly universal among bacteria. Individual cells release a diffusible small molecule (an autoinducer) into their environment. A high concentration of this autoinducer serves as a signal of high population density, triggering new patterns of gene expression throughout the population. However QS is often much more complex than this simple census-taking behavior. Many QS bacteria produce and detect multiple autoinducers, which generate quorum signal cross talk with each other and with other bacterial species. QS gene regulatory networks respond to a range of physiological and environmental inputs in addition to autoinducer signals. While a host of individual QS systems have been characterized in great molecular and chemical detail, quorum communication raises many fundamental quantitative problems which are increasingly attracting the attention of physical scientists and mathematicians. Key questions include: What kinds of information can a bacterium gather about its environment through QS? What physical principles ultimately constrain the efficacy of diffusion-based communication? How do QS regulatory networks maximize information throughput while minimizing undesirable noise and cross talk? How does QS function in complex, spatially structured environments such as biofilms? Previous books and reviews have focused on the microbiology and biochemistry of QS. With contributions by leading scientists and mathematicians working in the field of physical biology, this volume examines the interplay of diffusion and signaling, collective and coupled dynamics of gene regulation, and spatiotemporal QS phenomena. Chapters will describe experimental studies of QS in natural and engineered or microfabricated bacterial environments, as well as modeling of QS on length scales spanning from the molecular to macroscopic. The book aims to educate physical scientists and quantitative-oriented biologists on the application of physics-based experiment and analysis, together with appropriate modeling, in the understanding and interpretation of the pervasive phenomenon of microbial quorum communication.
Дополнительное описание: Chapter 1. Introduction.- Chapter 2. Modeling of Signal Transduction by The Quorum-Sensing Pathway in the Vibrios.- Chapter 3. Stochastic Effects in Quorum Sensing.- Chapter 4. Spatial Structure of Microbes in Nature and the Biophysics of Cell-Cell Commun



The Physical Basis of Bacterial Quorum Communication

Автор: Stephen J. Hagen
Название: The Physical Basis of Bacterial Quorum Communication
ISBN: 1493947362 ISBN-13(EAN): 9781493947362
Издательство: Springer
Рейтинг:
Цена: 15672.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Quorum sensing (QS) describes a chemical communication behavior that is nearly universal among bacteria. Chapters will describe experimental studies of QS in natural and engineered or microfabricated bacterial environments, as well as modeling of QS on length scales spanning from the molecular to macroscopic.

The Physical Microbe: An Introduction to Noise, Control, and Communication in the Prokaryotic Cell

Автор: Hagen Stephen J.
Название: The Physical Microbe: An Introduction to Noise, Control, and Communication in the Prokaryotic Cell
ISBN: 1643278916 ISBN-13(EAN): 9781643278919
Издательство: Mare Nostrum (Eurospan)
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Цена: 15048.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

The new field of physical biology fuses biology and physics. New technologies have allowed researchers to observe the inner workings of the living cell, one cell at a time. With an abundance of new data collected on individual cells, including observations of individual molecules and their interactions, researchers are developing a quantitative, physics-based understanding of life at the molecular level. They are building detailed models of how cells use molecular circuits to gather and process information, signal to each other, manage noise and variability, and adapt to their environment.

This book narrows down the scope of physical biology by focusing on the microbial cell. It explores the physical phenomena of noise, feedback, and variability that arise in the cellular information-processing circuits used by bacteria. It looks at the microbe from a physics perspective, to ask how the cell optimizes its function to live within the constraints of physics. It introduces a physical and information based -- as opposed to microbiological -- perspective on communication and signaling between microbes.

The book is aimed at non-expert scientists who wish to understand some of the most important emerging themes of physical biology, and to see how they help us to understand the most basic forms of life.

The Physical Microbe: An Introduction to Noise, Control, and Communication in the Prokaryotic Cell

Автор: Stephen J. Hagen
Название: The Physical Microbe: An Introduction to Noise, Control, and Communication in the Prokaryotic Cell
ISBN: 1681745283 ISBN-13(EAN): 9781681745282
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 5643.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Narrows down the scope of physical biology by focusing on the microbial cell. It explores the physical phenomena of noise, feedback, and variability that arise in the cellular information-processing circuits used by bacteria. It also looks at the microbe from a physics perspective, to ask how the cell optimizes its function to live within the constraints of physics.


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