Photoinduced Phenomena in Nucleic Acids II, Mario Barbatti; Antonio Carlos Borin; Susanne Ullr
Автор: Astrid Sigel; Helmut Sigel; Roland K. O. Sigel Название: Interplay between Metal Ions and Nucleic Acids ISBN: 9401782946 ISBN-13(EAN): 9789401782944 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions;
Автор: Yo Kikuchi; Elena Y. Rykova Название: Extracellular Nucleic Acids ISBN: 3642264190 ISBN-13(EAN): 9783642264191 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Following their emergence as key players in biology and the medical sciences, this book covers newly developing fields related to extracellular nucleic acids, including their basic biology, their ecology and their implications for medical science.
Автор: Jurga Название: Modified Nucleic Acids in Biology and Medicine ISBN: 3319341731 ISBN-13(EAN): 9783319341736 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is comprised of 18 chapters, covering various aspects of DNA modification and RNA modified bases. It also discusses in detail circular RNA, therapeutic oligonucleotides and their different properties. The chemical nature of DNA, RNA, protein and lipids makes these macromolecules easily modifiable, but they are also susceptible to damage from both endogenous and exogenous agents. Alkylation and oxidation show a potential to disrupt the cellular redox equilibrium and cause cellular damage leading to inflammation and even chronic disease. Furthermore, DNA damage can drive mutagenesis and the resulting DNA sequence changes can induce carcinogenesis and cancer progression. Modified nucleosides can occur as a result of oxidative DNA damage and RNA turnover, and are used as markers for various diseases. To function properly some RNA needs to be chemically modified post-transcriptionally. Dysregulation of the RNA-modification pattern or of the levels of the enzymes that catalyze these modifications alters RNA functionality and can result in complex phenotypes, likely due to defects in protein translation. While modifications are best characterized in noncoding ribonucleic acids like tRNA and rRNA, coding mRNAs have also been found to contain modified nucleosides. This book is a valuable resource, not only for graduate students but also researchers in the fields of molecular medicine and molecular biology.
Автор: R.F. Khairutdinov; Jochen Mattay; H.D. Roth; P. Su Название: Photoinduced Electron Transfer IV ISBN: 3662149877 ISBN-13(EAN): 9783662149874 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1. K. Zamaraev, R. Khairutdinov: Photoinduced Electron Tunneling Reactions in Chemistry and Biology 2. P. Suppan: The Marcus Inverted Region 3. H.D. Roth: Structure and Reactivity of Organic Radical Cations
Автор: Jochen Mattay; M.A. Fox; D. Gust; S.V. Lymar; J. M Название: Photoinduced Electron Transfer III ISBN: 3662150174 ISBN-13(EAN): 9783662150177 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The work presented in this thesis involves a number of sophisticated experiments highlighting novel applications of the Pixel Imaging Mass Spectrometry (PImMS) camera in the field of photoinduced molecular dynamics.
Описание: This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications.
Автор: Volker A. Erdmann; Jan Barciszewski Название: From Nucleic Acids Sequences to Molecular Medicine ISBN: 364243083X ISBN-13(EAN): 9783642430831 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Written by leading experts in the field , this book covers hot topics such as small interference RNAs for gene silencing in molecular biology and medicine. Includes numerous illustrations.
Автор: Neidle, Stephen Название: Therapeutic Applications of Quadruplex Nucleic Acids ISBN: 0128103728 ISBN-13(EAN): 9780128103722 Издательство: Elsevier Science Рейтинг: Цена: 15327.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The study of G-quadruplexes has emerged in recent years as an important focus of research in nucleic acids. This is now a rapidly growing area, not least because of its potential as a novel approach to cancer therapeutics, and there is much current activity on the design of quadruplex-selective small-molecule ligandsand the study of their cellular effects. This timely publication gives a uniquely integrated view of quadruplex nucleic acids that will be a major resource in future drug-discovery strategies.Therapeutic Applications of Quadruplex Nucleic Acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics.Written by a world leader in this field, this book is a vital resource for researchers in medicinal chemistry, chemical biology, structural biology, drug discovery, and pharmacology in cancer and other therapeutic areas, as well as for chemists and biologists working on nucleic acids, and will be useful for both active researchers and students in these areas.
Название: Modified nucleic acids ISBN: 3319271091 ISBN-13(EAN): 9783319271095 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Emissive 5-Substituted Uridine Analogues.- Fluorescent purine nucleosides and their applications.- Thiazole orange-tethered nucleic acids and ECHO probes for fluorometric detection of nucleic acids.- Synthetic wavelength-shifting fluorescent probes of nucleic acids.- DNA Assisted Multichromophore Assembly.- Polymerase Synthesis of Base-Modified DNA.- Photo-cross-linking Reaction in Nucleic Acids - Chemistry and Applications.- Site-Directed Spin Labeling for EPR Studies of Nucleic Acids.- Non-Covalent Modification of Double Stranded DNA at the Mismatch and Bulged Site.- 2',4'-Bridged Nucleic Acids for Targeting Double-Stranded DNA.- Specific Recognition of Single Nucleotide by Alkylating Oligonucleotides and Sensing of 8-oxoguanine.- Genetic alphabet expansion by unnatural base pair creation and its application to high affinity DNA aptamers.
Автор: D. Boulter Название: Nucleic Acids and Proteins in Plants I ISBN: 3642682391 ISBN-13(EAN): 9783642682391 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
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