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Lyophilized Biologics and Vaccines, Dushyant Varshney; Manmohan Singh


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Цена: 22359.00р.
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Автор: Dushyant Varshney; Manmohan Singh
Название:  Lyophilized Biologics and Vaccines
ISBN: 9781493923823
Издательство: Springer
Классификация:




ISBN-10: 149392382X
Обложка/Формат: Hardcover
Страницы: 401
Вес: 0.78 кг.
Дата издания: 21.05.2015
Язык: English
Издание: 2015 ed.
Иллюстрации: 39 tables, black and white; 68 illustrations, color; 31 illustrations, black and white; xi, 401 p. 99 illus., 68 illus. in color.
Размер: 234 x 156 x 24
Читательская аудитория: Professional & vocational
Основная тема: Vaccine
Подзаголовок: Modality-Based Approaches
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание:

Preface.- Part I - Lyophilization History and Fundamentals.- History of Lyophilization.- Heterogeneity of protein environments in frozen solutions and in the dried state.- Advance understanding of buffer behavior during lyophilization.- Advances in Instrumental Analysis Applied to the Development of Lyophilization Cycles.- New Developments in Controlled Nucleation: Commercializing VERISEQ(R) Nucleation technology.- Part II - Lyophilized Biologics and Vaccines - Modality Considerations.- Lyophilized Biologics.- Lyophilization of Therapeutic Proteins in Vials - Process Scale-up and Advances in Quality by Design.- Advances in Process Analytical Technology in Freeze Drying.- Process Scale-up and Optimization of Lyophilized Vaccine Products.- Stabilization of Plasmid DNA and Lipid-based Therapeutics as Dehydrated Formulations.- Part III - Advances in Alternate Drying.- Alternatives to Vial Lyophilization.- Spray Drying of Biopharmaceuticals.- Current Trends and Advances in Bulk Crystallization and Freeze Drying of Biopharmaceuticals.- Case Studies and Examples of Biopharmaceutical Modalities.- Processed by Bulk Crystallization or Bulk Freeze Drying.- Part IV- Regulatory, Packaging and Technology Transfer Considerations.- Lyophilization of Biologics - An FDA Perspective.- Recent Trends in Lyophilized Delivery Devices and Packaging.- Lyophilization Technology Transfer towards Product Launch.




Principles of General, Organic and Biological Chemistry

Автор: Smith
Название: Principles of General, Organic and Biological Chemistry
ISBN: 1259252272 ISBN-13(EAN): 9781259252273
Издательство: McGraw-Hill
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Цена: 10123.00 р.
Наличие на складе: Поставка под заказ.

Описание: Contributors of Volume 2: Tossi Aaron, Arnold E. Burkart, Isabel Carley, Gerald P. Dyck, Nancy Ferguson, Jane Frazee, Ruth Pollock Hamm, Maureen Kennedy, Susan Kennedy, Marcia Lunz, Joachim Matthesius, Grace Nash, Erik Nielsen, Sue Ellen Page, Martha Pline Polon, Jacobeth Postl, Pat Riello, Konnie Saliba, Miriam Samuelson, Donald Slagel, Judith Thomas, Martha Maybury WamplerBesetzung:voice, recorder and percussion

Safety of Biologics Therapy

Автор: Baldo
Название: Safety of Biologics Therapy
ISBN: 3319304704 ISBN-13(EAN): 9783319304700
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This long overdue title provides a comprehensive, up-to-date, state-of-the art review of approved biologic therapies, with coverage of mechanisms of action, Indications for therapy, immunogenicity and a detailed examination of adverse effects and safety of the many and diverse therapeutic agents presented in a total of 13 chapters. It is predicted that by 2016, biologics will make up half of the world's 20 top-selling drugs and by 2018, biologic medicine sales will account for almost half of the world's 100 biggest selling drugs. Recombinant proteins dominate the growing list of the more than 200 approved biotherapeutic agents with targeted antibodies, fusion proteins and receptors; cytokines; hormones; enzymes; proteins involved in blood-clotting, homeostasis and thrombosis; vaccines; botulinum neurotoxins; and, more recently, biosimilar preparations, comprising the majority of approved biologics. Written with clinicians, other health care professionals, and researchers in mind, Safety of Biologics Therapy examines, in a single volume, the full range of issues surrounding the safety of approved biologic therapies. A good understanding of the risks and safety issues of modern biologics therapy is increasingly being demanded of all those connected with their development, handling, prescribing, administration and subsequent patient management. In addition to being of great value to clinicians in all branches of medicine, and to nurses, pharmacists and researchers, this book will prove invaluable for students taking undergraduate and graduate courses in the above disciplines and in the biomedical sciences.

Mammalian Cell Cultures for Biologics Manufacturing

Автор: Weichang Zhou; Anne Kantardjieff
Название: Mammalian Cell Cultures for Biologics Manufacturing
ISBN: 364254049X ISBN-13(EAN): 9783642540493
Издательство: Springer
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Цена: 39130.00 р.
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Описание: Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification.

Vaccines and Autoimmunity

Автор: Yehuda Shoenfeld,Nancy Agmon–Levin
Название: Vaccines and Autoimmunity
ISBN: 1118663438 ISBN-13(EAN): 9781118663431
Издательство: Wiley
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Цена: 22485.00 р.
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Описание: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants specifically aluminum in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.

Pharmaco-Imaging in Drug and Biologics Development

Автор: Brian R. Moyer; Narayan P.S. Cheruvu; Tom C.-C. Hu
Название: Pharmaco-Imaging in Drug and Biologics Development
ISBN: 1461482461 ISBN-13(EAN): 9781461482468
Издательство: Springer
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Цена: 23757.00 р.
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Описание: The volume aim to be a comprehensive overview of the drug and biologic development process that is often called "the valley of death" (pre-IND through approval) where high costs of studies and high rates of product failure are part of the drug development landscape.


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