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Molecular Origins of Brain and Body Geometry, Antonio Lima-de-Faria


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Автор: Antonio Lima-de-Faria
Название:  Molecular Origins of Brain and Body Geometry
ISBN: 9783319060552
Издательство: Springer
Классификация:



ISBN-10: 3319060554
Обложка/Формат: Hardcover
Страницы: 188
Вес: 0.72 кг.
Дата издания: 04.11.2014
Язык: English
Издание: 2014 ed.
Иллюстрации: 105 illustrations, color; 15 illustrations, black and white; xv, 188 p. 120 illus., 105 illus. in color.
Размер: 217 x 285 x 15
Читательская аудитория: Professional & vocational
Основная тема: Animal Genetics and Genomics
Подзаголовок: Plato's Concept of Reality is Reversed
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: New concepts arise in science when apparently unrelated fields of knowledge are put together in a coherent way. The recent results in molecular biology allow to explain the emergence of body patterns in animals that before could not be understood by zoologists. There are no ”fancy curiosities” in nature. Every pattern is a product of a molecular cascade originating in genes and a living organism arises from the collaboration of these genes with the outer physical environment. Tropical fishes are as startling in their colors and geometric circles as peacocks. Tortoises are covered with the most regular triangles, squares and concentric circles that can be green, brown or yellow. Parallel scarlet bands are placed side by side of black ones along the body of snakes. Zebras and giraffes have patterns which are lessons in geometry, with their transversal and longitudinal stripes, their circles and other geometric figures. Monkeys, like the mandrills, have a spectacularly colored face scarlet nose with blue parallel flanges and yellow beard. All this geometry turns out to be highly molecular. The genes are many and have been DNA sequenced. Besides they not only deal with the coloration of the body but with the development of the brain and the embryonic process. A precise scenario of molecular events unravels in the vertebrates. It may seem far-fetched, but the search for the origin of this geometry made it mandatory to study the evolution of matter and the origin of the brain. It turned out that matter from its onset is pervaded by geometry and that the brain is also a prisoner of this ordered construction. Moreover, the brain is capable of altering the body geometry and the geometry of the environment changes the brain. Nothing spectacular occurred when the brain arrived in evolution. Not only it came after the eye, which had already established itself long ago, but it had a modest origin. It started from sensory cells on the skin that later aggregated into clusters of neurons that formed ganglia. It also became evident that pigment cells, that decide the establishment of the body pattern, originate from the same cell population as neurons (the neural crest cells). This is a most revealing result because it throws light on the power that the brain has to rapidly redirect the coloration of the body and to change its pattern. Recent experiments demonstrate how the brain changes the body geometry at will and within seconds, an event that could be hardly conceived earlier. Moreover, this change is not accidental it is related to the surrounding environment and is also used as a mating strategy. Chameleons know how to do it as well as flat fishes and octopuses. No one would have dared to think that the brain had its own geometry. How could the external geometry of solids or other figures of our environment be apprehended by neurons if these had no architecture of their own? Astonishing was that the so called ”simple cells”, in the neurons of the primary visual cortex, responded to a bar of light with an axis of orientation that corresponded to the axis of the cell’s receptive field. We tend to consider our brain a reliable organ. But how reliable is it? From the beginning the brain is obliged to transform reality. Brain imagery involves: form, color, motion and sleep. Unintentionally these results led to unexpected philosophical implications. Plato’s pivotal concept that ”forms” exist independently of the material world is reversed. Atoms have been considered to be imaginary for 2,000 years but at present they can be photographed, one by one, with electron microscopes. The reason why geometry has led the way in this inquiry is due to the fact that where there is geometry there is utter simplicity coupled to rigorous order that underlies the phenomenon where it is recognized. Order allows variation but imposes at the same time a canalization that is patent in what we call evolution.
Дополнительное описание: Introduction.- Part I: The Skeleton - the Primary Structure that Sets Vertebrates Apart - is an Evasive Structure.- Well-Defined Geometric Patterns Appeared in Animal Evolution Independently of the Skeleton.- Astonishing Gene Permanence throughout Vertebr



Biochemistry and  Molecular Biology,  5 edition

Автор: Snape Alison
Название: Biochemistry and Molecular Biology, 5 edition
ISBN: 0199609497 ISBN-13(EAN): 9780199609499
Издательство: Oxford Academ
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Цена: 6651.00 р.
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Описание: The ideal text for any bioscience student encountering biochemistry and molecular cell biology for the first time. Exceptionally clear explanations, frequent diagrams, and a user-friendly design and layout ensure that the text provides a perfect introduction to this complex yet fascinating subject area.

