Описание: Apoptosis is currently one of the fastest moving fields in biology with spectacular progress made over the past few years in delineating the molecular It is now indisputable that apoptosis mechanisms which underlie this process.
Описание: This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions.The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.
Автор: L. Nover; W. Berg; G. Butschak; M. Luckner; B. Par Название: Cell Differentiation ISBN: 3642680224 ISBN-13(EAN): 9783642680229 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cell differentiation comprises five main aspects: (1) signal reception and transformation, (2) selective rearrangements of the genetic material, (3) differen- tial gene expression, (4) organization of gene expression programs and (5) intercellular coordination of cell differentiation within the developmental programs of multicellular organisms.
Автор: Lugli Название: T-Cell Differentiation ISBN: 1493965468 ISBN-13(EAN): 9781493965465 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides protocols to successfully apply cutting-edge technologies to characterize the biology of T cells at an unprecedented level of complexity. Chapters guide readers through flow cytometry and fluorescence-activated cell sorting, the behaviour of single T cells after adoptive cell transfer (ACT), single cell gene expression by multiplex PCR, lentiviral transduction approaches, protocols to derive large numbers of early-differentiated memory T cells by using dedicated cytokines cocktails, approaches to measure telomerase activity in terminally differentiated T cells, and approaches to define Treg cells at the phenotypic and functional level. The final part of the book is dedicated to the analysis of the differentiation and effector functions of innate T cells, namely the well-known ?/? T cells, and the recently identified CD8+ mucosal associated invariant T (MAIT) cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, T-Cell Differentiation: Methods and Protocols aims to provide protocols that are fundamental to monitor the T cell compartment at the level of single cells in pathological and immunotherapy conditions.
Описание: Present trends in biological research show that it is necessary to know the structures thoroughly, from the ultrastructural cytological scale to the scale of tissue and organ arrangement, even for physiological research on either cells, tissues, or whole organs.
Описание: This series was established to create comprehensive treatises on specific topics in developmental biology. The specialist in any aspect of developmental biology should understand the experimental back- ground of the specialty and be able to place that body of information in context, in order to ascertain where additional research would be fruitful.
Автор: Rudnick Dorothea Название: Cellular Mechanics in Differentiation and Growth ISBN: 0691626812 ISBN-13(EAN): 9780691626819 Издательство: Wiley Рейтинг: Цена: 7128.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Here are the recent investigations of several distinguished biologists originally presented at the Fourteenth Symposium of the Society for the Study of Development and Growth. New tools and methods are used as they examine a wide range of cellular activities at various levels of plant and animal life. Originally published in 1956. The Princeton L
Автор: Jean-Pierre Saint-Jeannet Название: Neural Crest Induction and Differentiation ISBN: 1461497612 ISBN-13(EAN): 9781461497615 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Neural Crest Induction and Differentiation, written by an international panel of recognized leaders in the field, discusses all aspects of modern neural crest biology from its evolutionary significance, to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function. Each chapter provides an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance.
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