Maria Diakonova, PhD Recent Advances in Prolactin Research 9783319121130

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Автор: Maria Diakonova, PhD
Название: Recent Advances in Prolactin Research
ISBN: 9783319121130
Издательство: Springer
Классификация:

Медицинское оборудования и методики его эксплуатации

Медицинские исследования

Физиология

Эндокринология

ISBN-10: 3319121138
Обложка/Формат: Hardcover
Страницы: 281
Вес: 0.60 кг.
Дата издания: 15.12.2014
Серия: Advances in Experimental Medicine and Biology
Язык: English
Издание: 2015 ed.
Иллюстрации: 6 tables, black and white; 45 illustrations, color; 9 illustrations, black and white; viii, 281 p. 54 illus., 45 illus. in color.
Размер: 234 x 156 x 18
Читательская аудитория: Professional & vocational
Основная тема: Human Physiology
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Recent Advances in Prolactin Research summarizes the current knowledge of prolactin (PRL), PRL receptor, PRL-dependent signaling pathways, the role of PRL in oncogenesis and PRL crosstalk with other oncogenic factors. The chapters are written by experts in these fields and focus on identifying and reviewing timely experimental findings that provide new insights into the expanding role of PRL in the pathophysiology associated with a variety of human conditions. Prolactin is a peptide hormone that is best known for its role in lactation. Prolactin also has an influence on hematopoiesis and angiogenesis, and is involved in the regulation of blood clotting through several pathways. Although PRL was discovered more than 80 years ago, the understanding of PRL signaling and its relationship to various pathologies is still very incomplete. PRL is not only a pituitary hormone with an important role in reproduction, but PRL also acts as a cytokine, modulating a wide variety of physiological processes. For example, data gathered during the last decade have demonstrated that locally produced PRL acts as the autocrine/paracrine factor and plays a contributory role during breast oncogenesis. In fact, the scientific and clinical communities have suggested that the manipulation of the PRL axis may lead to the successful treatment of breast cancer. However, recent work has demonstrated that the role of the PRL axis is much more complex than first envisaged.
Дополнительное описание: Prolactin in adipose tissue: regulation and functions.- Signaling pathways regulating pituitary lactotrope homeostasis and tumorigenesis.- The many faces of prolactin in breast cancer.- Regulation of blood vessels by prolactin and vasoinhibins.- Tyrosyl p

Recent Advances in Prolactin Research, Maria Diakonova, PhD