Methods in Molecular Biophysics: Structure, Dynamics, Function for Biology and Medicine, 2 ed.

Автор: Zaccai, Nathan R. (University of Cambridge) Serdyuk, Igor N. Zaccai, Joseph
Название: Methods in Molecular Biophysics: Structure, Dynamics, Function for Biology and Medicine, 2 ed.
ISBN: 1107056373 ISBN-13(EAN): 9781107056374
Издательство: Cambridge Academ
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Цена: 9029.00 р.
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Описание: Reflecting the significant developments of the past decade, this textbook explains key physical methods in modern biology. Each method is illustrated through real-world examples, alongside background information designed for both physicists and biologists, making this an ideal resource for students in biophysics at science and medical schools.

Molecular Biology and Genomics,

Автор: Cornel Mulhardt
Название: Molecular Biology and Genomics,
ISBN: 0120885468 ISBN-13(EAN): 9780120885466
Издательство: Elsevier Science
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Цена: 6772.00 р.
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Описание: Never before has it been so critical for lab workers to possess the proper tools and methodologies necessary to determine the structure, function, and expression of the corresponding proteins encoded in the genome. Mulhardt's Molecular Biology and Genomics helps aid in this daunting task by providing the reader with tips and tricks for more successful lab experiments. This strategic lab guide explores the current methodological variety of molecular biology and genomics in a simple manner, addressing the assets and drawbacks as well as critical points. It also provides short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods.

Essential Molecular Biology V1

Автор: Brown
Название: Essential Molecular Biology V1
ISBN: 0199636427 ISBN-13(EAN): 9780199636426
Издательство: Oxford Academ
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Цена: 9425.00 р. 13464.00 -30%
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Описание: This text is a guide to the basic techniques needed for molecular biology. It concentrates on the preparation, purification and handling of nucleic acids.

Molecular Biology, 2nd Edition

Автор: David P. Clark
Название: Molecular Biology, 2nd Edition
ISBN: 0123785944 ISBN-13(EAN): 9780123785947
Издательство: Elsevier Science
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Цена: 8104.00 р.
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Описание: The last quarter of the 20th century saw major scientific revolutions in genetics and computer technology. This title reflects massive surge in our understanding of the molecular foundations of genetics. It introduces basic concepts followed by more specific applications as the text evolves.

Molecular Biology and Biotechnology

Автор: Kreuzer
Название: Molecular Biology and Biotechnology
ISBN: 1555814719 ISBN-13(EAN): 9781555814717
Издательство: Taylor&Francis
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Цена: 8422.00 р.
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Описание: The third edition of this widely praised, best-selling textbook (formerly Recombinant DNA and Biotechnology) provides clear, indispensable information in cell and molecular biology that explains the exciting advances in biology and biotechnology. Because the field changes so rapidly, the need to provide crucial background information has never been more urgent. This text provides the vital information, latest knowledge, and clear-headed approaches that provide a basis for rationally discussing the interrelationship of science, technology, and society.

Additionally, the authors significantly added to their explanations of the societal issues that this new research raises. They provide critical thinking tools and processes to analyze issues such as gene flow in plants, animal cloning, genetic screening, and embryonic stem cells. In addition to providing the latest information on scientific foundations and technological applications of biotechnology, the book provides numerous activities to bring this exciting science to life.

Specifically, the text addresses biotechnology applications and attendant societal issues including therapeutic cloning, embryonic stem cells, genetic testing, food safety, and potential environmental impacts. The teacher volume includes all of the information contained within the student v lume, and it also incorporates numerous pedagogical resources. For instance, the instructor's volume includes a comprehensive CD-ROM containing chapter figures, templates and worksheets, laboratory resources, and teaching resources.

Additionally, the authors explain the nuts and bolts of runing a molecular biology laboratory, such as aseptic technique, using micropipettes, keeping microbial cultures well fed and happy, and crucial safety steps. This title updates and revises the best-selling text formerly titled Recombinant DNA and Biotechnology. It is written in a clear, easy-to-understand language that makes complicated information accessible to those with minimal background in this area.

It serves as both a textbook and a laboratory activities manual. It is designed for those instructors interested in 'problem-based' approaches for teaching and learning. It includes activities for both wet and dry laboratory settings.

It teaches essential critical thinking skills. It provides a companion instructor CD-ROM with many valuable teaching implements including worksheets, templates, and teaching tips. It presents activities that have been field tested, most for more than a decade.

Molecular Biology of RNA

Автор: Elliott Michael
Название: Molecular Biology of RNA
ISBN: 0199288372 ISBN-13(EAN): 9780199288373
Издательство: Oxford Academ
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Цена: 6493.00 р.
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Описание: Molecular Biology of RNA provides a broad survey of RNA structure and function. Describing the life cycle of an RNA, it reveals how hugely diverse gene products stem from a relatively modest gene pool. It also describes how RNA molecules have a range of biological functions beyond messenger RNA, including catalysts and regulatory molecules.

Algorithms in Structural Molecular Biology

Автор: Donald Bruce R.
Название: Algorithms in Structural Molecular Biology
ISBN: 0262015595 ISBN-13(EAN): 9780262015592
Издательство: MIT Press
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Цена: 11850.00 р.
Наличие на складе: Нет в наличии.

Описание:

An overview of algorithms important to computational structural biology that addresses such topics as NMR and design and analysis of proteins.

Using the tools of information technology to understand the molecular machinery of the cell offers both challenges and opportunities to computational scientists. Over the past decade, novel algorithms have been developed both for analyzing biological data and for synthetic biology problems such as protein engineering. This book explains the algorithmic foundations and computational approaches underlying areas of structural biology including NMR (nuclear magnetic resonance); X-ray crystallography; and the design and analysis of proteins, peptides, and small molecules.

Each chapter offers a concise overview of important concepts, focusing on a key topic in the field. Four chapters offer a short course in algorithmic and computational issues related to NMR structural biology, giving the reader a useful toolkit with which to approach the fascinating yet thorny computational problems in this area. A recurrent theme is understanding the interplay between biophysical experiments and computational algorithms. The text emphasizes the mathematical foundations of structural biology while maintaining a balance between algorithms and a nuanced understanding of experimental data. Three emerging areas, particularly fertile ground for research students, are highlighted: NMR methodology, design of proteins and other molecules, and the modeling of protein flexibility.

The next generation of computational structural biologists will need training in geometric algorithms, provably good approximation algorithms, scientific computation, and an array of techniques for handling noise and uncertainty in combinatorial geometry and computational biophysics. This book is an essential guide for young scientists on their way to research success in this exciting field.

Cell and molecular biology

Автор: Karp, Gerald
Название: Cell and molecular biology
ISBN: 0470505761 ISBN-13(EAN): 9780470505762
Издательство: Wiley
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Цена: 7259.00 р.
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Описание: Karp continues to help biologists make important connections between key concepts and experimentation. The sixth edition explores core concepts in considerable depth and presents experimental detail when it helps to explain and reinforce the concepts. The majority of discussions have been modified to reflect the latest changes in the field.

Molecular Biology  Principles of Genome Function

Автор: Craig Nancy
Название: Molecular Biology Principles of Genome Function
ISBN: 0199658579 ISBN-13(EAN): 9780199658572
Издательство: Oxford Academ
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Цена: 9186.00 р.
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Описание: A fresh, distinctive approach to the teaching of molecular biology. With its focus on key principles, its emphasis on the commonalities that exist between the three kingdoms of life, and its integrated coverage of experimental methods and approaches, Molecular Biology is the perfect companion to any molecular biology course.

Virus-Host Interactions: Methods and Protocols (Methods in Molecular Biology)

Автор: Susanne M. Bailer (Editor), Diana Lieber (Editor)
Название: Virus-Host Interactions: Methods and Protocols (Methods in Molecular Biology)
ISBN: 1627036008 ISBN-13(EAN): 9781627036009
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This volume covers various aspects of virological research, including molecular interactions and regulatory mechanisms on the protein as well as the RNA level. It features step-by-step, readily reproducible protocols and key implementation advice.

Immunoproteomics: Methods and Protocols (Methods in Molecular Biology)

Автор: Kelly M. Fulton (Editor), Susan M. Twine (Editor)
Название: Immunoproteomics: Methods and Protocols (Methods in Molecular Biology)
ISBN: 1627035885 ISBN-13(EAN): 9781627035880
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Providing diverse, up-to-date approaches and techniques for studying the immunoproteome, this Methods in Molecular Biology book offers materials lists, step-by-step reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


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